Effect of Individual Fc Methionine Oxidation on FcRn Binding: Met252 Oxidation Impairs FcRn Binding More Profoundly than Met428 Oxidation

Published 2015 View Full Article

Authors

Keywords

monoclonal antibody, serum half-life, oxidation, critical quality attributes, neonatal Fc receptor, protein binding, surface plasmon resonance, HPLC, stability, calorimetry

Journal

JOURNAL OF PHARMACEUTICAL SCIENCES

Volume 104, Issue 2, Pages 368-377

Publisher

Elsevier BV

Online

2014-08-29

DOI

10.1002/jps.24136

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Reprint

Contact the author

Add your recorded webinar

Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.

Upload Now

Become a Peeref-certified reviewer

The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.

Get Started