- Home
- Publications
- Publication Search
- Publication Details
Title
Integrated PK-PD and agent-based modeling in oncology
Authors
Keywords
Chemotherapy, Computer simulation, Mathematical modeling, Multiscale, Tumor growth and invasion, Translational research
Journal
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
Volume 42, Issue 2, Pages 179-189
Publisher
Springer Nature
Online
2015-01-14
DOI
10.1007/s10928-015-9403-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Novel, Patient-Specific Mathematical Pathology Approach for Assessment of Surgical Volume: Application to Ductal Carcinomain situof The Breast
- (2015) Mary E. Edgerton et al. Analytical Cellular Pathology
- Mechanistic pharmacokinetic/pharmacodynamic modeling of in vivo tumor uptake, catabolism, and tumor response of trastuzumab maytansinoid conjugates
- (2014) Russ Wada et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts
- (2014) S. C. Tate et al. CLINICAL CANCER RESEARCH
- Development of a sampling-based global sensitivity analysis workflow for multiscale computational cancer models
- (2014) Zhihui Wang et al. IET Systems Biology
- Graphics processing units accelerated semiclassical initial value representation molecular dynamics
- (2014) Dario Tamascelli et al. JOURNAL OF CHEMICAL PHYSICS
- Transport properties of pancreatic cancer describe gemcitabine delivery and response
- (2014) Eugene J. Koay et al. JOURNAL OF CLINICAL INVESTIGATION
- The effect of interstitial pressure on therapeutic agent transport: Coupling with the tumor blood and lymphatic vascular systems
- (2014) Min Wu et al. JOURNAL OF THEORETICAL BIOLOGY
- Lattice-free descriptions of collective motion with crowding and adhesion
- (2014) Stuart T. Johnston et al. PHYSICAL REVIEW E
- Mechanistic Modeling Identifies Drug-Uptake History as Predictor of Tumor Drug Resistance and Nano-Carrier-Mediated Response
- (2013) Jennifer Pascal et al. ACS Nano
- Mathematical modeling in cancer drug discovery
- (2013) Zhihui Wang et al. DRUG DISCOVERY TODAY
- The big challenges of big data
- (2013) Vivien Marx NATURE
- Preclinical Pharmacokinetic/Pharmacodynamic Models to Predict Schedule-Dependent Interaction Between Erlotinib and Gemcitabine
- (2013) Mengyao Li et al. PHARMACEUTICAL RESEARCH
- Impact of Diffusion Barriers to Small Cytotoxic Molecules on the Efficacy of Immunotherapy in Breast Cancer
- (2013) Hiranmoy Das et al. PLoS One
- Interstitial Fluid Flow and Drug Delivery in Vascularized Tumors: A Computational Model
- (2013) Michael Welter et al. PLoS One
- An Integrated Computational/Experimental Model of Lymphoma Growth
- (2013) Hermann B. Frieboes et al. PLoS Computational Biology
- Towards Predicting the Response of a Solid Tumour to Chemotherapy and Radiotherapy Treatments: Clinical Insights from a Computational Model
- (2013) Gibin G. Powathil et al. PLoS Computational Biology
- Antitumor Activity of Targeted and Cytotoxic Agents in Murine Subcutaneous Tumor Models Correlates with Clinical Response
- (2012) H. Wong et al. CLINICAL CANCER RESEARCH
- A Hybrid Cellular Automaton Model of Solid Tumor Growth and Bioreductive Drug Transport
- (2012) Nabila Kazmi et al. IEEE-ACM Transactions on Computational Biology and Bioinformatics
- Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin
- (2012) Dhaval K. Shah et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Models of collective cell behaviour with crowding effects: comparing lattice-based and lattice-free approaches
- (2012) M. J. Plank et al. Journal of the Royal Society Interface
- Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: Biological insights from a hybrid multiscale cellular automaton model
- (2012) Gibin G. Powathil et al. JOURNAL OF THEORETICAL BIOLOGY
- Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): From microscopic measurements to macroscopic predictions of clinical progression
- (2012) Paul Macklin et al. JOURNAL OF THEORETICAL BIOLOGY
- The effect of interstitial pressure on tumor growth: Coupling with the blood and lymphatic vascular systems
- (2012) Min Wu et al. JOURNAL OF THEORETICAL BIOLOGY
- Computational Medicine: Translating Models to Clinical Care
- (2012) R. L. Winslow et al. Science Translational Medicine
- The Pharmacokinetic/Pharmacodynamic Pipeline: Translating Anticancer Drug Pharmacology to the Clinic
- (2011) Qingyu Zhou et al. AAPS Journal
- Multiscale Cancer Modeling
- (2011) Thomas S. Deisboeck et al. Annual Review of Biomedical Engineering
- Theoretical optimization of Irinotecan-based anticancer strategies in the case of drug-induced efflux
- (2011) Annabelle Ballesta et al. APPLIED MATHEMATICS LETTERS
- A multiscale mechanobiological modelling framework using agent-based models and finite element analysis: application to vascular tissue engineering
