Solid-State mAbs and ADCs Subjected to Heat-Stress Stability Conditions can be Covalently Modified with Buffer and Excipient Molecules

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Title
Solid-State mAbs and ADCs Subjected to Heat-Stress Stability Conditions can be Covalently Modified with Buffer and Excipient Molecules
Authors
Keywords
mass spectrometry, capillary electrophoresis, freeze-drying/lyophilization, stability, excipients, covalent modification, esterification, charge variants
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 104, Issue 2, Pages 652-665
Publisher
Elsevier BV
Online
2014-12-03
DOI
10.1002/jps.24276

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