An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N- -N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing

Title
An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N- -N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing
Authors
Keywords
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Journal
DRUG METABOLISM AND DISPOSITION
Volume 37, Issue 3, Pages 502-513
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Online
2008-12-17
DOI
10.1124/dmd.108.021931

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