Article
Gastroenterology & Hepatology
Manasi Agrawal, Giulia Corn, Sarita Shrestha, Nete Munk Nielsen, Morten Frisch, Jean-Frederic Colombel, Tine Jess
Summary: The study estimated the relative risk of IBD among first-generation and second-generation immigrants in Denmark, finding that the risk of IBD was lower for first-generation immigrants and increased with longer duration of stay in Denmark. The relative risk of IBD was lower only among women for second-generation immigrants.
Article
Medicine, General & Internal
Yun-Hsiu Hsieh, Chi-Hsiang Chung, Chien-An Sun, Po-Huang Chen, Yi-Hao Chen, Chang-Min Liang, Jiann-Torng Chen, Wu-Chien Chien, Ching-Long Chen
Summary: Patients with inflammatory bowel disease (IBD) have a higher risk of developing optic neuritis (ON) compared to those without IBD. ON occurs more frequently in IBD patients aged between 30 and 39 years, with comorbidities including neuromyelitis optica (NMO), acute disseminated encephalomyelitis (ADEM) and systemic lupus erythematosus (SLE). Other factors besides anti-tumor necrosis factor alpha treatment for IBD are more likely associated with the development of ON.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Jakob Ronnow Sand, Frederikke Schonfeldt Troelsen, Erzsebet Horvath-Puho, Victor W. Henderson, Henrik Toft Sorensen, Rune Erichsen
Summary: Inflammatory bowel disease (IBD) is associated with a slightly increased risk of dementia, particularly frontotemporal dementia in patients with Crohn's disease (CD). Frequent healthcare system contacts by IBD patients may play a role in this association.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Gastroenterology & Hepatology
Nishani Jayasooriya, Jonathan Blackwell, Sonia Saxena, Alex Bottle, Irene Petersen, Hanna Creese, Matthew Hotopf, Richard C. G. Pollok
Summary: This study found that the use of antidepressants among individuals diagnosed with inflammatory bowel disease (IBD) has been increasing over the years. However, a majority of patients did not adhere to the recommended treatment duration according to international guidelines. Younger patients were more likely to discontinue antidepressant treatment earlier.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Gastroenterology & Hepatology
M. Ellen Kuenzig, Alain Bitton, Matthew W. Carroll, Gilaad G. Kaplan, Anthony R. Otley, Harminder Singh, Geoffrey C. Nguyen, Anne M. Griffiths, Therese A. Stukel, Laura E. Targownik, Jennifer L. Jones, Sanjay K. Murthy, Jeffrey D. McCurdy, Charles N. Bernstein, Lisa M. Lix, Juan Nicolas Pena-Sanchez, David R. Mack, Kevan Jacobson, Wael El-Matary, Trevor J. B. Dummer, Stephen G. Fung, Sarah Spruin, Zoann Nugent, Divine Tanyingoh, Yunsong Cui, Christopher Filliter, Stephanie Coward, Shabnaz Siddiq, Eric Benchimol
Summary: Children with inflammatory bowel disease have a significantly higher risk of venous thromboembolism compared to those without the disease, although the absolute risk is low. The incidence rate observed in this study was higher than previously described in pediatric literature.
JOURNAL OF CROHNS & COLITIS
(2021)
Article
Medicine, Research & Experimental
Kuan-Chieh Tu, Ru-Yi Yu, Yu-Hsuan Lin, Chih-Chiang Chien, Chin-Li Lu
Summary: This study aimed to examine the bidirectional association between infectious gastroenteritis (IGE) and inflammatory bowel disease (IBD). By analyzing data from the Taiwan National Health Insurance Research Database, it was found that there is a bidirectional association between IGE and IBD. IBD patients were more likely to have been exposed to IGE within 6 months to 5 years before diagnosis compared to non-IBD controls. Additionally, the risk of subsequent IGE was higher in IBD patients after diagnosis.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Ga Hee Kim, Yeong Chan Lee, Tae Jun Kim, Eun Ran Kim, Sung Noh Hong, Dong Kyung Chang, Young-Ho Kim
Summary: The study found that patients with inflammatory bowel disease (IBD) have a higher risk of neurodegenerative diseases compared to the non-IBD population. IBD patients aged 40-65 had a higher risk of Parkinson's disease, while patients aged 65 and above had an increased risk of Alzheimer's disease.
