Article
Biotechnology & Applied Microbiology
Ali Yousefinia, Maryam Khodadadi, Sobhan Mortazavi-Derazkola
Summary: In this study, ZnO/CuO@BVE nanocomposites were synthesized using an environmentally-friendly method and characterized using various analytical techniques. The nanocomposites showed excellent photocatalytic and antibacterial properties under optimized conditions.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2023)
Article
Green & Sustainable Science & Technology
Kavitha Thangavelu, Ranjith Rajendran, Senthilkumar Palanisamy, Priyadharsan Arumugam, Rojviroon Thammasak
Summary: This study investigates the use of in-situ synthesized FeWO4/g-C3N4 heterostructures as photocatalysts for the decomposition of tetracycline. The nanocomposites proved to have outstanding photocatalytic degradation and adsorption performance, achieving a high removal rate within a short period of time. Additionally, the heterostructures displayed excellent stability and recyclability, indicating their potential for developing new sunlight-driven catalysts.
MATERIALS TODAY SUSTAINABILITY
(2023)
Review
Biochemistry & Molecular Biology
Tianxi Li, Lulu Li, Fangyuan Du, Lei Sun, Jichao Shi, Miao Long, Zeliang Chen
Summary: This review focuses on antifungal peptides isolated from various microorganisms, outlining their antifungal activity, toxic effects, and mechanisms of action, as well as common solutions to mitigate their toxicity. This work serves as a useful reference for further clinical research and the development of safe antifungal drugs with high efficiencies and broad application spectra.
Article
Chemistry, Physical
Bharati Debi Biswas, Moushumi Dutta Purkayastha, Ekta Tiwari, Shanku Denrah, Mitali Sarkar, Gopala Krishna Darbha, Tapas Pal Majumder
Summary: Manganese doped zinc oxide (MZ) nanocomposites with excellent photocatalytic activity were synthesized using co-precipitation method, and effectively degraded toxic organic dye under light irradiation. Among different molar ratios of Mn/Zn, MZ3 (1:25) nanocomposites exhibited the best photocatalytic activity, attributed to its high surface area and reaction rate.
SURFACES AND INTERFACES
(2021)
Article
Microbiology
Ashley L. Cunningham, Orhi Esarte Palomero, Bradley J. Voss, M. Stephen Trent, Bryan W. Davies
Summary: Otilonium bromide, a poorly absorbed oral medication used for irritable bowel syndrome, has been found to have broad-spectrum antibacterial and antifungal activity, including against multidrug-resistant strains. This suggests that otilonium bromide could be a new option for intestinal antimicrobial therapy targeting enteric pathogens.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Chemistry, Physical
Gaojian Lv, Lifang Sun, Hui Gao, Chengcheng Ma, Wen Li, Shougang Chen
Summary: The construction of heterojunction is an effective strategy to achieve charge separation and improve photocatalytic activity. In this study, stable reduced Cu2O/Ag/Bi2MoO6 nano-composites with high-efficiency antibacterial activities were synthesized. The results showed that Cu2O/Ag/BMO could promote electron-hole separation and extend the lifetime of photogenerated carriers, resulting in improved antimicrobial ability. The prepared Cu2O/Ag/BMO composites have great application prospects in the antifouling field.
APPLIED SURFACE SCIENCE
(2023)
Article
Pharmacology & Pharmacy
Shabnam Yavari, Kayode Olaifa, Darya Shafiee, Reza Rasuli, Mehdi Shafiee
Summary: Microorganisms are emerging contaminants in the environment and pose significant risks to public health. Conventional disinfection methods are often ineffective and have drawbacks. This study presents a method to synthesize nanomaterials with antimicrobial properties and demonstrates their effectiveness against Escherichia coli and Candida albicans. The synthesized nanomaterials show potential for biomedical applications.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Biochemistry & Molecular Biology
Mauricio Osorio, Marcela Carvajal, Alejandra Vergara, Estefania Butassi, Susana Zacchino, Carolina Mascayano, Margarita Montoya, Sophia Mejias, Marcelo Cortez-San Martin, Yesseny Vasquez-Martinez
Summary: Prenylated flavonoids are important natural compounds with significant biological activity, particularly in antimicrobial functions. Compounds 11, 12, and 13 showed strong inhibitory activity against human pathogenic fungi and clinical isolated Staphylococcus aureus MRSA, indicating the key structural requirements for antibacterial activity. Additionally, the combination of prenylated flavonoids with commercial antibiotics significantly enhanced the antibacterial activity against drug-resistant bacteria.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Chemistry, Medicinal
Yan-Yan Ding, Han Zhou, Bao-Qi Peng-Deng, Bao-Qi Zhang, Zhi-Jun Zhang, Guang-Han Wang, Shao-Yong Zhang, Zheng-Rong Wu, Yi-Rong Wang, Ying-Qian Liu
Summary: Since the isolation of the first natural carbazole alkaloid, murrayanine, from Mwraya Spreng, carbazole alkaloid derivatives have attracted wide attention for their anti-tumor, anti-viral, and anti-bacterial activities. Recent research has shown that carbazole alkaloids and their derivatives exhibit diverse biological activities. This study provides the first comprehensive description of the antifungal and antibacterial activities of carbazole alkaloids in the past decade (2012-2022), including both natural and partially synthesized compounds. The challenges and problems faced by this class of alkaloids are also summarized. This paper will facilitate further exploration of carbazole alkaloids.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Review
Microbiology
Abdelmoneim K. Abdalla, Mutamed M. Ayyash, Amin N. Olaimat, Tareq M. Osaili, Anas A. Al-Nabulsi, Nagendra P. Shah, Richard Holley
