An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine

Title
An Intestinal Epithelium-Specific Cytochrome P450 (P450) Reductase-Knockout Mouse Model: Direct Evidence for a Role of Intestinal P450s in First-Pass Clearance of Oral Nifedipine
Authors
Keywords
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Journal
DRUG METABOLISM AND DISPOSITION
Volume 37, Issue 3, Pages 651-657
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Online
2008-12-05
DOI
10.1124/dmd.108.025429

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