Article
Gastroenterology & Hepatology
Amy L. Lightner, Sarah Vogler, John McMichael, Xue Jia, Miguel Regueiro, Taha Qazi, Scott R. Steele
Summary: While UC patients were more likely to have neoplasia detected during colonoscopy, the rates of progression from LGD and HGD to adenocarcinoma were equivalent in UC and CD, suggesting consistent endoscopic surveillance strategies for all IBD patients.
JOURNAL OF CROHNS & COLITIS
(2021)
Article
Gastroenterology & Hepatology
Samuel Tanner, Jeffry Katz, Fabio Cominelli, Miguel Regueiro, Gregory Cooper, Emad Mansoor
Summary: This article examines the prevalence of inflammatory bowel disease in patients with gastritis, duodenitis, and peptic ulcer disease, taking into consideration the presence of Helicobacter pylori infection. It is found that inflammatory bowel disease is less common in patients with H. pylori, and there is no increased risk of developing IBD after undergoing H. pylori eradication therapy.
INFLAMMATORY BOWEL DISEASES
(2023)
Article
Multidisciplinary Sciences
Iyad Ali, Qusay Abdo, Shayma'a M. Al-Hihi, Ansam Shawabkeh
Summary: This study investigated the association between Helicobacter pylori (H. pylori) colonization and ulcerative colitis (UC) in Palestine. The results showed a significantly lower H. pylori infection rate in patients with UC compared to the control group, suggesting a potential protective role of H. pylori against UC occurrence.
Article
Gastroenterology & Hepatology
Julien Kirchgesner, Rishi J. Desai, Maria C. Schneeweiss, Laurent Beaugerie, Sebastian Schneeweiss, Seoyoung C. Kim
Summary: Combination therapy with vedolizumab and thiopurines is associated with a lower risk of treatment failure compared to vedolizumab monotherapy in patients with CD, but the effect is less pronounced in UC.
Review
Medicine, General & Internal
Guiping Kong, Zhifeng Liu, Yan Lu, Mei Li, Hongmei Guo
Summary: This systematic review and meta-analysis found no correlation between H. pylori infection and the occurrence of IBD in children.
Review
Immunology
Reza Yarani, Ali Shojaeian, Oana Palasca, Nadezhda T. Doncheva, Lars Juhl Jensen, Jan Gorodkin, Flemming Pociot
Summary: This review discusses the differential regulation of miRNAs in inflammatory bowel disease (IBD) and their potential diagnostic and therapeutic applications. Through literature curation and computational analysis, a consensus set of differentially expressed miRNAs in mucosal tissues was obtained. The role of these miRNAs and their potential targets in IBD are highlighted.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Gastroenterology & Hepatology
Tatsuki Noguchi, Soichiro Ishihara, Motoi Uchino, Hiroki Ikeuchi, Koji Okabayashi, Kitaro Futami, Shinji Tanaka, Hiroki Ohge, Hisashi Nagahara, Kazuhiro Watanabe, Michio Itabashi, Kinya Okamoto, Yoshiki Okita, Tsunekazu Mizushima, Yusuke Mizuuchi, Kazutaka Yamada, Yoshifumi Shimada, Yu Sato, Hideaki Kimura, Kenichi Takahashi, Koya Hida, Yusuke Kinugasa, Junji Okuda, Koji Daito, Fumikazu Koyama, Hideki Ueno, Takayuki Yamamoto, Tsunekazu Hanai, Atsuo Maemoto, Koji Oba, Yoichi Ajioka, Kenichi Sugihara
Summary: Patients with longstanding inflammatory bowel disease, such as ulcerative colitis and Crohn's disease, are at high risk of developing intestinal cancers. This study found significant differences between intestinal cancers associated with ulcerative colitis and Crohn's disease. Crohn's disease-associated cancers were diagnosed at more advanced stages, detected less frequently by surveillance, and had a poorer prognosis compared to those associated with ulcerative colitis.
JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Biochemical Research Methods
Florent Clerc, Karli R. Reiding, Noortje de Haan, Carolien A. M. Koeleman, Agnes L. Hipgrave Ederveen, Natalia Manetti, Viktoria Dotz, Vito Annese, Manfred Wuhrer
Summary: This study investigates the associations of immunoglobulin A1 and A2 glycosylation with inflammatory bowel diseases (IBD). Differences in IgA O- and N-glycosylation between patient groups were found to be associated with the diseases, and a statistical model was constructed to predict the disease group of the patients. These findings contribute to the development of noninvasive biomarkers for IBD and improvement in patient care.
