Editorial Material
Hematology
Mary Eapen
Summary: This article reports on the outcomes of allogeneic hematopoietic stem cell transplantation (allo-HSCT) and conservative management for adult patients with inborn errors of immunity (IEI).
Article
Criminology & Penology
Allison D. D. Redlich, Mary Catlin, Talley Bettens
Summary: This study demonstrates that participants' willingness to conform to assigned conditions affects their legal decisions, with non-conforming participants being less likely to confess, plead guilty, and waive Miranda rights. The researchers emphasize the importance of considering non-conforming participants in analyses and interpretations.
JOURNAL OF EXPERIMENTAL CRIMINOLOGY
(2023)
Article
Agricultural Economics & Policy
Harold Alderman, Daniel O. Gilligan, Jessica Leight, Michael Mulford, Heleene Tambet
Summary: Poultry is seen as a promising value chain for women due to its accessibility, low start-up costs, and nutritional benefits for children. An experimental intervention in rural Ethiopia found that the transfer of poultry packages increased egg consumption and sales among children and adult women.
Review
Biochemistry & Molecular Biology
Teresa Gonzalez Munoz, Ana Teresa Amaral, Pilar Puerto-Camacho, Hector Peinado, Enrique de Alava
Summary: Endoglin has been identified as a potential disease biomarker and therapeutic target, playing various roles in physiological and pathological processes. It acts as a co-receptor in the TGF beta pathway and can also be released in soluble form to affect cell signaling. In cancer, endoglin may contribute to both oncogenic and non-oncogenic phenotypes, opening up possibilities for targeted therapies within the tumor microenvironment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Statistics & Probability
Chan Park, Hyunseung Kang
Summary: This article presents two assumption-lean methods for analyzing ITT effects and network effects in CRTs, and reanalyzes a study on the effect of face masks and hand sanitizers on the transmission of 2008 interpandemic influenza in Hong Kong.
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
(2023)
Article
Surgery
Zhi Ven Fong, Fidel Lopez Verdugo, Carlos Fernandez-del Castillo, Cristina R. Ferrone, Jill N. Allen, Lawrence S. Blaszkowsky, Jeffrey W. Clark, Aparna R. Parikh, David P. Ryan, Colin D. Weekes, Theodore S. Hong, Jennifer Y. Wo, Keith D. Lillemoe, Motaz Qadan
Summary: FOLFIRINOX is increasingly used in the management of pancreatic ductal adenocarcinoma (PDAC), but neoadjuvant therapy may have complications that prevent surgical exploration. This study found that most patients were able to complete planned neoadjuvant chemotherapy and undergo surgery, but some could not due to poor tolerability or disease progression.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2023)
Article
Clinical Neurology
Julien Delrieu, Bruno Vellas, Sophie Guyonnet, Christelle Cantet, Vitaliy Ovod, Yan Li, James Bollinger, Randall Bateman, Sandrine Andrieu, MAPT DSA Grp
Summary: The study demonstrated a positive cognitive effect of MI plus omega 3 in subjects with positive blood amyloid, but further confirmation is needed. Conversely, no cognitive effect was observed in both positive and negative blood amyloid groups at the 60-month visit.
ALZHEIMERS RESEARCH & THERAPY
(2023)
Article
Mathematical & Computational Biology
Ao Yuan, Lida Wang, Ming T. Tan
Summary: The article introduces a new type of regression model - set-regression, specifically designed to address subgroup analysis problems and improve accuracy in identifying subgroups. This method is easy to use and has shown superior performance in simulation studies.
STATISTICS IN MEDICINE
(2022)
Article
Oncology
Barbara Burtness, Danny Rischin, Richard Greil, Denis Soulieres, Makoto Tahara, Gilberto de Castro Jr, Amanda Psyrri, Irene Brana, Neus Baste, Prakash Neupane, Ase Bratland, Thorsten Fuereder, Brett G. M. Hughes, Ricard Mesia, Nuttapong Ngamphaiboon, Tamara Rordorf, Wan Zamaniah Wan Ishak, Joy Ge, Ramona F. Swaby, Burak Gumuscu, Kevin Harrington
Summary: This study analyzed the PD-L1 expression subgroups in the KEYNOTE-048 trial and found that higher PD-L1 expression levels were associated with increased efficacy of pembrolizumab or pembrolizumab-chemotherapy. However, the subgroup analysis of PD-L1 CPS < 1 was limited by a small number of participants, indicating the need for additional predictive biomarkers for low PD-L1-expressing HNSCC.
