Review
Oncology
Edward Young, Louisa Edwards, Rajvinder Singh
Summary: Artificial intelligence (AI) systems have become increasingly available in the field of endoscopy, particularly in colonoscopy. This comprehensive review focuses on the application of AI in detecting and characterizing colorectal polyps, with the goal of improving the efficacy of colorectal cancer screening and prevention. AI-driven algorithms show potential in addressing the challenge of overlooked polyps and empowering gastroenterologists to accurately characterize polyps without extensive training in advanced mucosal imaging. By integrating AI technologies into routine colonoscopy, the detection and characterization of polyps can be advanced, potentially leading to more effective colorectal cancer screening and prevention.
Article
Health Care Sciences & Services
Ka Luen Thomas Lui, Sze Hang Kevin Liu, Kathy Leung, Joseph T. Wu, Ann G. Zauber, Wai Keung Leung
Summary: The widespread adoption of computer-aided detection (CADe) in detecting colorectal polyps would result in shorter surveillance intervals for patients, particularly according to the US Multi-Society Task Force on Colorectal Cancer (USMSTF) guideline. Based on simulation, CADe application would lead to approximately 19.1% and 1.9% of patients requiring shorter surveillance intervals, as recommended by the USMSTF and European Society of Gastrointestinal Endoscopy (ESGE) guidelines, respectively. Specifically, all or 2.7% of patients initially scheduled for 3-5 years of surveillance would have their intervals shortened to 3 years, according to the USMSTF guideline.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Sergei Vosko, Neal Shahidi, Mayenaaz Sidhu, W. Arnout van Hattem, Iddo Bar-Yishay, Scott Schoeman, David J. Tate, Luke F. Hourigan, Rajvinder Singh, Alan Moss, Karen Byth, Eric Y. T. Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: This study found significant differences in optical evaluation performance between flat and nodular large nonpedunculated colorectal polyps. Flat lesions can be presumed benign and managed accordingly, while nodular lesions are more likely to be missed for submucosal invasive cancer.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Endocrinology & Metabolism
Leandro Kasuki, Bernardo Maia, Monica R. Gadelha
Summary: Acromegaly, caused by excessive secretion of GH and IGF-I, is associated with an increased risk of colorectal cancer (CRC), although the exact mechanism is not fully understood. GH and IGF-I may influence the tumor microenvironment in the colon through promoting angiogenesis, cell proliferation, mutation risk, and inhibiting tumor-suppressor genes and apoptosis. However, there is controversy regarding the incidence and mortality of CRC in acromegaly. Nonetheless, guidelines recommend colonoscopic screening and surveillance for acromegaly patients, although the best timing for this remains uncertain.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Myeongseok Koh, Min-Chan Kim, Jin Seok Jang
Summary: The prevalence of colorectal neoplasm and risk factors were compared between patients with gastric neoplasms and healthy individuals. The results showed that patients with gastric neoplasms had a higher prevalence of larger colon polyps and advanced colon adenomas. The presence of gastric neoplasms was identified as an important risk factor for advanced colon polyps.
Article
Gastroenterology & Hepatology
Mayenaaz Sidhu, Neal Shahidi, Sunil Gupta, Lobke Desomer, Sergei Vosko, W. Arnout van Hattem, Luke F. Hourigan, Eric Y. T. Lee, Alan Moss, Spiro Raftopoulos, Steven J. Heitman, Stephen J. Williams, Simon Zanati, David J. Tate, Nicholas Burgess, Michael J. Bourke
Summary: Thermal ablation of the defect margin after endoscopic mucosal resection (EMR-T) has been shown to significantly reduce residual or recurrent adenoma (RRA) at first surveillance colonoscopy. In an international multi-center prospective trial, EMR-T was found to be a simple, inexpensive, and highly effective auxiliary technique for managing large nonpedunculated colorectal polyps.
Article
Medicine, General & Internal
Alexandra F. Dalton, Carol E. Golin, Carolyn Morris, Christine E. Kistler, Rowena J. Dolor, Kaitlyn B. Bertin, Krithika Suresh, Swati G. Patel, Carmen L. Lewis
Summary: This secondary analysis aimed to investigate the impact of a targeted patient decision aid on the screening preferences of older adults for colorectal cancer (CRC) screening. The results of the study showed no significant differences in patient preferences between the intervention and control groups in different health states.
Article
Medicine, General & Internal
Mesay H. Asfaw, Sneha Adidam, Farshad Aduli, Angesom Kibreab, Joseph Asemota
Summary: Colonic mucosal prolapse syndrome is a rare condition that resembles neoplastic lesions and was incidentally found during colorectal cancer screening in a 65-year-old man. The patient was asymptomatic and had normal physical exam and laboratory test results. Colonoscopy revealed the presence of tubular adenomas and pedunculated polyps suspicious of neoplasms, along with small internal hemorrhoids. Histology confirmed the diagnosis of mucosal prolapse syndrome in the larger polyps, while the smaller polyps were consistent with tubular adenomas. Management involves removing associated polyps and conducting surveillance colonoscopy for monitoring recurrence and early signs of colorectal cancer.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Gastroenterology & Hepatology
Ahmir Ahmad, Ana Wilson, Adam Haycock, Adam Humphries, Kevin Monahan, Noriko Suzuki, Siwan Thomas-Gibson, Margaret Vance, Paul Bassett, Kowshika Thiruvilangam, Angad Dhillon, Brian P. Saunders
Summary: This study aimed to evaluate the effectiveness of CADe in colonoscopy. The results showed that CADe can improve PDR but did not have a significant improvement in ADR in a BCSP setting. CADe had limited benefits in procedures performed by experienced colonoscopists.
