Inhibition of hedgehog signal pathway by cyclopamine attenuates inflammation and articular cartilage damage in rats with adjuvant-induced arthritis

Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis

(2014) Oksana Kehoe et al.   Journal of Translational Medicine

Protein and mRNA expression of Shh, Smo and Gli1 and inhibition by cyclopamine in hepatocytes of rats with chronic fluorosis

(2014) Lina Zhao et al.   TOXICOLOGY LETTERS

Sonic Hedgehog Signaling Drives Proliferation of Synoviocytes in Rheumatoid Arthritis: A Possible Novel Therapeutic Target

(2014) Mingxia Wang et al.   Journal of Immunology Research

Curcumin potentiates the anti-arthritic effect of prednisolone in Freund's complete adjuvant-induced arthritic rats

(2013) Madhusudana Kuncha et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis

(2012) Adelheid Korb-Pap et al.   ANNALS OF THE RHEUMATIC DISEASES

Progression of joint damage despite control of inflammation in rheumatoid arthritis: a role for cartilage damage driven synovial fibroblast activity: Figure 1

(2012) Floris PJG Lafeber et al.   ANNALS OF THE RHEUMATIC DISEASES

Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage

(2012) F. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

Physical disability in rheumatoid arthritis is associated with cartilage damage rather than bone destruction

(2011) D. Aletaha et al.   ANNALS OF THE RHEUMATIC DISEASES

Enhanced tumor suppression by an ING4/IL-24 bicistronic adenovirus-mediated gene cotransfer in human non-small cell lung cancer cells

(2011) Y Zhu et al.   CANCER GENE THERAPY

Mechanism and evolution of cytosolic Hedgehog signal transduction

(2010) C. W. Wilson et al.   DEVELOPMENT

Inhibition of acid-sensing ion channels in articular chondrocytes by amiloride attenuates articular cartilage destruction in rats with adjuvant arthritis

(2010) Feng-Lai Yuan et al.   INFLAMMATION RESEARCH

The anti-arthritic effect of ursolic acid on zymosan-induced acute inflammation and adjuvant-induced chronic arthritis models

(2010) Suk-Yun Kang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Blocking hedgehog signaling might have therapeutic potential in OA

(2010) Jenny Buckland   Nature Reviews Rheumatology

Inhibition of Endogenous Hedgehog Signaling Protects Against Acute Liver Injury After Ischemia Reperfusion

(2010) Akshay Pratap et al.   PHARMACEUTICAL RESEARCH

The Correlation between Increased Serum Concentrations of Interleukin-6 Family Cytokines and Disease Activity in Rheumatoid Arthritis Patients

(2010) Soo-Jin Chung et al.   YONSEI MEDICAL JOURNAL

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

Cartilage homeostasis in health and rheumatic diseases

(2009) Mary B Goldring et al.   ARTHRITIS RESEARCH & THERAPY

Effects of infliximab therapy on biological markers of synovium activity and cartilage breakdown in patients with rheumatoid arthritis

(2008) H Marotte et al.   ANNALS OF THE RHEUMATIC DISEASES

Hedgehog Signaling in Mature Osteoblasts Regulates Bone Formation and Resorption by Controlling PTHrP and RANKL Expression

(2008) Kinglun Kingston Mak et al.   DEVELOPMENTAL CELL

Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2

(2008) Kiyomi Takahashi et al.   Journal of Neuroinflammation

Effects of the selective EP4antagonist, CJ-023,423 on chronic inflammation and bone destruction in rat adjuvant-induced arthritis

(2008) Takako Okumura et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY