Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist

Methods and software tools for design evaluation in population pharmacokinetics-pharmacodynamics studies

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Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection

(2012) Stephen J Hopkins et al.   Journal of Neuroinflammation

Intravenous Anakinra can Achieve Experimentally Effective Concentrations in the Central Nervous System within a Therapeutic Time Window: Results of a Dose-Ranging Study

(2010) James Galea et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Systematic Review and Stratified Meta-analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke

(2009) Victoria Banwell et al.   Journal of Stroke & Cerebrovascular Diseases

Application of optimal design methodologies in clinical pharmacology experiments

(2008) Kayode Ogungbenro et al.   PHARMACEUTICAL STATISTICS

Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage

(2007) Ivelina Gueorguieva et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY