Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

Glutathione Transferases as Targets for Cancer Therapy

(2012) Paolo Ruzza et al.   Anti-Cancer Agents in Medicinal Chemistry

A Diet Rich in Olive Oil Phenolics Reduces Oxidative Stress in the Heart of SAMP8 Mice by Induction of Nrf2-Dependent Gene Expression

(2012) Banu Bayram et al.   REJUVENATION RESEARCH

Which Sources of Flavonoids: Complex Diets or Dietary Supplements?

(2012) Sarah Egert et al.   Advances in Nutrition

Drug combinations with quercetin: doxorubicin plus quercetin in human breast cancer cells

(2011) Davide Staedler et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

2'-Hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma

(2011) L. D. Nagaprashantha et al.   CARCINOGENESIS

Role of Residue 87 in the Activity and Regioselectivity of Clozapine Metabolism by Drug-Metabolizing CYP102A1 M11H: Application for Structural Characterization of Clozapine GSH Conjugates

(2011) V. Rea et al.   DRUG METABOLISM AND DISPOSITION

Possibilities to increase the effectiveness of doxorubicin in cancer cells killing

(2011) Veronika Hanušová et al.   DRUG METABOLISM REVIEWS

Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents

(2011) Larry G. Higgins et al.   DRUG METABOLISM REVIEWS

Glutathione transferases: a structural perspective

(2011) Aaron Oakley   DRUG METABOLISM REVIEWS

Antioxidant and prooxidant properties of flavonoids

(2011) D. Procházková et al.   FITOTERAPIA

The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer

(2011) Kenneth D. Tew et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effect of diethylcarbamazine, butylated hydroxy anisole and methyl substituted chalcone on filarial parasite Setaria cervi: Proteomic and biochemical approaches

(2011) Sushma Rathaur et al.   Journal of Proteomics

Hypolipidaemic and hypoglycaemic effects of total flavonoids from seed residues of Hippophae rhamnoides L. in mice fed a high-fat diet

(2011) Jiesi Wang et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

(2011) Na Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines

(2011) Andrea Sau et al.   Molecular BioSystems

The role of nanomedicine in the imaging and therapy of thrombosis

(2011) Jason R McCarthy et al.   Nanomedicine

Glutathione S-transferase M1 and T1 polymorphism and response to neoadjuvant chemotherapy (CAF) in breast cancer patients

(2011) Anjali Mishra et al.   SURGERY TODAY

Glutathione transferases and development of new principles to overcome drug resistance

(2010) Andrea Sau et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mechanisms of 4-Hydroxy-2-nonenal Induced Pro- and Anti-Apoptotic Signaling

(2010) Pankaj Chaudhary et al.   BIOCHEMISTRY

Identification of chalcones as in vivo liver monofunctional phase II enzymes inducers

(2010) Mauricio Cabrera et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New cancer treatment strategy using combination of green tea catechins and anticancer drugs

(2010) Masami Suganuma et al.   CANCER SCIENCE

Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death

(2010) E Laborde   CELL DEATH AND DIFFERENTIATION

Identification of Quinone Imine Containing Glutathione Conjugates of Diclofenac in Rat Bile

(2010) Daniel J. Waldon et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Characterization of Glutathione Conjugates of Duloxetine by Mass Spectrometry and Evaluation ofin SilicoApproaches to Rationalize the Site of Conjugation for Thiophene Containing Drugs

(2010) Guosheng Wu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Protective effect of catechin and quercetin on chlorpyrifos-induced lung toxicity in male rats

(2010) Fatma Gokce Uzun et al.   FOOD AND CHEMICAL TOXICOLOGY

GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer

(2010) A.L. Oliveira et al.   GENETICS AND MOLECULAR RESEARCH

Protoapigenone, a natural derivative of apigenin, induces mitogen-activated protein kinase-dependent apoptosis in human breast cancer cells associated with induction of oxidative stress and inhibition of glutathione S-transferase π

(2010) Wen-Ying Chen et al.   INVESTIGATIONAL NEW DRUGS

Butein Up-Regulates the Expression of the π Class of GlutathioneS-Transferase in Rat Primary Hepatocytes through the ERK/AP-1 Pathway

(2010) Hebron C. Chang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Common structural features of mapeg-a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism

(2010) Per-Johan Jakobsson et al.   PROTEIN SCIENCE

Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding

(2009) Min-Ho Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Glutathione Transferases Are Structural and Functional Outliers in the Thioredoxin Fold

(2009) Holly J. Atkinson et al.   BIOCHEMISTRY

Cadmium-induced hepatotoxicity in rats and the protective effect of naringenin

(2009) J. Renugadevi et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Regulation of Phase II Enzymes by Genistein and Daidzein in Male and Female Swiss Webster Mice

(2009) Erik B. Froyen et al.   JOURNAL OF MEDICINAL FOOD

Increased Sensitivity of Glutathione S-Transferase P-Null Mice to Cyclophosphamide-Induced Urinary Bladder Toxicity

(2009) D. J. Conklin et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Glutathione S-transferase pi regulates UV-induced JNK signaling in SH-SY5Y neuroblastoma cells

(2009) Margarida Castro-Caldas et al.   NEUROSCIENCE LETTERS

Effects of Quercetin and Catechin on Hepatic Glutathione-S Transferase (GST), NAD(P)H Quinone Oxidoreductase 1 (NQO1), and Antioxidant Enzyme Activity Levels in Rats

(2009) Heike Wiegand et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

In vitro antifilarial activity of glutathione S-transferase inhibitors

(2009) Lakshmy Srinivasan et al.   PARASITOLOGY RESEARCH

Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy

(2008) Kohji Noguchi et al.   ADVANCED DRUG DELIVERY REVIEWS

Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?

(2008) Barry Halliwell   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The influence of diet composition on phase I and II biotransformation enzyme induction

(2008) Jaime L. Rudolf et al.   ARCHIVES OF TOXICOLOGY

Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa

(2008) Corine Ekhart et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Mammalian Cytosolic Glutathione Transferases

(2008) Daniel Dourado et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Protective effect of the cruciferous vegetable mustard leaf (Brassica campestris) against in vivo chromosomal damage and oxidative stress induced by γ-radiation and genotoxic chemicals

(2008) Ashu B. Tiku et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Health effects of quercetin: From antioxidant to nutraceutical

(2008) Agnes W. Boots et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of Filarial Glutathione-S-transferase by various classes of compounds and their evaluation as novel antifilarial agents

(2008) R. Ahmad et al.   HELMINTHOLOGIA

GlutathioneS-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury

(2008) M. Isabel Lucena et al.   HEPATOLOGY

Novel Role for GlutathioneS-Transferase π

(2008) Danyelle M. Townsend et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Green tea catechins in chemoprevention of cancer: A molecular docking investigation into their interaction with glutathione S-transferase (GST P1-1)

(2008) Roberto Artali et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Interactions of Polyphenols with the P450 System: Possible Implications on Human Therapeutics

(2008) M. Gomez-Lechon et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Do glutathione-S-transferase polymorphisms influence response to intravenous cyclophosphamide therapy in idiopathic nephrotic syndrome?

(2008) Sheetal V. Sharda et al.   PEDIATRIC NEPHROLOGY

Glutathione transferases from parasites: A biochemical view

(2007) Anayetzin Torres-Rivera et al.   ACTA TROPICA