Pharmacogenetic Biomarkers as Tools for Pharmacoepidemiology of Severe Adverse Drug Reactions

Can knowledge of germline markers of toxicity optimize dosing and efficacy of cancer therapy?

(2012) Daniel Crona et al.   Biomarkers in Medicine

Effects of CYP4F2 Polymorphism on Response to Warfarin During Induction Phase: A Prospective, Open-Label, Observational Cohort Study

(2012) Idit Bejarano-Achache et al.   CLINICAL THERAPEUTICS

Genetic determinants of response to cardiovascular drugs

(2012) Quinn S. Wells et al.   CURRENT OPINION IN CARDIOLOGY

Statin-Induced Myotoxicity: Pharmacokinetic Differences among Statins and the Risk of Rhabdomyolysis, with Particular Reference to Pitavastatin

(2012) Alberico L. Catapano   Current Vascular Pharmacology

Evidence-Based Strategies for the Optimization of Pharmacotherapy in Older People

(2012) Eva Topinková et al.   DRUGS & AGING

The primary role of hepatic metabolism in idiosyncratic drug-induced liver injury

(2012) David E Amacher   Expert Opinion on Drug Metabolism & Toxicology

Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays

(2012) Sabine Lohmann et al.   METHODS

Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation

(2012) Frank S Ong et al.   PHARMACOGENOMICS

Pharmacogenetics and pharmacogenomics: role of mutational analysis in anti-cancer targeted therapy

(2012) A Savonarola et al.   PHARMACOGENOMICS JOURNAL

Adverse Drug Reactions in Children—A Systematic Review

(2012) Rebecca Mary Diane Smyth et al.   PLoS One

Human Genome Sequencing in Health and Disease

(2011) Claudia Gonzaga-Jauregui et al.   Annual Review of Medicine

Drug Hypersensitivity and Human Leukocyte Antigens of the Major Histocompatibility Complex

(2011) Mandvi Bharadwaj et al.   Annual Review of Pharmacology and Toxicology

Old Versus New Oral Anticoagulants: Focus on Pharmacology

(2011) Jawed Fareed et al.   Annual Review of Pharmacology and Toxicology

Using Genome-Wide Association Studies to Identify Genes Important in Serious Adverse Drug Reactions

(2011) Ann K. Daly   Annual Review of Pharmacology and Toxicology

Current progress in pharmacogenetics

(2011) John D. Blakey et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacogenomic testing: Relevance in medical practice: Why drugs work in some patients but not in others

(2011) J. P. KITZMILLER et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Assessment of nonsteroidal anti-inflammatory drug-induced hepatotoxicity

(2011) José AG Agúndez et al.   Expert Opinion on Drug Metabolism & Toxicology

Epidemiology and characteristics of adverse drug reactions caused by drug–drug interactions

(2011) Lara Magro et al.   Expert Opinion On Drug Safety

Pharmacogenomics and adverse drug reactions: the case of statins

(2011) Mariano A Giorgi et al.   EXPERT OPINION ON PHARMACOTHERAPY

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

HLA alleles and drug hypersensitivity reactions

(2011) T. Profaizer et al.   International Journal of Immunogenetics

Pharmacogenetics of cutaneous adverse drug reactions

(2011) Michiko AIHARA   JOURNAL OF DERMATOLOGY

Managing the challenge of chemically reactive metabolites in drug development

(2011) B. Kevin Park et al.   NATURE REVIEWS DRUG DISCOVERY

Part 2: Pharmacogenetic Variability in Drug Transport and Phase I Anticancer Drug Metabolism

(2011) M. J. Deenen et al.   ONCOLOGIST

Safety aspects of antiepileptic drugs-focus on pharmacovigilance

(2011) Cecilie Johannessen Landmark et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake

(2011) M. Niemi et al.   PHARMACOLOGICAL REVIEWS

Cardiovascular pharmacogenetics

(2011) Renier Myburgh et al.   PHARMACOLOGY & THERAPEUTICS

Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis

(2011) M. Alberton et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Pharmacogenetics and human genetic polymorphisms

(2010) Ann K. Daly   BIOCHEMICAL JOURNAL

The c.-1639G>A polymorphism of the VKORC1 gene in Serbian population: retrospective study of the variability in response to oral anticoagulant therapy

(2010) Mirjana K Kovac et al.   BLOOD COAGULATION & FIBRINOLYSIS

Prediction of Severe Adverse Drug Reactions Using Pharmacogenetic Biomarkers

(2010) Masahiro Tohkin et al.   Drug Metabolism and Pharmacokinetics

Cancer Pharmacogenomics and Pharmacoepidemiology: Setting a Research Agenda to Accelerate Translation

(2010) Andrew N. Freedman et al.   JNCI-Journal of the National Cancer Institute

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Genome-wide association studies in pharmacogenomics

(2010) Ann K. Daly   NATURE REVIEWS GENETICS

Consumption of serum lipid-reducing drugs in Serbia compared with Scandinavian countries: a population-based study, 2004-2008

(2010) Ana Sabo et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Pharmacogenetics of drug hypersensitivity

(2010) Elizabeth J Phillips et al.   PHARMACOGENOMICS

Practical recommendations for pharmacogenomics-based prescription: 2010 ESF–UB Conference on Pharmacogenetics and Pharmacogenomics

(2010) Laurent Becquemont et al.   PHARMACOGENOMICS

Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

(2010) D Wang et al.   PHARMACOGENOMICS JOURNAL

Improving reporting of adverse drug reactions: Systematic review

(2010) Mariam Molokhia   Clinical Epidemiology

Pharmacogenetics and the Pharmaceutical Industry

(2009) Jan. Raaijmakers et al.   CURRENT PHARMACEUTICAL DESIGN

Human drug hepatotoxicity: a contemporary clinical perspective

(2009) David N Assis et al.   Expert Opinion on Drug Metabolism & Toxicology

Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect

(2009) Peirang Cao et al.   FASEB JOURNAL

Reporting genetic association studies: the STREGA statement

(2009) Erik von Elm et al.   LANCET

Cardiovascular pharmacogenomics and individualized drug therapy

(2009) Naveen L. Pereira et al.   Nature Reviews Cardiology

Genome-wide association studies: powerful tools for improving drug safety and efficacy

(2009) David Gurwitz et al.   PHARMACOGENOMICS

Pharmacogenomics of adverse drug reactions: practical applications and perspectives

(2009) Laurent Becquemont   PHARMACOGENOMICS

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

(2009) Fumihiko Takeuchi et al.   PLoS Genetics

Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis

(2008) M. E. Sarasquete et al.   BLOOD

Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy

(2008) Helene M. Devold et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Prospective Study of Warfarin Dosage Requirements Based on CYP2C9 and VKORC1 Genotypes

(2008) M-S Wen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Warfarin therapy: in need of improvement after all these years

(2008) Stephen E Kimmel   EXPERT OPINION ON PHARMACOTHERAPY

Pharmacogenomics and Drug Toxicity

(2008) Yusuke Nakamura   NEW ENGLAND JOURNAL OF MEDICINE

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathway-based association analysis of genome-wide screening data suggest that genes associated with the ??-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia

(2008) Toshiya Inada et al.   Pharmacogenetics and Genomics

Practical guidelines for diagnosis and early management of drug-induced liver injury

(2008) Kazuto Tajiri et al.   WORLD JOURNAL OF GASTROENTEROLOGY