Summary: Exopolysaccharides (EPSs) are metabolites synthesized and excreted by various microorganisms, playing important biological functions in interactions between bacteria and their environments, protection against hostile conditions, and evasion of immune responses. Numerous studies have shown the broad antimicrobial activities of EPS against pathogenic microbes. This review focuses on the in vitro and in vivo antimicrobial activities of different EPSs against foodborne bacterial, fungal, and viral pathogens, as well as the mechanisms of action and methods of measurement.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Chemistry, Inorganic & Nuclear
Reda Hassan Huseen Amasha, Samyah Darwish Saddig Jastaniah, Zahraa Haleem Al-qaim, Fadhil Hussam, Abdullah Shakir, Milad Kazemnejadi
Summary: Ag@Fosfd. and Ag@Fosfo. NPs were in situ prepared and functionalized using TAIm[Fosfo.] and TAIm[Fosfd.] ILs reducing agents, respectively. They exhibited smaller diameter sizes (22 nm and 18 nm) compared to those synthesized using sodium citrate (30 nm). The in situ modification resulted in large negative zeta potentials, preventing agglomeration and allowing for ease of dispersion. These nanoparticles showed prominent antibacterial, anti-colon-cancer, and antifungal properties, with greater effectiveness than samples prepared by other methods. The presence of Fosmidomycin and Fosfomycin antibiotics on their surface contributed to their stability and reduced toxicity.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Review
Chemistry, Multidisciplinary
Varish Ahmad, Mohammad Omaish Ansari
Summary: Graphene and its nanocomposites have attracted significant interest due to their efficient antimicrobial properties. Graphene has found applications in tissue engineering and has been successfully conjugated with existing drugs to improve therapeutic efficacy. This review discusses the antimicrobial potential, synthesis, and toxicity of graphene-based nanomaterials in biological systems.
Article
Biochemistry & Molecular Biology
Sidra Batool Malik, Javed Iqbal Saggu, Asma Gul, Banzeer Ahsan Abbasi, Javed Iqbal, Saboora Waris, Yousef A. Bin Jardan, Wadie Chalgham
Summary: This study synthesized silver-graphene nanocomposites with antibacterial and photocatalytic properties, which have potential applications in removing microbial pathogens and industrial toxic wastes from water.
Review
Infectious Diseases
Heidi Silen, Enass Y. A. Salih, Eunice Ego Mgbeahuruike, Pia Fyhrqvist
Summary: Bacterial and fungal resistance to antibiotics is a global concern. African Combretum and Pteleopsis species have the potential to be used as sources for antimicrobial extracts and adjuvants. Combination treatments using these plant species can enhance each other's effects, making them potent antimicrobial agents. This review compiles information on the botany, ethnopharmacology, and appearance of African species of Combretum and Pteleopsis in herbal markets. Additionally, it summarizes the phytochemistry, antimicrobial potency, and combination effects of these extracts and compounds with conventional antibiotics.
Article
Environmental Sciences
Niloufar Torkian, Abbas Bahrami, Afrouzossadat Hosseini-Abari, Mohammad Mohsen Momeni, Meisam Abdolkarimi-Mahabadi, Ahmad Bayat, Pejman Hajipour, Hamed Amini Rourani, Mohammad Saeid Abbasi, Sima Torkian, Yangping Wen, Maryam Yazdan Mehr, Akbar Hojjati-Najafabadi
Summary: This paper investigates the synthesis, antibacterial, and photocatalytic properties of silver ion-exchanged natural zeolite/TiO2 photocatalyst nanocomposite, and proposes a facile method to synthesize this catalyst for the removal of antibiotics and bacteria from wastewaters.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Girgis Obaid, Menitte Eroy, Jie Zhao, Shazia Bano, Mari Mino-Kenudson, Tayyaba Hasan
Summary: The presence of desmoplasia in pancreatic ductal adenocarcinoma (PDAC) is associated with poor treatment outcomes and reduced drug delivery. By analyzing collagen subtypes in PDAC tumors following different treatment regimens, immunofluorescence profiling can predict long-term survival and tumor growth inhibition. This information can aid in personalized treatment and improve patient survival.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Fatemeh Malekpour, Rashin Bahrami, Mahshid Hodjat, Neda Hakimiha, Behnam Bolhari, Aidin Sooratgar, Soheil Niavarzi
Summary: This study investigated the effect of photobiomodulation (PBM) therapy using an 808 nm diode laser on cellular modulation mechanisms in regenerative endodontic procedures (REPs). The results showed that PBM treatment significantly increased cell viability and migration, and enhanced the release of TGF-131 from dentin.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Pranathi Tata, Ramakrishnan Ganesan, Jayati Ray Dutta
Summary: Thin film coatings with potent antibacterial properties are widely used in medical devices, frequently touched surfaces, and food packaging. However, achieving antibacterial performance under both light and dark conditions remains a challenge. In this study, we successfully prepared AgBr-coated ZnO nanorod thin film architecture using a unique surfactant-mediated solution-phase spin-coating approach. The resulting structures showed dual functionality as antimicrobial agents and photosensitizers, effectively enhancing the visible-light photodisinfection efficacy of ZnO nanorods. The concentration of the surfactant-based precursor solution could be modulated to control the AgBr content. Additionally, components like urea and lactic acid were found to enhance the photocatalytic efficiency of the structures.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2024)
