A validated liquid chromatography tandem mass spectrometry method for quantification of erlotinib, OSI-420 and didesmethyl erlotinib and semi-quantification of erlotinib metabolites in human plasma

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Title
A validated liquid chromatography tandem mass spectrometry method for quantification of erlotinib, OSI-420 and didesmethyl erlotinib and semi-quantification of erlotinib metabolites in human plasma
Authors
Keywords
LC–MS/MS, Human liver microsomes, Non-small cell lung cancer, EGFR, Tyrosine kinase inhibitor
Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 107, Issue -, Pages 186-195
Publisher
Elsevier BV
Online
2014-12-25
DOI
10.1016/j.jpba.2014.12.022

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