Review
Neurosciences
Sophia C. Levis, Stephen V. Mahler, Tallie Z. Baram
Summary: Opioid use disorder (OUD) is not typically a singular psychiatric condition, with comorbid symptoms likely tied to various risk factors. Early life adversity may disrupt reward circuit development, potentially contributing to OUD and other comorbid neuropsychiatric disorders.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Biology
Sandra Cole, Stephen Wirkus
Summary: Opioid use disorder is a serious health issue in the USA, leading to addiction, disability, or overdose death. A mathematical model is proposed to predict the development of heroin use disorder in the population, highlighting the importance of specialty treatment facilities.
BULLETIN OF MATHEMATICAL BIOLOGY
(2022)
Review
Pharmacology & Pharmacy
Kathrine Louise Jensen, Soren Brogger Jensen, Kenneth Lindegaard Madsen
Summary: Psychostimulant use disorder is a major global health issue with no effective pharmacological treatments available. This review provides an overview of pharmacological treatments targeting different aspects of psychostimulant addiction, including the dopamine system, the glutamate system, and the severe side effects of quitting long-term use. Promising results have been found with drugs modulating the dopamine system, cognitive enhancers, and drugs targeting the glutamate system, but further research is needed for sufficient evidence of efficacy and tolerability.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Neurosciences
Justin Hudak, Adam W. Hanley, William R. Marchand, Yoshio Nakamura, Brandon Yabko, Eric L. Garland
Summary: The study demonstrates that mindfulness meditation can improve neural function in veterans receiving LTOT and reduce opioid dosing. Mindfulness meditation has a positive effect on enhancing inhibitory control over opioid dose escalation behaviors.
NEUROPSYCHOPHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Xiaohang Che, Jialing Cai, Yueyang Liu, Tianyu Xu, Jingyu Yang, Chunfu Wu
Summary: This article discusses the role of oxytocin in treating drug addiction, including its effects on drug reward, stress responses, and social impairments. Studies have shown that oxytocin administration can alleviate drug-induced neurobehavioral changes and be beneficial in reducing substance use disorders of various drugs.
PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Neurosciences
Anees Bahji, Marlon Danilewitz, David Crockford
Summary: In the midst of the opioid epidemic, harm reduction-oriented approaches have gained attention. Some advocate for interventions that focus on prescribing pharmaceutical-grade psychoactive substances instead of illicit versions to mitigate fatal overdose risks. However, the evidence supporting this practice remains insufficient.
Article
Substance Abuse
Katie Witkiewitz, Elena R. Stein, Victoria R. Votaw, Kevin A. Hallgren, Benjamin C. Gibson, Cassandra L. Boness, Matthew R. Pearson, Stephen A. Maisto
Summary: This study aims to validate the utility of addiction cycle domains in predicting treatment outcomes and recovery among individuals with alcohol use disorder (AUD). The results showed that relief drinking/negative emotionality and reward drinking/incentive salience were significantly associated with treatment outcomes. Measurement of addiction cycle domains varied across different sociodemographic groups.
PSYCHOLOGY OF ADDICTIVE BEHAVIORS
(2023)
Review
Nutrition & Dietetics
Long T. Nguyen, Carol A. Pollock, Sonia Saad
Summary: The developmental programming hypothesis suggests that adverse environmental insults during critical developmental periods increase the risk of diseases in later life. Kidneys are susceptible to such insults, particularly due to peri-gestational nutrition, which affects kidney development and metabolism. Recent studies have identified oxidative stress, mitochondrial dysfunction, epigenetic modifications, and metabolic changes as potential novel pathways for therapeutic intervention.
Article
Medicine, General & Internal
Esther Pars, Joanne E. L. VanDerNagel, Boukje A. G. Dijkstra, Arnt F. A. Schellekens
Summary: This study explores the viability of using negative recovery capital (NRC) in individuals with substance use disorder (SUD), psychiatric comorbidities, and an intellectual disability. The study finds that all recovery domains are prevalent and relevant, influenced by critical life events, and individuals prioritize individual skill development during treatment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Nicholas Guenzel, Hongying Dai
Summary: The study analyzed the confidence levels of 12 American Indians undergoing Peer Recovery Coach training, showing an overall improvement in confidence post-training, particularly in specific PRC techniques. The findings provide insights for future training and may encourage further systematic analysis of the impact of PRC training.
Article
Substance Abuse
V. Manning, A. D. Roxburgh, M. Savic
Summary: Research suggests that peer support groups can enhance treatment effects and improve long-term recovery from alcohol and drug problems. However, these groups are rarely integrated into outpatient treatment programs, missing the opportunity for peer-to-peer learning and connection to others.
ADDICTION SCIENCE & CLINICAL PRACTICE
(2023)
Article
Psychology, Multidisciplinary
David Best, Arun Sondhi, Lorna Brown, Mulka Nisic, Gera E. Nagelhout, Thomas Martinelli, Dike van de Mheen, Wouter Vanderplasschen
Summary: This study reveals that being married or co-habiting during recovery is associated with greater recovery strengths and fewer barriers, as well as increased recovery capital. Having dependent children living with participants also shows similar positive associations, with a potential stronger effect for female participants. Additionally, having more people to rely on and a higher proportion of recovery peers in the social network are linked to increased recovery capital and self-reported growth.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Substance Abuse
Jina Sang, Rikki A. Patton, Insun Park
Summary: This qualitative study compared the perspectives of service users and professionals on current substance use disorders (SUD) services in Summit County, Ohio. The findings revealed both similarities and differences between the two groups on various themes, including the effectiveness of medication-assisted treatment, challenges in SUD recovery, and factors affecting treatment outcomes.
SUBSTANCE USE & MISUSE
(2022)
Article
Psychology, Multidisciplinary
Steven J. Foulis, Kailyn Rigby, Alex Loftus, Nikhil Satchidanand, David Holmes
Summary: Opioid addiction is a serious public health issue that has gained widespread attention. This paper explores the role of spirituality in overcoming opioid addiction and investigates which recovery strategies are most helpful from the patients' perspective. The study found that faith-based recovery programs were popular among patients, who relied on non-traditional means such as prayer and reading the Bible. Additionally, desires for recovery and family well-being were commonly requested topics for prayer.
CURRENT PSYCHOLOGY
(2023)
Article
Psychiatry
Hyoun S. Kim, Daniel S. Mcgrath, David C. Hodgins
Summary: The study aims to compare and identify the recovery processes associated with substitution and concurrent recovery in gambling disorder. The findings suggest that addiction substitution often occurs as a substitute coping mechanism, while concurrent recovery is driven by the mutual influence of different addictions. Negative emotional states are common during both addiction substitution and concurrent recovery.
JOURNAL OF BEHAVIORAL ADDICTIONS
(2023)
