In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases

Title
In Vivo Predictive Dissolution: Comparing the Effect of Bicarbonate and Phosphate Buffer on the Dissolution of Weak Acids and Weak Bases
Authors
Keywords
Dissolution, mathematical model, gastrointestinal, diffusion, physicochemical properties, transport, in vitro models, acid-base equilibria
Journal
JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 104, Issue 9, Pages 2894-2904
Publisher
Elsevier BV
Online
2015-05-16
DOI
10.1002/jps.24460

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