JOURNAL OF CROHNS & COLITIS
(2022)
Article
Gastroenterology & Hepatology
Adam S. Faye, Kristine Hojgaard Allin, Aske T. Iversen, Manasi Agrawal, Jeremiah Faith, Jean-Frederic Colombel, Tine Jess
Summary: This study used Danish nationwide registries to investigate the association between antibiotic exposure and the risk of inflammatory bowel disease (IBD). The results showed that antibiotic exposure was associated with an increased risk of IBD, especially in individuals aged 40 years and older. The risk was highest within 1-2 years after antibiotic exposure and with the use of antibiotics targeting gastrointestinal pathogens.
Article
Gastroenterology & Hepatology
Jordan E. Axelrad, Ola Olen, Michael C. Sachs, Rune Erichsen, Lars Pedersen, Jonas Halfvarson, Johan Askling, Anders Ekbom, Henrik Toft Sorensen, Jonas F. Ludvigsson
Summary: Crohn's disease patients are at increased risk of developing small bowel cancer and dying from it, with higher risks for recently diagnosed patients and those with childhood-onset, ileal, and stricturing CD. However, the absolute risks are low overall.
Article
Gastroenterology & Hepatology
Jonathan Blackwell, Sonia Saxena, Irene Petersen, Matthew Hotopf, Hanna Creese, Alex Bottle, Christopher Alexakis, Richard C. Pollok
Summary: Depression alone is not associated with subsequent development of IBD, but when accompanied by GI symptoms, it may indicate a risk for IBD.
Article
Oncology
Huimin Zhang, Mengmeng Zhang, Xuanfu Chen, Mingyue Guo, Runing Zhou, Hong Lv, Yue Li, Bei Tan, Ji Li, Hui Xu, Weiyang Zheng, Hong Yang, Jiaming Qian
Summary: The increased risks of multiple cancers are particularly prominent in Chinese IBD patients, especially digestive cancers, thyroid cancer, and hematological malignancies, emphasizing the need for more targeted guidance for cancer monitoring.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Multidisciplinary Sciences
Tawnya M. Hansen, Zoann Nugent, Charles N. Bernstein, N. Jewel Samadder, Sanjay K. Murthy, Harminder Singh
Summary: The risk of death following CRC diagnosis is not affected by a diagnosis of IBD in recent years. There is a high proportion of post colonoscopy CRC among IBD-CRC patients, which has remained unchanged over the years and requires detailed root-cause analysis and interventions.
Article
Gastroenterology & Hepatology
Mohamed Attauabi, Anja Poulsen, Klaus Theede, Natalia Pedersen, Lone Larsen, Tine Jess, Malte Rosager Hansen, Marianne Kajbaek Verner-Andersen, Kent Haderslev, Anders Berg Lodrup, Akbar Molazahi, Anders Neumann, Abdel Wase, Jakob Benedict Seidelin, Johan Burisch
Summary: Patients with immune-mediated inflammatory diseases, including IBD, were less susceptible to COVID-19 compared to patients without such diseases, and use of immunosuppressive therapies or disease activity of IBD did not affect the disease course of COVID-19.
JOURNAL OF CROHNS & COLITIS
(2021)
Article
Gastroenterology & Hepatology
Kinga Kowalska-Duplaga, Anita Gawlik-Scislo, Elzbieta Krzesiek, Elzbieta Jarocka-Cyrta, Izabella Lazowska-Przeorek, Mariusz Duplaga, Aleksandra Banaszkiewicz
Summary: The study found that children with IBD and their parents exhibited poor knowledge regarding the side effects of steroid therapy, the role of surgical treatment in IBD, dietary restrictions, and risks associated with herbal medicines. Patients' IBD-KID scores were associated with patient sex and age, while parents' scores were related to patient age and treatment with immunosuppressive agent. The study suggests the importance of implementing better education programs for patients and parents.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Ophthalmology
Tzu-Chen Lo, Yu-Yen Chen, Hsin-Hua Chen
Summary: The study revealed that patients with uveitis are at a significantly higher risk of developing inflammatory bowel disease (IBD) compared to individuals without uveitis. Furthermore, uveitis was found to be significantly associated with an increased risk of Crohn's disease but not ulcerative colitis.