JOURNAL OF PROTEOME RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Ji Yeong Yang, Jong-Bae Kim, Pyeongjae Lee, Sa-Hyun Kim
Summary: Evodiamine inhibits the growth of H. pylori by downregulating gene expressions related to replication and transcription machineries of the bacteria. Moreover, evodiamine also suppresses urease expression, leading to reduced translocation of CagA and VacA proteins into AGS cells. Additionally, evodiamine inhibits the activation of signaling proteins induced by H. pylori infection, contributing to reduction of IL-8 production in AGS cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Public, Environmental & Occupational Health
Kasper Monsted Pedersen, Yunus Colak, Signe Vedel-Krogh, Camilla Jannie Kobylecki, Stig Egil Bojesen, Borge Gronne Nordestgaard
Summary: The study found that smoking was associated with an increased risk of ulcerative colitis, while offering potential protection against Crohn's disease. However, genetic evidence did not support a causal relationship between smoking intensity and the development of these inflammatory bowel diseases.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Mengfan Luo, Qiaoyue Yuan, Mingzhen Liu, Xingye Song, Yingjie Xu, Tao Zhang, Xiaoqun Zeng, Zhen Wu, Daodong Pan, Yuxing Guo
Summary: This study aimed to develop a novel astaxanthin nanoparticle using gum arabic (GA) and whey protein powder enriched with milk fat globule membranes (MFGM-WPI) as carriers and investigated its effect and alleviation mechanism on colitis in mice. Results showed that MFGM-GA-astaxanthin effectively improved bioaccessibility of astaxanthin, reduced oxidative stress, alleviated colitis symptoms, repaired intestinal barrier function, and restored abnormalities of gut flora. This study provides a promising therapeutic approach for colon diseases using astaxanthin nanoparticles.
Article
Gastroenterology & Hepatology
Antoine Meyer, Catherine Dong, Corinne Casagrande, Simon S. M. Chan, Inge Huybrechts, Genevieve Nicolas, Fernanda Rauber, Renata Bertazzi Levy, Christopher Millett, Bas Oldenburg, Elisabete Weiderpass, Alicia K. Heath, Tammy Y. N. Tong, Anne Tjonneland, Cecilie Kyro, Rudolf Kaaks, Verena A. Katzke, Manuela M. Bergman, Domenico Palli, Giovanna Masala, Rosario Tumino, Carlotta Sacerdote, Sandra M. Colorado-Yohar, Maria-Jose Sanchez, Olof Grip, Stefan Lindgren, Robert Luben, Marc J. Gunter, Yahya Mahamat-Saleh, Marie-Christine Boutron-Ruault, Franck Carbonnel
Summary: The study found that consuming unprocessed/minimally processed foods is associated with a lower risk of Crohn's disease, but not with the risk of ulcerative colitis.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Julian Hercun, Justin Cote-Daigneault, Raymond G. Lahaie, Carole Richard, Ramses Wassef, Pierre Poitras
Summary: The study found that Crohn's disease can develop postoperatively with an increasing cumulative incidence over time. Preoperative predictive factors are limited and should not determine candidacy for surgery. Most patients have favorable outcomes with medical therapy, while 16% of Crohn's disease patients require pouch removal.
