The Molecular Pathogenesis of Colorectal Cancer and Its Potential Application to Colorectal Cancer Screening
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Molecular Pathogenesis of Colorectal Cancer and Its Potential Application to Colorectal Cancer Screening
Authors
Keywords
Colon cancer, Biomarkers, Microsatellite instability, MSI, Chromosome instability, Epigenomic instability
Journal
DIGESTIVE DISEASES AND SCIENCES
Volume 60, Issue 3, Pages 762-772
Publisher
Springer Nature
Online
2014-12-09
DOI
10.1007/s10620-014-3444-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Progress and Opportunities in Molecular Pathological Epidemiology of Colorectal Premalignant Lesions
- (2014) Paul Lochhead et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Critical Appraisal of the Diagnosis of the Sessile Serrated Adenoma
- (2014) Mark Bettington et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- B-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P
- (2014) A Inoue et al. BRITISH JOURNAL OF CANCER
- Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression From Adenoma to Colorectal Cancer
- (2014) Yanxin Luo et al. GASTROENTEROLOGY
- Aging and epigenetic drift: a vicious cycle
- (2014) Jean-Pierre Issa JOURNAL OF CLINICAL INVESTIGATION
- Modulation of Age- and Cancer-Associated DNA Methylation Change in the Healthy Colon by Aspirin and Lifestyle
- (2014) Faiza Noreen et al. JNCI-Journal of the National Cancer Institute
- Multitarget Stool DNA Testing for Colorectal-Cancer Screening
- (2014) Thomas F. Imperiale et al. NEW ENGLAND JOURNAL OF MEDICINE
- Slug is temporally regulated by cyclin E in cell cycle and controls genome stability
- (2014) W-L Wang et al. ONCOGENE
- RNA Sequencing of Sessile Serrated Colon Polyps Identifies Differentially Expressed Genes and Immunohistochemical Markers
- (2014) Don A. Delker et al. PLoS One
- Synchronous colorectal cancer: Clinical, pathological and molecular implications
- (2014) Alfred King-Yin Lam WORLD JOURNAL OF GASTROENTEROLOGY
- Field cancerization in the colon: a role for aberrant DNA methylation?
- (2014) Y. Luo et al. Gastroenterology Report
- Serum miR-200c Is a Novel Prognostic and Metastasis-Predictive Biomarker in Patients With Colorectal Cancer
- (2013) Yuji Toiyama et al. ANNALS OF SURGERY
- Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas
- (2013) A. N. Burnett-Hartman et al. CANCER RESEARCH
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Metachronous Serrated Neoplasia Is Uncommon After Right Colectomy in Patients with Methylator Colon Cancers With a High Degree of Microsatellite Instability
- (2013) Craig A. Messick et al. DISEASES OF THE COLON & RECTUM
- Colorectal Carcinomas With CpG Island Methylator Phenotype 1 Frequently Contain Mutations in Chromatin Regulators
- (2013) Tomomitsu Tahara et al. GASTROENTEROLOGY
- Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis
- (2013) Keun Hur et al. GUT
- Similarities of Molecular Genetic Changes in Synchronous and Metachronous Colorectal Cancers Are Limited and Related to the Cancers’ Proximities to Each Other
- (2013) Peter Zauber et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Extensive Telomere Erosion in the Initiation of Colorectal Adenomas and Its Association With Chromosomal Instability
- (2013) Laureline Roger et al. JNCI-Journal of the National Cancer Institute
- Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
- (2013) Austin M Dulak et al. NATURE GENETICS
- Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa
- (2012) Henri S. Tapp et al. AGING CELL
- Molecular pathogenesis of IDH mutations in gliomas
- (2012) Koichi Ichimura Brain Tumor Pathology
- Centrosome amplification in tumorigenesis
- (2012) Simon J. Anderhub et al. CANCER LETTERS
- The serrated pathway to colorectal carcinoma: current concepts and challenges
- (2012) Mark Bettington et al. HISTOPATHOLOGY
- Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma
- (2012) Pablo Conesa-Zamora et al. INTERNATIONAL JOURNAL OF CANCER
- Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2
- (2012) Claudia A. Doege et al. NATURE
- DNA demethylation in normal colon tissue predicts predisposition to multiple cancers
- (2012) H Kamiyama et al. ONCOGENE
- A study of genomic instability in early preneoplastic colonic lesions