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Hanna Gerlovin, Daniel C. Posner, Yuk-Lam Ho, Christopher T. Rentsch, Janet P. Tate, Joseph T. Jr Jr King, Katherine E. Kurgansky, Ioana Danciu, Lauren Costa, Franciel A. Linares, Ian D. Goethert, Daniel A. Jacobson, Matthew S. Freiberg, Edmon Begoli, Sumitra Muralidhar, Rachel B. Ramoni, Georgia Tourassi, J. Michael Gaziano, Amy C. Justice, David R. Gagnon, Kelly Cho
Summary: An analysis conducted on hospitalized US veterans with COVID-19 found no apparent benefit associated with the use of hydroxychloroquine alone or in combination with azithromycin. In fact, there was an increased risk of intubation when hydroxychloroquine was used in combination with azithromycin.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
Review
Medicine, General & Internal
Antonio Franco, Flavia Proietti, Veronica Palombi, Gabriele Savarese, Michele Guidotti, Costantino Leonardo, Fabio Ferro, Claudio Manna, Giorgio Franco
Summary: The treatment of varicocele in infertility is still a controversial issue. Recent scientific evidence shows that varicocele treatment can improve semen parameters and pregnancy rates. The aim of treatment in adults is to improve current fertility status, while in adolescents, it is to prevent testicular injury and maintain future fertility. Correct indication seems to be the key to successful varicocele treatment. This study reviews and summarizes the current evidence on varicocele treatment, focusing on surgical indications in adolescents and adults, as well as other specific situations.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biology
Lu Mao
Summary: In this paper, a general framework is established to study the asymptotic properties of the intent-to-treat Wilcoxon-Mann-Whitney test in randomized experiments with nonignorable noncompliance. The Pitman efficiencies of the intent-to-treat Wilcoxon-Mann-Whitney and t tests are derived under location-shift alternatives. It is shown that the former is superior if the compliers are more likely to be found in high-density regions or if the noncompliers tend to reside in the tails. The results can help researchers choose the more efficient test for existing data and calculate sample size for future trials with noncompliance.
Article
Rheumatology
Maike H. M. Wientjes, Evy Ulijn, Wietske Kievit, Robert B. M. Landewe, Inger Meek, Nathan den Broeder, Noortje van Herwaarden, Bart J. F. van den Bemt, Lise M. Verhoef, Alfons A. den Broeder
Summary: This study compared the additional value and costs of using a biomarker-guided strategy for RA patients compared to usual care. The results showed that patients in the biomarker strategy spent an extra 2.9 months in low disease activity or remission over 48 months, with similar total costs. Cost-effectiveness was dependent on a combination of early proactive tapering and high medication costs.
Article
Computer Science, Information Systems
Lu Zhang, Jialie Shen, Jian Zhang, Jingsong Xu, Zhibin Li, Yazhou Yao, Litao Yu
Summary: People's increasing reliance on the internet for information sharing and acquisition has made the multimodal marketing advertorial, generated by 'We Media' accounts, vital on social media platforms. Understanding the marketing intent is crucial for effective advertising, but the disguised nature of advertorials poses challenges in accurately recognizing and analyzing its intent. In this study, we propose a novel Multimodal-based Marketing Intent Analysis scheme (MMIA) that tackles this problem and provides insights into the extent and topics of marketing intent in social news.
IEEE TRANSACTIONS ON MULTIMEDIA
(2022)
Article
Engineering, Electrical & Electronic
Luis Velasco, Marco Signorelli, Oscar Gonzalez de Dios, Chrysa Papagianni, Roberto Bifulco, Juan Jose Vegas Olmos, Simon Pryor, Gino Carrozzo, Julius Schulz-Zander, Mehdi Bennis, Ricardo Martinez, Filippo Cugini, Claudio Salvadori, Vincent Lefebvre, Luca Valcarenghi, Marc Ruiz
Summary: The article proposes an end-to-end and ubiquitous secure machine learning (ML)-powered intent-based networking (IBN) framework for autonomously taking proactive actions for service assurance.
IEEE COMMUNICATIONS MAGAZINE
(2021)
