Article
Computer Science, Artificial Intelligence
Dandan Ning, Huiyong Geng, Jingming Guan, Sijia Zhang, Shuang Wang, Shuang Li, Shizhu Jin
Summary: A study shows that using the Colonoscope Roaming System (CRS) as an e-learning tool improves the performance of beginner colonoscopists in posttest scores and actual colonoscopy examination compared to traditional teaching methods.
PEERJ COMPUTER SCIENCE
(2023)
Article
Integrative & Complementary Medicine
Alessandro Tani, Gennaro Tartarisco, Guido Vagheggini, Carla Vaccaro, Serena Campana, Francesco Tomaiuolo
Summary: This study demonstrates that Binaural Beats (BB) is an effective and safe method for reducing pain and improving patient comfort during colonoscopy. The non-pharmacological, non-invasive, inexpensive, and simple nature of BB makes it a favorable option for non-sedated patients undergoing colonoscopy.
COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
(2022)
Article
Gastroenterology & Hepatology
Mao Matsubayashi, Taku Kobayashi, Shinji Okabayashi, Masaru Nakano, Shintaro Sagami, Ryo Ozaki, Hiroki Kiyohara, Hiromu Morikubo, Kunio Asonuma, Yusuke Miyatani, Shin Maeda, Toshifumi Hibi
Summary: CSUC score can predict relapse within one year in UC patients during clinical remission, especially when used 6 months after induction treatment.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Stefan Schreiber, Shomron Ben-Horin, Jaroslaw Leszczyszyn, Robert Dudkowiak, Adi Lahat, Beata Gawdis-Wojnarska, Aldis Pukitis, Marek Horynski, Katalin Farkas, Jaroslaw Kierkus, Maciej Kowalski, Sang Joon Lee, Sung Hyun Kim, Jee Hye Suh, Mi Rim Kim, Seul Gi Lee, Byong Duk Ye, Walter Reinisch
Summary: This study demonstrated the pharmacokinetic noninferiority of CT-P13 SC to CT-P13 IV, with comparable clinical remission rates between the two formulations.
Article
Nutrition & Dietetics
Anna Pietrzak, Marcin Banasiuk, Mariusz Szczepanik, Agnieszka Borys-Iwanicka, Tomasz Pytrus, Jaroslaw Walkowiak, Aleksandra Banaszkiewicz
Summary: This study evaluated the effectiveness of oral sodium butyrate as an add-on to standard therapy in children and adolescents with newly diagnosed IBD. The results showed that a 12-week supplementation with sodium butyrate did not show efficacy in these patients.
Article
Gastroenterology & Hepatology
Shomron Ben-Horin, Ofir Har-Noy, Konstantinos H. Katsanos, Xavier Roblin, Minhu Chen, Xiang Gao, Doron Schwartz, Jae Hee Cheon, Monica Cesarini, Daniela Bojic, Marijana Protic, Angeliki Theodoropoulou, Heba Abu-Kaf, Tal Engel, Jian Tang, Pauline Veyrard, Xiaoqing Lin, Ren Mao, Dimitrios Christodoulou, Konstantinos Karmiris, Tamara Knezevic-Ivanovski
Summary: In this randomized controlled trial, the combination of mesalamine with corticosteroids did not show superior efficacy compared to corticosteroids alone in hospitalized patients with acute severe ulcerative colitis (ASUC). However, there was a potential indication that the need for biologics was reduced in the mesalamine group within 90 days.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Mark Lowenberg, Adriaan Volkers, Sara van Gennep, Aart Mookhoek, Nahid Montazeri, Esme Clasquin, Marjolijn Duijvestein, Adriaan van Bodegraven, Svend Rietdijk, Jeroen Jansen, Dirk van Asseldonk, Esmerij van der Zanden, Marcel Dijkgraaf, Rachel West, Nanne de Boer, Geert D'Haens
Summary: This study showed that mercaptopurine was more effective than placebo in treating ulcerative colitis (UC) and achieving clinical, endoscopic, and histological improvements after one year of treatment. However, there were more adverse events in the mercaptopurine group.