DISEASES OF THE COLON & RECTUM
(2021)
Article
Gastroenterology & Hepatology
Anika Varma, Jennifer Weinstein, Jamison Seabury, Spencer Rosero, Ellen Wagner, Christine Zizzi, Elizabeth Luebbe, Nuran Dilek, Michael McDermott, John Heatwole, Lawrence Saubermann, Larissa Temple, Scott Rogoff, Chad Heatwole
Summary: This study aimed to identify the most prevalent and impactful symptoms in patients with Crohn's disease (CD) and to determine the modifying factors associated with a higher disease burden in CD.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Scott Friedberg, David Choi, Thomas Hunold, Natalie K. Choi, Nicole M. Garcia, Emma A. Picker, Nathaniel A. Cohen, Russell D. Cohen, Sushila R. Dalal, Joel Pekow, Atsushi Sakuraba, Noa Krugliak Cleveland, David T. Rubin
Summary: In this study, the authors reported a large real-world experience with the use of upadacitinib in patients with ulcerative colitis and Crohn's disease. They found that upadacitinib was rapidly effective and safe, even in patients who had prior exposure to tofacitinib.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Meeting Abstract
Gastroenterology & Hepatology
Sara Tadbiri, Jean-charles Grimaud, Laurent Peyrin-Biroulet, Jerome Filippi, Benjamin Pariente, Xavier Roblin, Anthony Buisson, Carmen Stefanescu, Caroline Trang, Romain Altwegg, Philippe R. Marteau, Thibaut Vaysse, Anne Bourrier, David Laharie, Matthieu Allez, Yoram Bouhnik, Aurelien Amiot
Article
Gastroenterology & Hepatology
Driffa Moussata, Matthieu Allez, Dominique Cazals-Hatem, Xavier Treton, David Laharie, Jean-Marie Reimund, Philippe Bertheau, Arnaud Bourreille, Anne Lavergne-Slove, Hedia Brixi, Julien Branche, Jean-Marc Gornet, Carmen Stefanescu, Jacques Moreau, Philippe Marteau, Anne-Laure Pelletier, Franck Carbonnel, Philippe Seksik, Marion Simon, Jean-Francois Flejou, Jean-Frederic Colombel, Anne-Laure Charlois, Xavier Roblin, Stephane Nancey, Yoram Bouhnik, Francoise Berger, Bernard Flourie
Article
Gastroenterology & Hepatology
Romain Leenhardt, Pauline Vasseur, Cynthia Li, Jean Christophe Saurin, Gabriel Rahmi, Franck Cholet, Aymeric Becq, Philippe Marteau, Aymeric Histace, Xavier Dray
GASTROINTESTINAL ENDOSCOPY
(2019)
Article
Gastroenterology & Hepatology
Charlotte Gagniere, Anne Bourrier, Philippe Seksik, Jean-Marc Gornet, Olivier DeWit, Stephane Nancey, Romain Altwegg, Vered Abitbol, David Laharie, Catherine Reenaers, Anthony Buisson, Benjamin Pariente, Stephanie Viennot, Lucine Vuitton, Carmen Stefanescu, Philippe Marteau, Guillaume Bouguen, Jacques Cosnes, Aurelien Amiot
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2018)
Article
Infectious Diseases
Christoph Hoegenauer, Yashwant Mahida, Andreas Stallmach, Philippe Marteau, Grazyna Rydzewska, Vladimir Ivashkin, Panagiotis Gargalianos-Kakolyris, Ingrid Michon, Nicholas Adomakoh, Areti Georgopali, Reiner Tretter, Andreas Karas, Walter Reinisch
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2018)
Article
Multidisciplinary Sciences
Cecilia Landman, Jean-Pierre Grill, Jean-Maurice Mallet, Philippe Marteau, Lydie Humbert, Eric Le Balc'h, Marie-Anne Maubert, Kevin Perez, Wahiba Chaara, Loic Brot, Laurent Beaugerie, Harry Sokol, Sophie Thenet, Dominique Rainteau, Philippe Seksik, Elodie Quevrain
Article
Nutrition & Dietetics
Philippe Marteau, Boris Le Neve, Laurent Quinquis, Caroline Pichon, Peter J. Whorwell, Denis Guyonnet
Article
Gastroenterology & Hepatology
