Article
Fisheries
Su -Mi Shin, Sajal Kole, Jehee Lee, Ji Sung Choi, Sung-Ju Jung
Summary: The study developed a chitosan microsphere (MS)-encapsulated vaccine for Miamiensis avidus and evaluated its protective efficacy in flounder. The results showed that the vaccine with a chitosan concentration of 0.05% provided moderate protection against the parasite. Additionally, using chitosan MS as an antigen carrier improved survival rates and enhanced specific antibody levels in the fish.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Sajal Kole, Su-Mi Shin, Ihn-Sil Kwak, Sung Hwoan Cho, Sung-Ju Jung
Summary: This study assessed the protective efficacy of a trivalent oral vaccine in olive flounder and found that the vaccine induced specific antibodies and upregulated immune genes, resulting in improved ability to combat pathogens.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Su-Mi Shin, Jae-Woong Lim, So Young Kang, Mi Kyeong Lee, Sung-Ju Jung
Summary: Research on lignum extract from lacquer tree showed promising results in preventing scuticociliatosis in olive flounder caused by the ciliate Miamiensis avidus. The optimized extract contained active compounds like gallic acid, fustin, and fisetin, which proved to be effective and safe in controlling the parasite without toxic effects.
Article
Immunology
Sajal Kole, Showkat Ahmad Dar, Su-Mi Shin, Hyeon-Jong Jeong, Sung-Ju Jung
Summary: Olive flounder is the most valuable aquaculture species in Korea, but faces serious disease problems in recent years. A newly developed vaccine shows good prophylactic effects against VHS, streptococcosis, and scuticociliatosis diseases.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Kun Yang, Xueshu Zhang, Zengyu Liu, Weiqun Lu
Summary: In animals, personalities have been found to be linked to behavioral traits, health and disease susceptibility, and welfare. This study examines the performance differences of flounder offspring with different personalities (OFDP). The offspring of bold individuals (OB) were found to be heavier and have higher survival rates compared to the offspring of shy individuals (OS). The study also analyzes the variability of microsatellites and their relationship with OFDP, and finds that certain microsatellite loci are correlated with growth, heat tolerance, and disease resistance. These findings contribute to olive flounder aquaculture and provide insights for fish personality selective breeding.
Article
Food Science & Technology
D. P. Nagahawatta, N. M. Liyanage, Thilina U. Jayawardena, H. H. A. C. K. Jayawardhana, Jae-Young Oh, K. K. Asanka Sanjeewa, Sang In Kang, You-Jin Jeon
Summary: The study found that digested flounder meat has the potential to promote skeletal muscle growth and can be used as a functional food ingredient.
Article
Immunology
Qian Li, Heng Chi, Xueyan Shi, Qiujie Gan, Roy Ambli Dalmo, Yuan-yuan Sun, Xiaoqian Tang, Jing Xing, Xiuzhen Sheng, Wenbin Zhan
Summary: This study introduced a new method for detecting ETs in the peritoneum of fish in vivo and indicated that ET formation is involved in the immune response at the early stage after intraperitoneal immunization to vaccines.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Environmental Sciences
Ping Han, Yingjie Qiao, Jiayi He, Xubo Wang
Summary: This study investigated the effects of temperature rise on the liver of Japanese flounder. The results showed that heat stress can cause tissue damage, inflammation, oxidative stress, and endoplasmic reticulum stress. These findings contribute to understanding the adaptive mechanisms of economic fish in the face of increasing water temperature caused by global warming.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Genetics & Heredity
Fan Yang, Saisai Liu, Jiangbo Qu, Quanqi Zhang
Summary: The Pomstna gene in Japanese flounder has been identified as a negative regulator of muscle growth and differentiation, and it operates through a different regulatory mechanism than Pomstnb. This study suggests that muscle proliferation and differentiation are not only regulated through the TGF-beta signaling pathway, but also through other unknown mechanisms.
Article
Environmental Sciences
Zhengrui Zhang, Yuezhong Liu, Wei Zhang, Xinxin Du, Jinxiang Liu
Summary: The study focuses on the diversity of opsins and their expression patterns in flatfishes, particularly in Japanese flounder. The research reveals that the visual system of Japanese flounder is adapted to a benthic environment through fine-tuning paralogous opsins and regulated expression. The study suggests that opsin repertoires optimize visual function under variable light environments through gene family duplications, differential expressions, and variations in maximum absorption wavelength (lambda max).