- (2011) Houman Zahedmanesh et al. Biomechanics and Modeling in Mechanobiology
- Computational Modeling of Tumor Response to Vascular-Targeting Therapies—Part I: Validation
- (2011) Jana L. Gevertz Computational and Mathematical Methods in Medicine
- Hybrid Model of Erythropoiesis and Leukemia Treatment with Cytosine Arabinoside
- (2011) Polina Kurbatova et al. SIAM JOURNAL ON APPLIED MATHEMATICS
- Modeling Cell Movement and Chemotaxis Using Pseudopod-Based Feedback
- (2011) M. P. Neilson et al. SIAM JOURNAL ON SCIENTIFIC COMPUTING
- Clinically driven design of multi-scale cancer models: the ContraCancrum project paradigm
- (2011) K. Marias et al. Interface Focus
- Identification of Critical Molecular Components in a Multiscale Cancer Model Based on the Integration of Monte Carlo, Resampling, and ANOVA
- (2011) Zhihui Wang et al. Frontiers in Physiology
- Incorporation of Gemcitabine and Cytarabine into DNA by DNA Polymerase β and Ligase III/XRCC1
- (2010) A. S. Prakasha Gowda et al. BIOCHEMISTRY
- A theoretical quantitative model for evolution of cancer chemotherapy resistance
- (2010) Ariosto S Silva et al. Biology Direct
- FEM-Based 3-D Tumor Growth Prediction for Kidney Tumor
- (2010) Xinjian Chen et al. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
- Three-dimensional multispecies nonlinear tumor growth—II: Tumor invasion and angiogenesis
- (2010) Hermann B. Frieboes et al. JOURNAL OF THEORETICAL BIOLOGY
- Using adaptive model predictive control to customize maintenance therapy chemotherapeutic dosing for childhood acute lymphoblastic leukemia
- (2010) Sarah L. Noble et al. JOURNAL OF THEORETICAL BIOLOGY
- Identifying therapeutic targets in a combined EGFR-TGF R signalling cascade using a multiscale agent-based cancer model
- (2010) Z. Wang et al. MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA
- The biological effectiveness of targeted radionuclide therapy based on a whole-body pharmacokinetic model
- (2010) Joseph J Grudzinski et al. PHYSICS IN MEDICINE AND BIOLOGY
- Cross-scale, cross-pathway evaluation using an agent-based non-small cell lung cancer model
- (2009) Zhihui Wang et al. BIOINFORMATICS
- The virtual cell--a candidate co-ordinator for 'middle-out' modelling of biological systems
- (2009) D. C. Walker et al. BRIEFINGS IN BIOINFORMATICS
- Migration rules: tumours are conglomerates of self-metastases
- (2009) H Enderling et al. BRITISH JOURNAL OF CANCER
- Prediction of Drug Response in Breast Cancer Using Integrative Experimental/Computational Modeling
- (2009) H. B. Frieboes et al. CANCER RESEARCH
- Paradoxical Dependencies of Tumor Dormancy and Progression on Basic Cell Kinetics
- (2009) H. Enderling et al. CANCER RESEARCH
- Adaptive Therapy
- (2009) R. A. Gatenby et al. CANCER RESEARCH
- An implementation of the Expectation-Maximisation (EM) algorithm for population pharmacokinetic–pharmacodynamic modelling in ACSLXTREME
- (2009) James W.T. Yates COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
- Testing additivity of anticancer agents in pre-clinical studies: A PK/PD modelling approach
- (2009) M. Rocchetti et al. EUROPEAN JOURNAL OF CANCER
- Modeling of tumor growth and anticancer effects of combination therapy
- (2009) Gilbert Koch et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Evolution of cell motility in an individual-based model of tumour growth
- (2009) P. Gerlee et al. JOURNAL OF THEORETICAL BIOLOGY
- A change of strategy in the war on cancer
- (2009) Robert A. Gatenby NATURE
- Nonlinear modelling of cancer: bridging the gap between cells and tumours
- (2009) J S Lowengrub et al. NONLINEARITY
- Implementation and evaluation of various demons deformable image registration algorithms on a GPU
- (2009) Xuejun Gu et al. PHYSICS IN MEDICINE AND BIOLOGY
- Predicting drug pharmacokinetics and effect in vascularized tumors using computer simulation
- (2008) John P. Sinek et al. JOURNAL OF MATHEMATICAL BIOLOGY
- Individual-based and continuum models of growing cell populations: a comparison
- (2008) Helen Byrne et al. JOURNAL OF MATHEMATICAL BIOLOGY
- Three-dimensional multispecies nonlinear tumor growth—I
- (2008) S.M. Wise et al. JOURNAL OF THEORETICAL BIOLOGY
- Simulating brain tumor heterogeneity with a multiscale agent-based model: Linking molecular signatures, phenotypes and expansion rate
- (2008) Le Zhang et al. MATHEMATICAL AND COMPUTER MODELLING
- Preclinical pharmacokinetic/pharmacodynamic models of gefitinib and the design of equivalent dosing regimens in EGFR wild-type and mutant tumor models
- (2008) S. Wang et al. MOLECULAR CANCER THERAPEUTICS
- Computational modeling of brain tumors: discrete, continuum or hybrid?
- (2008) Zhihui Wang et al.
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now