Article
Medicine, General & Internal
Toshihiro Nishizawa, Osamu Toyoshima, Shuntaro Yoshida, Chie Uekura, Ken Kurokawa, Munkhbayar Munkhjargal, Miho Obata, Tomoharu Yamada, Mitsuhiro Fujishiro, Hirotoshi Ebinuma, Hidekazu Suzuki
Summary: This study investigated the effectiveness of a novel image-enhancing endoscopic technique called texture and color enhancement imaging (TXI) in the imaging of serrated colorectal polyps. The results showed that TXI outperformed white light imaging (WLI) and narrow-band imaging (NBI) in terms of visibility for serrated polyps, particularly for sessile serrated lesions (SSLs).
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Miguel Pantaleon Sanchez, Antonio-Z Gimeno Garcia, Belen Bernad Cabredo, Ana Garcia-Rodriguez, Santiago Frago, Oscar Nogales, Pilar Diez Redondo, Ignasi Puig, Cristina Romero Mascarell, Ivan Romero Sanchez-Miguel, Noemi Caballero, Ines Ibanez, Domingo Hernandez Negrin, Gema Bujedo Sadornill, Alicia Perez Oltra, Rocio Perez Berbegal, Gemma Casals, Agustin Seoane Urgorri, Faust Riu Pons, Jaume Amoros, Marco Antonio Alvarez-Gonzalez
Summary: Repeat colonoscopy with adequate bowel preparation is recommended to avoid missing clinically relevant lesions in patients with inadequate bowel preparation. A significant proportion of advanced adenomas are discovered on repeat colonoscopy in patients with inadequate bowel preparation.
DIGESTIVE ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Osamu Toyoshima, Toshihiro Nishizawa, Shuntaro Yoshida, Hidenobu Watanabe, Nariaki Odawara, Kosuke Sakitani, Toru Arano, Hirotoshi Takiyama, Hideyuki Kobayashi, Hirofumi Kogure, Mitsuhiro Fujishiro
Summary: This study investigated the diagnostic yields of brown slits for adenomas. The results showed that brown slits had high sensitivity, specificity, and accuracy for adenoma diagnosis, making it an effective method for diagnosing colorectal adenomas.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Biochemical Research Methods
Cristoforo Simonetto, Ulrich Mansmann, Jan Christian Kaiser
Summary: The shape of colorectal adenoma affects its development and cancer risk. As the size increases and the shape becomes flat, the probability of adenoma transitioning to cancer increases. The shape of adenoma should be given closer consideration in screening strategies and as a risk factor for cancer transition.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Shun Kato, Shin-ei Kudo, Yosuke Minegishi, Yuki Miyata, Yasuharu Maeda, Takanori Kuroki, Yuki Takashina, Kenichi Mochizuki, Eri Tamura, Masahiro Abe, Yuta Sato, Tatsuya Sakurai, Yuta Kouyama, Kenta Tanaka, Yushi Ogawa, Hiroki Nakamura, Katsuro Ichimasa, Noriyuki Ogata, Tomokazu Hisayuki, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Toshiyuki Baba, Fumio Ishida, Tetsuo Nemoto, Masashi Misawa, Collaborators
Summary: This study evaluated the additional diagnostic value of computer-aided characterization in colonoscopy practice. It found that this technique improves the sensitivity and negative predictive value for colorectal polyps and enhances the high-confidence diagnosis rate.
DIGESTIVE ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Soham Rege, Elliot Coburn, Douglas J. Robertson, Audrey H. Calderwood
Summary: Only 35% of adults aged 75 and older are recommended to stop surveillance colonoscopy. The presence of polyps was strongly associated with fewer recommendations to stop. The variation in endoscopist recommendations highlights an opportunity to better standardize recommendations following colonoscopy in older adults.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Yoshihiro Kishida, Kinichi Hotta, Kenichiro Imai, Sayo Ito, Yohei Yabuuchi, Masao Yoshida, Noboru Kawata, Naomi Kakushima, Kohei Takizawa, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi, Hiroyuki Ono
Summary: This study showed that removing the suction valve button during polyp retrieval can effectively reduce fragmentation rates and histological unclear margins.
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Kazuya Hosotani, Kenichiro Imai, Kinichi Hotta, Sayo Ito, Yoshihiro Kishida, Yohei Yabuuchi, Masao Yoshida, Noboru Kawata, Naomi Kakushima, Kohei Takizawa, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi, Hiroyuki Ono
Summary: This study evaluated the diagnostic yield of combining M-NBI and M-CE for T1 colorectal cancer, showing that stratification by JNET classification using M-NBI and additional M-CE can improve the diagnosis of JNET Type 2B lesions.
