Metabolite Formation Kinetics and Intrinsic Clearance of Phenacetin, Tolbutamide, Alprazolam, and Midazolam in Adenoviral Cytochrome P450-Transfected HepG2 Cells and Comparison with Hepatocytes and In Vivo

Title
Metabolite Formation Kinetics and Intrinsic Clearance of Phenacetin, Tolbutamide, Alprazolam, and Midazolam in Adenoviral Cytochrome P450-Transfected HepG2 Cells and Comparison with Hepatocytes and In Vivo
Authors
Keywords
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Journal
DRUG METABOLISM AND DISPOSITION
Volume 38, Issue 9, Pages 1449-1455
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Online
2010-05-26
DOI
10.1124/dmd.110.033605

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