JOURNAL OF CROHNS & COLITIS
(2023)
Article
Gastroenterology & Hepatology
Su Bum Park, Seong-Jung Kim, Jun Lee, Yoo Jin Lee, Dong Hoon Baek, Geom Seog Seo, Eun Soo Kim, Sang-Wook Kim, So Yeong Kim
Summary: Sigmoidoscopy can be considered a sufficient substitute for colonoscopy in evaluating disease activity in ulcerative colitis, as they show a high concordance rate. However, colonoscopy should still be considered in patients with previous extensive colitis.
BMC GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Toshihiro Kita, Sinya Ashizuka, Naoki Ohmiya, Takayuki Yamamoto, Takanori Kanai, Satoshi Motoya, Fumihito Hirai, Hiroshi Nakase, Tomohiko Moriyama, Masanao Nakamura, Yasuo Suzuki, Shuji Kanmura, Taku Kobayashi, Hidehisa Ohi, Ryoichi Nozaki, Keiichi Mitsuyama, Shojiro Yamamoto, Haruhiko Inatsu, Koji Watanabe, Toshifumi Hibi, Kazuo Kitamura
Summary: This multicenter, double-blind, placebo-controlled phase-2a clinical trial aimed to evaluate the efficacy and safety of AM in patients with steroid-resistant UC. Results showed that the high-dose AM group achieved significant reductions in Mayo scores and higher rates of clinical remission at 8 weeks.
JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Surgery
Peiwen Li, Bin Ma, Shulei Gong, Xinyu Zhang, Wenya Li
Summary: Dynamic position changes during colonoscope withdrawal increased the total ADR, however, no obvious increase was found in the total PDR. The withdrawal time was not significantly prolonged with dynamic position changes. Subgroup analysis showed that the ADR and PDR in the transverse colon were obviously improved with dynamic position changes.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Essi K. Karjalainen, Laura Renkonen-Sinisalo, Reetta Satokari, Harri Mustonen, Ari Ristimaki, Perttu Arkkila, Anna H. Lepisto
Summary: The fecal microbiota transplantation treatment did not show efficacy in treating chronic pouchitis, however the safety profile was good. Among patients who were using continuous antibiotics before the study, the relapse-free survival was shorter in the intervention group.
INFLAMMATORY BOWEL DISEASES
(2021)
Article
Gastroenterology & Hepatology
Thomas C. Mules, Brittany Lavender, Kate Maclean, Francesco Vacca, Sophia-Louise Noble, Bibek Yumnam, Tama Te Kawa, Alissa Cait, Jeffry Tang, David O'Sullivan, Olivier Gasser, James Stanley, Graham Le Gros, Mali Camberis, Stephen Inns
Summary: This pilot study demonstrated that a full-scale randomized control trial investigating hookworm therapy as maintenance treatment in patients with ulcerative colitis is feasible, safe, and well-tolerated.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Gastroenterology & Hepatology
Amy L. Lightner, Sarah Vogler, John McMichael, Xue Jia, Miguel Regueiro, Taha Qazi, Scott R. Steele
Summary: While UC patients were more likely to have neoplasia detected during colonoscopy, the rates of progression from LGD and HGD to adenocarcinoma were equivalent in UC and CD, suggesting consistent endoscopic surveillance strategies for all IBD patients.
JOURNAL OF CROHNS & COLITIS
(2021)
Article
Gastroenterology & Hepatology
Rebecca J. Birch, Nicholas Burr, Venkataraman Subramanian, Jim P. Tiernan, Mark A. Hull, Paul Finan, Azmina Rose, Matthew Rutter, Roland Valori, Amy Downing, Eva J. A. Morris
Summary: This study investigated the epidemiology and outcomes of inflammatory bowel disease-associated colorectal cancer (IBD-CRC). It found that IBD patients have a higher risk of developing CRC, are diagnosed at a younger age, and have worse outcomes compared to sporadic CRC. Further research is needed to understand the reasons behind these differences and inform screening, surveillance, and treatment strategies for this high-risk group.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Editorial Material
Medicine, General & Internal
Elizabeth Chen, James W. Li, Lai M. Wang, Khin Y. Lwin, Chin K. Tan, Jeannie Ong, Tiing L. Ang
Summary: Misdiagnosis of intestinal schistosomiasis is common due to its similarity with ulcerative colitis. Endoscopy helps in diagnosis, but findings are often non-specific. Correlation with histopathological features and the presence of schistosome ova within the lamina propria are crucial for accurate diagnosis.