Article
Chemistry, Analytical
Monika Thakur, Harminder Singh, Jaspreet Kaur Rajput, Rupesh Kumar
Summary: In this study, a novel sunlight-active ternary magnetic nano-photocatalyst GCNI was fabricated and characterized. The efficacy of GCNI for RhB removal was investigated and the mechanism of dye removal and degradation was discovered. The results showed that GCNI had high efficiency in dye removal, easy magnetic separation, and excellent reusability.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2023)
Article
Plant Sciences
Piyanan Pipatsitee, Cattarin Theerawitaya, Rujira Tiasarum, Thapanee Samphumphuang, Harminder Pal Singh, Avishek Datta, Suriyan Cha-um
Summary: Drought is a major factor restricting maize productivity, especially in rainfed areas. This study investigated physiological adaptation strategies and sugar-related gene expression levels in three maize genotypes with different drought tolerance abilities at the seedling stage. The research found that drought-tolerant maize genotypes utilize soluble sugars to maintain leaf greenness and photosynthetic efficiency.
Article
Surgery
Garrett G. R. J. Johnson, Olivia Hershorn, Harminder Singh, Jason Park, Ramzi M. Helewa
Summary: This study found a 22.6% rate of sampling errors in flexible sigmoidoscopy for colorectal cancer patients, leading to delays in surgical care. Following sampling errors, the time to surgery was 1.4 times longer compared to correct positive biopsies.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Olivia Hershorn, Jason Park, Harminder Singh, Kathleen Clouston, Ashley Vergis, Ramzi M. Helewa
Summary: A study conducted in a high-volume Canadian tertiary centre found that 29% of colorectal surgery patients required repeat preoperative endoscopy. Factors such as male sex, lesions located in the left colon, rectosigmoid, and rectum were associated with increased odds of undergoing repeat preoperative endoscopy. Tattooing suspicious lesions significantly reduced the likelihood of repeat preoperative endoscopy.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Plant Sciences
Kulwinder Kaur Mehal, Amarpreet Kaur, Harminder Pal Singh, Daizy R. Batish
Summary: The study found that aqueous extracts from the fresh foliage and leaf litter of Verbesina encelioides have allelopathic effects on co-occurring plant species, inhibiting their growth and photosynthetic processes. The extracts contain various allelochemicals, supporting the novel weapon hypothesis.
Article
Green & Sustainable Science & Technology
Alpy Sharma, Sanjay Kr Uniyal, Daizy Rani Batish, Harminder P. Singh
Summary: The present study examined the fuelwood use and knowledge variations among the Bhangalis, a resident community in Chhota Bhangal, Himachal Pradesh. The findings revealed that the number of fuelwood species known by the Bhangalis was significantly different from the ones they actually used. The study also found variations in fuelwood knowledge based on gender, age, and family size.
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2023)
Article
Psychology, Developmental
Magdalena Janus, Julia Ryan, Molly Pottruff, Caroline Reid-Westoby, Marni Brownell, Teresa Bennett, Catherine S. Birken, Eric Duku, Mark A. Ferro, Barry Forer, Stelios Georgiades, Jan Willem Gorter, Martin Guhn, Jonathon Maguire, Heather Manson, Jacqueline Pei, Rob Santos, Robert J. Coplan
Summary: Despite being a prevalent mental health problem, there is little data on the pervasiveness and levels of anxiety symptoms in kindergarteners. This study collected data from Canada over a span of 11 years and found that highly anxious children were more likely to be male, have English/French as a second language, and have special needs designation. Furthermore, highly anxious children were more likely to score below the 10th percentile in physical, social, language/cognitive, and communication domains.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Gastroenterology & Hepatology
Mariam Narous, Zoann Nugent, Harminder Singh, Charles N. Bernstein
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Clinical Neurology
Michael Zhang, James Zhou, Benjamin Dirlikov, Tene Cage, Marco Lee, Harminder Singh
Summary: This study examines the impact of COVID-19 restrictions on neurosurgical procedures and provides guidance for resource management in the future. The results show a rebound in spinal surgeries after the restrictions were lifted, while cranial surgeries also increased during the pandemic.