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Fisheries
W. K. M. Omeka, D. S. Liyanage, Sukkyoung Lee, Chaehyeon Lim, Hyerim Yang, W. M. Gayashani Sandamalika, H. M. V. Udayantha, Gaeun Kim, Subothini Ganeshalingam, Taehyug Jeong, Seong-Rip Oh, Seung-Hwan Won, Hyoung-Bum Koh, Mun-Kwan Kim, David B. Jones, Cecile Massault, Dean R. Jerry, Jehee Lee
Summary: Traits linked to growth performance in farmed fish are important for profitability in aquaculture. A genome-wide association study (GWAS) on olive flounder identified several single nucleotide polymorphisms (SNPs) associated with growth traits. These findings contribute to understanding the molecular basis of growth regulation and promote the use of SNP-based genomic selection in flounder culture.
Article
Immunology
Yanbo Hao, Xiaoqian Tang, Jing Xing, Xiuzhen Sheng, Heng Chi, Wenbin Zhan
Summary: The Fc receptor plays a critical role in mediating the phagocytosis and bactericidal activity of IgM(+) B lymphocytes in flounder. It increases phagocytosis rates and affects intracellular reactive oxygen species levels. Additionally, blocking Fc receptor or Fc fragment of IgM reduces phagocytosis rates in mIgM(+) B lymphocytes.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Multidisciplinary Sciences
Takahiro Ikari, Yukihiro Furusawa, Yoshiaki Tabuchi, Yusuke Maruyama, Atsuhiko Hattori, Yoichiro Kitani, Kenji Toyota, Arata Nagami, Jun Hirayama, Kazuki Watanabe, Atsushi Shigematsu, Muhammad Ahya Rafiuddin, Shouzo Ogiso, Keisuke Fukushi, Kohei Kuroda, Kaito Hatano, Toshio Sekiguchi, Ryotaro Kawashima, Ajai K. Srivastav, Takumi Nishiuchi, Akihiro Sakatoku, Masa-aki Yoshida, Hajime Matsubara, Nobuo Suzuki
Summary: Deep ocean water (DOW) promotes the growth of marine organisms and reduces stress in Japanese flounder. The regulation of gene expression and the activation of osteoblasts in fish scales play a role in the cortisol-reducing effect. Kynurenine, an indole component in DOW, facilitates Calcitonin production by osteoblasts and leads to a decrease in cortisol concentration.
SCIENTIFIC REPORTS
(2023)
Article
Environmental Sciences
Hongmei Zhang, Zhaobin Xu, Junxiao Xu, Zhenlin Wei, Zhiyi Shi
Summary: This study cloned the Japanese flounder Drosha gene, which is highly expressed in the brain and to a lesser extent in muscle. Knockdown experiments showed that Drosha plays a crucial role in the development and metamorphosis of the Japanese flounder.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Environmental Sciences
Jun Wang, Xuan Li, Peng Li, Lianxu Li, Lingchao Zhao, Shaoguo Ru, Dahai Zhang
Summary: This study found that microplastics enhance the thyroid-disrupting effects of polychlorinated biphenyls (PCBs), further emphasizing the risk of microplastics and thyroid-disrupting chemicals on marine organisms.
MARINE POLLUTION BULLETIN
(2022)
Article
Virology
Jae-Ok Kim, Wi-Sik Kim, Myung-Joo Oh
Article
Fisheries
Syed Shariq Nazir Qadiri, Soo-Jin Kim, Rahul Krishnan, Sajal Kole, Myung-Joo Oh
Article
Fisheries
K. U. Shyam, Ha-Na Jeong, Myung-Joo Oh, Choon-Sup Kim, Wi-Sik Kim
Article
Fisheries
Rahul Krishnan, Jong-Oh Kim, Syed Shariq Nazir Qadiri, Jae-Ok Kim, Myung-Joo Oh
FISH & SHELLFISH IMMUNOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Jun-Young Song, Ayako Casanova-Nakayama, Anja-Maria Moeller, Shin-Ichi Kitamura, Kei Nakayama, Helmut Segner
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Virology
Soo-Jin Kim, Myung-Joo Oh
Article
Fisheries
Rahul Krishnan, Syed Shariq Nazir Qadiri, Jae-Ok Kim, Myung-Joo Oh
Summary: Initial NNV infection through intraperitoneal injection resulted in acute shedding, while varying levels of infection in cohabitation challenge led to different mortality rates. Peak viral shedding rate differed significantly among groups with different infection levels.