Matthieu Allez, Claire Auzolle, Marjolaine Ngollo, Hugo Bottois, Victor Chardiny, Ana Maria Corraliza, Azucena Salas, Kevin Perez, Carmen Stefanescu, Stephane Nancey, Anthony Buisson, Benjamin Pariente, Mathurin Fumery, Harry Sokol, Xavier Treton, Nicolas Barnich, Philippe Seksik, Lionel Le Bourhis, Pierre Cattan, Mircea Chirica, Nicolas Munoz-Bongrand, Helene Corte, Jean-Marc Gornet, Clotilde Baudry, Nelson Lourenco, Mariane Maillet, My-Linh Tran-Minh, Andree Nisard, Laurent Beaugerie, Anne Bourrier, Isabelle Nion-Larmurier, Cecilia Landman, Sylvie Rajca, Elodie Quevrain, Loic Brot, Najim Chafai, Jeremie Lefevre, Emmanuel Tiret, Magali Svreck, Nadia Hoyau-ldrissi, Jean Francois Flejou, Nathalie Guedj, Yves Panis, Leon Magiorri, Mariane Feron, Yoram Bouhnik, Olivier Corcos, Dominique Cazals-Hatem, Xavier Dray, Ulrika Chaput, Philippe Marteau, Gilles Bommelaer, Marion Goutte, Emilie Vazeille, Michael Rodrigues, Pierre Sauvanet, Pierre Desreumaux, Maria Nachury, Coralie Sommeville, Jean-Louis Dupas, Franck Brazier, Denis Chatelain, Christophe Attencourt, Charles Sabbagh, Martine Leconte, Gilles Boschetti, Bernard Flourie, Yves Francois, Eddy Cotte, Anne-Laure Charlois, Peggy Falgon, Driffa Moussata, Marion Chauvenet, Sarah Boyer, Xavier Hebuterne, Jerome Filippi, Paul Hofmann, Madeleine Bezeault, Carole Margalef, Patricia Detre
Article
Gastroenterology & Hepatology
Romain Leenhardt, Cynthia Li, Anastasios Koulaouzidis, Flaminia Cavallaro, Franck Cholet, Rami Eliakim, Ignacio Fernandez-Urien, Uri Kopylov, Mark McAlindon, Artur Nemeth, John N. Plevris, Gabriel Rahmi, Emanuele Rondonotti, Jean-Christophe Saurin, Gian Eugenio Tontini, Ervin Toth, Diana Yung, Philippe Marteau, Xavier Dray
ENDOSCOPY INTERNATIONAL OPEN
(2019)
Article
Gastroenterology & Hepatology
Aymeric Becq, Aymeric Histace, Marine Camus, Isabelle Nion-Larmurier, Einas Abou Ali, Olivia Pietri, Olivier Romain, Ulriikka Chaput, Cynthia Li, Philippe Marteau, Christian Florent, Xavier Dray
ENDOSCOPY INTERNATIONAL OPEN
(2018)
Article
Critical Care Medicine
Andrea Cortegiani, Fabiana Madotto, Cesare Gregoretti, Giacomo Bellani, John G. Laffey, Tai Pham, Frank Van Haren, Antonino Giarratano, Massimo Antonelli, Antonio Pesenti, Giacomo Grasselli
Article
Gastroenterology & Hepatology
Einas Abou Ali, Aymeric Histace, Marine Camus, Rafaele Gerometta, Aymeric Becq, Olivia Pietri, Isabelle Nion-Larmurier, Cynthia Li, Ulriikka Chaput, Philippe Marteau, Christian Florent, Xavier Dray
ENDOSCOPY INTERNATIONAL OPEN
(2018)
Article
Gastroenterology & Hepatology
Olivia Pietri, Gada Rezgui, Aymeric Histace, Marine Camus, Isabelle Nion-Larmurier, Cynthia Li, Aymeric Becq, Einas Abou Ali, Olivier Romain, Ulriikka Chaput, Philippe Marteau, Christian Florent, Xavier Dray
ENDOSCOPY INTERNATIONAL OPEN
(2018)
Article
Gastroenterology & Hepatology
S. Tadbiri, L. Peyrin-Biroulet, M. Serrero, J. Filippi, B. Pariente, X. Roblin, A. Buisson, C. Stefanescu, C. Trang-Poisson, R. Altwegg, P. Marteau, T. Vaysse, A. Bourrier, S. Nancey, D. Laharie, M. Allez, G. Savoye, C. Gilletta, C. Gagniere, L. Vuitton, S. Viennot, A. Aubourg, A. -L. Pelletier, G. Bouguen, V. Abitbol, M. Fumery, P. Claudepierre, Y. Bouhnik, A. Amiot
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2018)
Article
Gastroenterology & Hepatology
Claire Auzolle, Stephane Nancey, My-Linh Tran-Minh, Anthony Buisson, Benjamin Pariente, Carmen Stefanescu, Mathurin Fumery, Philippe Marteau, Xavier Treton, Nassim Hammoudi, Xavier Jouven, Philippe Seksik, Matthieu Allez
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2018)