Journal
DRUG AND ALCOHOL DEPENDENCE
Volume 99, Issue 1-3, Pages 132-140Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.drugalcdep.2008.07.013
Keywords
Costs and cost analysis; Opioid-related disorders; Methadone; Buprenorphine
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Funding
- Doris Duke Charitable Foundation (Jones)
- Robert Wood Johnson Foundation Substance Abuse Policy Research Program
- National Institutes on Drug Abuse [R01 DA 09803-04A2, K24 DA00445]
- Center for Substance Abuse Treatment [99M002071, 98M002016]
- Yale University School of Medicine Office of Student Research
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA009803, R01DA019511, K24DA000445] Funding Source: NIH RePORTER
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The cost of providing and receiving treatment for opioid dependence can determine its adoption. To compare the cost of clinic-based methadone (MC, n = 23), office-based methadone (MO, it = 2 1), and office-based buprenorphine (130, it = 34) we performed an analysis of treatment and patient costs over 6 months of maintenance in patients who had previously been stabilized for at least I year. We performed statistical comparisons using ANOVA and chi-square tests and performed a sensitivity analysis varying cost estimates and intensity of clinical contact. The cost of providing I month of treatment per patient was $147 (MC), $220 (MO) and $336 (130) (p < 0.001). Mean monthly medication cost was $93 (MC), $86 (MO) and $257 (130) (1), < 0.001). The cost to patients was $92 (MC), $63 (MO) and $38 (130) (P = 0.102). Sensitivity analyses, varying cost estimates and clinical contact, result in total monthly costs of $117 to $183 (MC), $149 to $279 (MO), $292 to $499 (BO). Monthly patient costs were $84 to $133 (MC), $55 to $105 (MO) and $34 to $65 (130). We conclude that providing clinic-based methadone is least expensive. The price of buprenorphine accounts for a major portion of the difference in costs. For patients, office-based treatment may be less expensive. (c) 2008 Elsevier Ireland Ltd. All rights reserved.
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