DIGESTIVE ENDOSCOPY
(2021)
Letter
Gastroenterology & Hepatology
Kenichiro Imai, Kinichi Hotta, Hiroyuki Ono
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Sayo Ito, Kinichi Hotta, Kenichiro Imai, Yoshihiro Kishida, Kohei Takizawa, Naomi Kakushima, Noboru Kawata, Masao Yoshida, Yohei Yabuuchi, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi, Akio Shiomi, Hiroyuki Ono
Summary: Preoperative colonoscopy for stenotic colorectal cancers is often incomplete. This study found that an ultrathin colonoscope could be used to inspect the whole colon proximal to the stenosis, detecting synchronous neoplasias that could potentially change the treatment strategy before surgery. (UMIN000028505)
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Yutaka Saito, Shiro Oka, Takuji Kawamura, Ryo Shimoda, Masau Sekiguchi, Naoto Tamai, Kinichi Hotta, Takahisa Matsuda, Masashi Misawa, Shinji Tanaka, Yosuke Iriguchi, Ryoichi Nozaki, Hironori Yamamoto, Masahiro Yoshida, Kazuma Fujimoto, Haruhiro Inoue
Summary: The guidelines for colonoscopy screening and surveillance were developed by the Japan Gastroenterological Endoscopy Society based on scientific methods and expert consensus. Limited high-level evidence in this field required a focus on expert opinions. The guidelines consist of 20 clinical questions and eight background knowledge topics as the current guiding principles.
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Yoshihiro Kishida, Kohei Takizawa, Naomi Kakushima, Noboru Kawata, Masao Yoshida, Yohei Yabuuchi, Yoichi Yamamoto, Sayo Ito, Kenichiro Imai, Kinichi Hotta, Hirotoshi Ishiwatari, Hiroyuki Matsubayashi, Etsuro Bando, Masanori Terashima, Hiroyuki Ono
Summary: In elderly patients with relative ER-indication EGC, ESD may have comparable long-term efficacy to surgery, and treatment selection had a minor contribution to overall survival (OS). For patients with poor preoperative prognostic factors, diagnostic ESD may be performed first, followed by additional surgery based on pathological results.
DIGESTIVE ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Nozomu Kobayashi, Yoji Takeuchi, Ken Ohata, Masahiro Igarashi, Masayoshi Yamada, Shinya Kodashima, Kinichi Hotta, Keita Harada, Hiroaki Ikematsu, Toshio Uraoka, Naoto Sakamoto, Hisashi Doyama, Takashi Abe, Atsushi Katagiri, Shinichiro Hori, Tomoki Michida, Takehito Yamaguchi, Masakatsu Fukuzawa, Shinsuke Kiriyama, Kazutoshi Fukase, Yoshitaka Murakami, Hideki Ishikawa, Yutaka Saito
Summary: This multicenter prospective trial in Japan aimed to quantify the rates of en bloc and curative resections, as well as complications, in endoscopic submucosal dissection (ESD) for colorectal lesions. The study revealed higher curability, shorter procedure time, and lower risk of complications compared to previous reports.
DIGESTIVE ENDOSCOPY
(2022)
Editorial Material
Gastroenterology & Hepatology
Kazunori Takada, Kinichi Hotta, Kenichiro Imai
DIGESTIVE ENDOSCOPY
(2022)
Editorial Material
Gastroenterology & Hepatology
Kinichi Hotta
DIGESTIVE ENDOSCOPY
(2022)
Editorial Material
Gastroenterology & Hepatology
Kazunori Takada, Kinichi Hotta, Kenichiro Imai
DIGESTIVE ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Kinichi Hotta, Shozo Osera, Kei Shinoki, Kenichiro Imai, Sayo Ito, Yuichiro Yamaguchi, Yoshihiro Kishida, Kazunori Takada, Hiroyuki Ono
Summary: The feasibility of endoscopic submucosal dissection (ESD) for ileocecal valve lesions (ICVL) and peri-appendiceal orifice lesions (PAOL) was evaluated. The results showed high rates of curative resection and colon preservation for ICVL and PAOL.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Gastroenterology & Hepatology
Masau Sekiguchi, Takahisa Matsuda, Kinichi Hotta, Yutaka Saito
Summary: An effective and safe post-polypectomy surveillance program should consider risk stratification based on baseline colonoscopy results. Major international guidelines have recommended and updated risk-stratified surveillance programs, with more individuals being classified as low-risk for less frequent or no surveillance. The new colonoscopy screening and surveillance guidelines in Japan also incorporate risk-stratified post-polypectomy surveillance.
CLINICAL ENDOSCOPY
(2022)
Editorial Material
Gastroenterology & Hepatology
Kohei Shigeta, Kenichiro Imai, Kinichi Hotta
DIGESTIVE ENDOSCOPY
(2023)
Editorial Material
Gastroenterology & Hepatology
Taishi Okumura, Kenichiro Imai, Kinichi Hotta
DIGESTIVE ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Daiki Kawaguchi, Kazunori Takada, Kinichi Hotta
DIGESTIVE ENDOSCOPY
(2023)