JOURNAL OF CLINICAL NEUROSCIENCE
(2022)
Article
Gastroenterology & Hepatology
M. Ellen Kuenzig, Eric I. Benchimol, Charles N. Bernstein, Alain Bitton, Matthew W. Carroll, Anne M. Griffiths, Gilaad G. Kaplan, Geoffrey C. Nguyen, Anthony R. Otley, Therese A. Stukel, Trevor J. B. Dummer, Wael El-Matary, Kevan Jacobson, Jennifer L. Jones, Lisa M. Lix, David R. Mack, Sanjay K. Murthy, Juan-Nicolas Pena-Sanchez, Laura E. Targownik, Stephen G. Fung, Sarah Spruin, Stephanie Coward, Yunsong Cui, Christopher Filliter, Zoann Nugent, Shabnaz Siddiq, Harminder Singh
Summary: This population-based study compared the risk of hospitalization with Clostridioides difficile infection (CDI) in children with and without inflammatory bowel disease (IBD). The findings showed that children with IBD had a significantly higher incidence of CDI during hospitalization compared to children without IBD. Screening for CDI should be conducted for symptomatic children with IBD who are hospitalized.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
(2022)
Article
Plant Sciences
Cattarin Theerawitaya, Kanyaratt Supaibulwatana, Rujira Tisarum, Thapanee Samphumphuang, Daonapa Chungloo, Harminder Pal Singh, Suriyan Cha-Um
Summary: Nitrogen is an essential nutrient for plant growth and development, especially in rice production. This study investigated the morpho-physiological characteristics and expression level of nitrogen assimilation in different rice genotypes under different nitrogen conditions. The results showed that nitrogen deficiency inhibited rice seedling growth and reduced grain yield.
Article
Social Sciences, Interdisciplinary
Jennifer E. Enns, Marni Brownell, Hera J. M. Casidsid, Mikayla Hunter, Anita Durksen, Lorna A. Turnbull, Nathan C. Nickel, Karine Levasseur, Myra J. Tait, Scott Sinclair, Selena Randall, Amy Freier, Colette Scatliff, Emily Brownell, Aine Dolin, Nora Murdock, Alyson Mahar, Stephanie Sinclair, SPECTRUM Partnership
Summary: In Canadian society, there is a lack of coordination and collaboration between departments, sectors, and organizations in the planning and implementation of social services. This can result in poor outcomes and wasted resources when the needs of individuals are not addressed. To address this issue, the SPECTRUM Partnership was formed in 2018, bringing together community organizations, government, and academia to conduct research and evaluation on social programs and systems.
GATEWAYS-INTERNATIONAL JOURNAL OF COMMUNITY RESEARCH AND ENGAGEMENT
(2023)
Letter
Surgery
Julie Lee, Harminder Singh, Kathleen Decker, Ramzi Helewa, Marylise Boutros, Jason Park
BRITISH JOURNAL OF SURGERY
(2022)
Article
Primary Health Care
Viola Antao, Roland Grad, Guylene Theriault, James A. Dickinson, Olga Szafran, Harminder Singh, Raphael Rezkallah, Earle Waugh, Neil R. Bell
CANADIAN FAMILY PHYSICIAN
(2022)
Article
Primary Health Care
Viola Antao, Roland Grad, Guylene Theriault, James A. Dickinson, Olga Szafran, Harminder Singh, Raphael Rezkallah, Earle Waugh, Neil R. Bell
CANADIAN FAMILY PHYSICIAN
(2022)
Article
Pediatrics
Tarun Aurora, Audrey Cole, Parul Rai, Paul Lavoie, Carrie Mcivor, Lisa M. Klesges, Guolian Kang, Janaka S. S. Liyanage, Heather M. Brandt, Jane S. Hankins
Summary: This study evaluated the effectiveness of a vaccine strategy bundle in increasing HPV vaccine initiation and completion rates in a specialty clinic setting. By implementing the bundle, which included staff education, provider incentives, offering vaccines in clinics, and verifying vaccine completion, the clinic successfully improved HPV vaccine initiation and completion rates among sickle cell disease patients.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nienke M. Halbmeijer, Wes Onland, Jeroen Dudink, Filip Cools, Anne Debeer, Anton H. van Kaam, Manon J. N. L. Benders, Niek E. van der Aa
Summary: In ventilated infants born preterm, high dose systemic hydrocortisone initiated between 7 and 14 days after birth did not have a significant impact on brain development.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Katherine Melton, Jianfang Liu, Hossein Sadeghi, Maureen George, Arlene Smaldone
Summary: This study aims to identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF) patients. The study findings highlight the importance of CF RISE program engagement and reducing gaps in care for improving the transition of adolescents and young adults with CF.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Laura A. Duckworth, Kimberly A. Sutton, Nurmohammad Shaikh, Jinli Wang, Carla Hall-Moore, Lori R. Holtz, Phillip I. Tarr, Ronald C. Rubenstein
Summary: The study tested the usefulness of various biomarkers as indicators of gut dysfunction in cystic fibrosis (CF) and investigated the repeatability of these measures in individuals over short periods and their correlation with clinical outcomes. The results showed that elevated levels of fLcn2 in individuals with CF may predict worsened pulmonary function.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Lindsey Haack, Nikkan Das, Arvind Hoskoppal, Mark Debrunner, Tarek Alsaied, Gaurav Arora
