Upregulation of P-glycoprotein expression by ophthalmic drugs in different corneal in-vitro models

Topical ocular delivery of fluoroquinolones

(2013) Pravin Pawar et al.   Expert Opinion on Drug Delivery

Hypoxia is a key regulator of limbal epithelial stem cell growth and differentiation

(2013) Chris Bath et al.   Stem Cell Research

Expression analysis of MDR1, BCRP and MRP3 transporter proteins in different in vitro and ex vivo cornea models for drug absorption studies

(2012) Jessica Verstraelen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Prevalidation of a Human Cornea Construct as an Alternative to Animal Corneas for In Vitro Drug Absorption Studies

(2012) Matthias Hahne et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In vitrocell culture models to study the corneal drug absorption

(2011) Stephan Reichl et al.   Expert Opinion on Drug Metabolism & Toxicology

Medical treatment of glaucoma: present and future

(2011) Paolo Fogagnolo et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Development of a serum-free human cornea construct for in vitro drug absorption studies: The influence of varying cultivation parameters on barrier characteristics

(2011) Matthias Hahne et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effect of Emergence of Fluoroquinolone Resistance on Intrinsic Expression of P-Glycoprotein Phenotype in Corneal Epithelial Cells

(2011) Megha Barot et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Characterization of PXR mediated P-glycoprotein regulation in intestinal LS174T cells

(2010) Bhavani Prasad Kota et al.   PHARMACOLOGICAL RESEARCH

Characterization of Human Corneal Epithelial Cell Model As a Surrogate for Corneal Permeability Assessment: Metabolism and Transport

(2009) C. D. Xiang et al.   DRUG METABOLISM AND DISPOSITION

Comparison of fluoroquinolones: cytotoxicity on human corneal epithelial cells

(2009) T-H Tsai et al.   EYE

Effects of Cytochrome P450 Inducers on the Gene Expression of Ocular Xenobiotic Metabolizing Enzymes in Rats

(2009) Toshimasa Sugamo et al.   JOURNAL OF HEALTH SCIENCE

Effluxing ABC transporters in human corneal epithelium

(2009) Kati-Sisko Vellonen et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84)

(2008) I.S. Haslam et al.   BIOCHEMICAL PHARMACOLOGY

Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition

(2008) T. Zhang et al.   DRUG METABOLISM AND DISPOSITION

Intestinal efflux transporters and drug absorption

(2008) Teruo Murakami et al.   Expert Opinion on Drug Metabolism & Toxicology

Fluoroquinolone Efflux Mediated by ABC Transporters

(2008) Ana I. Alvarez et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Molecular Design for Enhancement of Ocular Penetration

(2007) Yoshihisa Shirasaki   JOURNAL OF PHARMACEUTICAL SCIENCES