If the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?

Title
If the KI Is Defined by the Free Energy of Binding to P-Glycoprotein, Which Kinetic Parameters Define the IC50 for the Madin-Darby Canine Kidney II Cell Line Overexpressing Human Multidrug Resistance 1 Confluent Cell Monolayer?
Authors
Keywords
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Journal
DRUG METABOLISM AND DISPOSITION
Volume 38, Issue 2, Pages 260-269
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Online
2009-11-05
DOI
10.1124/dmd.109.029843

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