System-Dependent Outcomes during the Evaluation of Drug Candidates as Inhibitors of Cytochrome P450 (CYP) and Uridine Diphosphate Glucuronosyltransferase (UGT) Enzymes: Human Hepatocytes versus Liver Microsomes versus Recombinant Enzymes

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Title
System-Dependent Outcomes during the Evaluation of Drug Candidates as Inhibitors of Cytochrome P450 (CYP) and Uridine Diphosphate Glucuronosyltransferase (UGT) Enzymes: Human Hepatocytes versus Liver Microsomes versus Recombinant Enzymes
Authors
Keywords
-
Journal
Drug Metabolism and Pharmacokinetics
Volume 25, Issue 1, Pages 16-27
Publisher
Japanese Society for the Study of Xenobiotics
Online
2010-03-08
DOI
10.2133/dmpk.25.16

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