- (2012) A D Beggs et al. ONCOGENE
- Molecular Features of Colorectal Hyperplastic Polyps and Sessile Serrated Adenoma/Polyps From Korea
- (2011) Kyoung-Mee Kim et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Histologic characteristics of non–microsatellite-instable colon adenomas correlate with distinct molecular patterns
- (2011) Agnès Neuville et al. HUMAN PATHOLOGY
- Candidate driver genes in microsatellite-unstable colorectal cancer
- (2011) Pia Alhopuro et al. INTERNATIONAL JOURNAL OF CANCER
- Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas
- (2010) Bogdan C. Paun et al. CANCER
- Association between Folate Levels and CpG Island Hypermethylation in Normal Colorectal Mucosa
- (2010) K. Wallace et al. Cancer Prevention Research
- Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner
- (2010) O. Gilad et al. CANCER RESEARCH
- Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa
- (2010) Nigel J. Belshaw et al. CARCINOGENESIS
- The Chromosomal Instability Pathway in Colon Cancer
- (2010) Maria S. Pino et al. GASTROENTEROLOGY
- Role of the Serrated Pathway in Colorectal Cancer Pathogenesis
- (2010) Barbara Leggett et al. GASTROENTEROLOGY
- Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability
- (2010) Cristina Albuquerque et al. GENES CHROMOSOMES & CANCER
- Cigarette Smoking and Colorectal Cancer Risk by Molecularly Defined Subtypes
- (2010) David Limsui et al. JNCI-Journal of the National Cancer Institute
- Serrated Polyps and Colorectal Cancer: New Pathway to Malignancy
- (2009) Amy E. Noffsinger Annual Review of Pathology-Mechanisms of Disease
- Global DNA Hypomethylation (LINE-1) in the Normal Colon and Lifestyle Characteristics and Dietary and Genetic Factors
- (2009) J. C. Figueiredo et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype
- (2009) Hiromu Suzuki et al. CARCINOGENESIS
- Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning
- (2009) Rebecca A. Hinshelwood et al. HUMAN MOLECULAR GENETICS
- Methylation status of normal background mucosa is correlated with occurrence and development of neoplasia in the distal colon
- (2009) Sakiko Hiraoka et al. HUMAN PATHOLOGY
- A Network Model of a Cooperative Genetic Landscape in Brain Tumors
- (2009) Markus Bredel et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor–Targeted Therapy in Metastatic Colorectal Cancer
- (2009) Salvatore Siena et al. JNCI-Journal of the National Cancer Institute
- DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer
- (2009) D L Worthley et al. ONCOGENE
- Analysis of the Association between CIMP and BRAFV600E in Colorectal Cancer by DNA Methylation Profiling
- (2009) Toshinori Hinoue et al. PLoS One
- A Simplified, Noninvasive Stool DNA Test for Colorectal Cancer Detection
- (2008) Steven Itzkowitz et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa
- (2008) N J Belshaw et al. BRITISH JOURNAL OF CANCER
- Hypermethylator Phenotype in Sporadic Colon Cancer: Study on a Population-Based Series of 582 Cases
- (2008) L. Barault et al. CANCER RESEARCH
- Genomic and Epigenetic Instability in Colorectal Cancer Pathogenesis
- (2008) William M. Grady et al. GASTROENTEROLOGY
- Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis
- (2008) A Walther et al. GUT
- LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
- (2008) Shuji Ogino et al. INTERNATIONAL JOURNAL OF CANCER
- Predicting clinical outcome of 5-fluorouracil-based chemotherapy for colon cancer patients: is the CpG island methylator phenotype the 5-fluorouracilresponsive subgroup?
- (2008) Barry Iacopetta et al. International Journal of Clinical Oncology
- Assessing the Measure of a New Drug: Is Survival the Only Thing That Matters?
- (2008) Daniel J. Sargent et al. JOURNAL OF CLINICAL ONCOLOGY
- A stochastic carcinogenesis model incorporating multiple types of genomic instability fitted to colon cancer data
- (2008) Mark P. Little et al. JOURNAL OF THEORETICAL BIOLOGY
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer
- (2008) W M Grady et al. ONCOGENE
- Comprehensive Biostatistical Analysis of CpG Island Methylator Phenotype in Colorectal Cancer Using a Large Population-Based Sample
- (2008) Katsuhiko Nosho et al. PLoS One
- Defining ‘chromosomal instability’
- (2008) Jochen B. Geigl et al. TRENDS IN GENETICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now