Summary: RAE on ECG has a low positive predictive value for RAE on echocardiogram in previously healthy young patients. The highest yield for RAE on echocardiogram was observed in patients who were <1 year of age, had RAE in the anterior precordial leads, or displayed right ventricular hypertrophy on ECG.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael A. Padula, Khatija Naing, Tara L. Wenger, Irfan Ahmad, Carl H. Coghill, K. Taylor Wild, S. Alex Rottgers, Cory M. Resnick, Jeffrey Goldstein, Zarmina Ehsan, Donna Watkins, Nicole Deptula, Kuan-Chi Lai, Janet Lioy, Semsa Gogcu, Christopher M. Cielo
Summary: This study describes the spectrum of disease and burden of care in infants with congenital micrognathia. The results show that these infants commonly require surgical intervention and tube feedings, and disparities based on race and among centers were identified.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael P. Fundora, Manvitha Kalicheti, Guantao Zhao, Kevin O. Maher, Nicoleta Serban
Summary: This study investigated the variation of outpatient opioid prescribing in postoperative pediatric cardiac patients across the US. The results showed that there were significant differences in opioid prescribing by race, ethnicity, sex, and region.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Jia Guo, Brooklyn J. Fraser, Leigh Blizzard, Michael D. Schmidt, Terence Dwyer, Alison J. Venn, Costan G. Magnussen
Summary: There is a correlation between childhood and adulthood cardiorespiratory fitness.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Editorial Material
Pediatrics
Kanwaljit Singh, John Concato, Jonathan M. Davis
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Yaxing Meng, Harri Niinikoski, Suvi P. Rovio, Brooklyn J. Fraser, Feitong Wu, Antti Jula, Tapani Ronnemaa, Jorma S. A. Viikari, Olli T. Raitakari, Katja Pahkala, Costan G. Magnussen
Summary: This 26-year study shows a correlation between early-life non-HDL-C levels and future levels. Early dietary counseling can reduce the risk of high pediatric non-HDL-C, emphasizing the importance of early interventions in preventing cardiovascular risks.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kelsey A. B. Gastineau, Rebecca Bell, Allison Hanes, Sandra Mckay, Eric Sigel, Filoteia Popescu, Evan C. Sommer, Shari Barkin
Summary: This study aimed to assess the self-reported counseling outcomes for a firearm safe storage counseling training program provided by the American Academy of Pediatrics. The results demonstrated significant improvement in counseling self-efficacy and frequency one month after the training.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kathryn E. K. Berlin, William Scott, Sara Dawson, David Brousseau, Joanne M. Lagatta
Summary: This prospective cohort study aimed to investigate the impact of bronchopulmonary dysplasia (BPD) on the health-related quality of life (HRQL) of infants from NICU hospitalization to one year post-discharge. The study found that lower HRQL during NICU stay was associated with earlier gestational age, postnatal corticosteroid usage, outborn status, and gastrostomy tube placement. Lower HRQL at 3 and 12 months post-discharge was associated with readmissions, home oxygen use, parent-reported difficulty breathing, lower developmental scores, and not playing with other children. Most parents reported similar or improved HRQL after discharge, but parents of infants with respiratory symptoms experienced less improvement. Efforts to improve parent HRQL should focus on respiratory symptoms and social isolation.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Garett J. Griffith, Alan P. Wang, Robert I. Liem, Michael R. Carr, Tyler Corson, Kendra Ward
Summary: This study developed reference values for cardiorespiratory fitness in children aged 6-18 years without underlying heart disease, measured by peak oxygen uptake and treadmill time. Fitness levels increased with age in males but not females. Males generally exhibited higher fitness levels compared to females in the same age groups.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
David S. Liu, Patricia Miller, Anna Rothenberg, Carley Vuillermin, Peter M. Waters, Andrea S. Bauer
Summary: This study aims to determine if children with elbow flexion contracture (EFC) caused by brachial plexus birth injury (BPBI) are more likely to develop shoulder contracture and undergo surgical treatment. A retrospective review was conducted on children under 2 years old with BPBI who presented to a single children's hospital. The results showed that patients with EFC had reduced shoulder range of motion and higher odds of shoulder contracture and surgical treatment. Prompt referral to a BPBI specialty clinic is recommended for evaluation and potential surgery.
JOURNAL OF PEDIATRICS
(2024)