Article
Virology
Si-Woo Kim, Soo-Jin Kim, Myung-Joo Oh
Summary: Immunization at low temperature with NNV in sevenband grouper resulted in increased resistance against NNV infection, leading to lower mortality rates and decreased disease symptoms.
Article
Fisheries
Kyoung-Hui Kong, Ha-Na Jeong, K. U. Shyam, Myung-Joo Oh, Choon-Sup Kim, Hyoung Jun Kim, Wi-Sik Kim
Summary: The LFIA technology developed with seven anti-VHSV antibodies allows for rapid and specific detection of VHSV in olive flounders, with a high sensitivity and specificity. The field validation of the assay showed a diagnostic effectiveness of 97.3% with a specificity of 100% and sensitivity of 93.9%.
Article
Fisheries
Rahul Krishnan, Yo-Seb Jang, Myung-Joo Oh
Summary: In this study, the researchers investigated the effect of beta-glucan on the immune response against nervous necrosis virus (NNV). They found that beta-glucan enhanced the macrophages' ability to combat NNV infection and increased survival rates in infected fish. The findings suggest that beta-glucan has potential applications in vaccination strategies.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Rahul Krishnan, Yo-Seb Jang, Jong-Oh Kim, Myung-Joo Oh
Summary: The study demonstrated that the survival following challenges at different temperatures was due to stable and sustained activation of the immune response, but rechallenge at optimal temperature showed hyperactivation of the immune system. The mortality pattern observed is correlated with cytokine storm and suggests a possible role of NK cells and microglia in mediating antiviral immune response at different temperatures.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Jun-Young Song, Shin-Ichi Kitamura, Myung-Joo Oh, Kei Nakayama
Summary: The combined treatment of heavy oil exposure and virus infection in Japanese flounder led to increased mortality. Heavy oil exposure may promote virus replication, leading to higher mortality in the co-treated group. Gene expression profiling showed lower expression of antiviral activity-related genes in the co-treated group. These results help explain the high virus titers in fish treated with both stressors.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Rahul Krishnan, Rahul Rajendran, Yo-Seb Jang, Jong-Oh Kim, Su-Young Yoon, Myung-Joo Oh
Summary: NLRC3, a unique regulatory NLR, is involved in the modulation of cellular processes and inflammatory responses. In this study, the function of NLRC3 in the context of nervous necrosis virus (NNV) infection in seven band grouper was characterized. NLRC3 was found to enhance NNV replication and attenuate interferon responses, while positively regulating inflammasome response and pro-inflammatory gene expression. NLRC3 also negatively regulates the PI3K-mTOR axis and activates the cellular autophagic response. These findings provide important insights into the regulatory mechanism of NLRC3 in the immune response following NNV infection.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Tetsuya Yanagida, Kei Nakayama, Tomoo Sawada, Miho Honjo, Shoko Murakami, Takaji Iida, Euichi Hirose, Shin-Ichi Kitamura
Summary: This study demonstrates for the first time that the innate immunity in the blood plasma and hemolymph of Halocynthia roretzi plays a protective role against the infection of Azumiobodo hoyamushi, preventing its invasion into internal tissues.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Review
Fisheries
K. U. Shyam, Hwi-Jin Kim, Sajal Kole, Myung-Joo Oh, Choon-Sup Kim, Do-Hyung Kim, Wi-Sik Kim
Summary: Lateral flow immunoassays (LFIAs) are user-friendly and cost-effective point-of-care detection systems widely used in aquaculture for pathogen detection. This review article summarizes 22 LFIA detection devices used in aquaculture, providing valuable baseline data for the development of new LFIA devices targeting significant pathogens.