Article
Microbiology
Valentina Fainardi, Chiara Sodini, Michela Deolmi, Andrea Ciuni, Kaltra Skenderaj, Maria Bice Stabile, Cosimo Neglia, Elena Mariotti Zani, Cinzia Spaggiari, Nicola Sverzellati, Susanna Esposito, Giovanna Pisi
Summary: This study demonstrates the significant clinical impact of ABPA and Af sensitization on lung function and structural damage in CF patients, leading to more exacerbations and lower BMI.
Article
Medicine, General & Internal
Ioana Mihaiela Ciuca, Liviu Laurentiu Pop, Mihaela Dediu, Emil Robert Stoicescu, Monica Steluta Marc, Aniko Maria Manea, Diana Luminita Manolescu
Summary: The aim of this study was to evaluate a newly designed lung ultrasound (LUS) score and compare it with the modified Bhalla CT score in patients with cystic fibrosis (CF). The results showed a strong correlation between the LUS score and CT score, with higher sensitivity in detecting atelectasis and consolidations. These findings suggest that the LUS score can be a useful tool for the diagnosis and monitoring of CF lung disease in children.
Article
Pediatrics
Massimiliano Giardina, David Barilla, Claudia Crimi, Amelia Arone, Filippo Benedetto, Cristina Lucanto, Rossella Natoli, Roberto Messina, Antonio David, Alberto Noto
Summary: The study suggests that ultrasound-guided positioning of LPCs is a safe alternative means of peripheral venous access in children with chronic diseases such as CF.
PEDIATRIC PULMONOLOGY
(2022)
Article
Food Science & Technology
Saeedeh Talebi, Andrew S. Day, Mahammad Safarian, Seyed Javad Sayedi, Mahmood Reza Jaafari, Zahra Abbasi, Hanieh Barghchi, Hamid Reza Kianifar
Summary: This prospective randomized clinical trial aimed to evaluate the effects of nano-curcumin as an anti-inflammatory agent and a CFTR modulator on clinical and inflammatory markers in children with CF. The results showed that nano-curcumin decreased the levels of high-sensitivity C-reactive protein and fecal calprotectin, and increased the level of interleukin-10. Moreover, it improved the overall quality of life and the subscale scores of the questionnaire.
FOOD SCIENCE & NUTRITION
(2023)
Review
Nutrition & Dietetics
Elena Mariotti Zani, Roberto Grandinetti, Daniela Cunico, Lisa Torelli, Valentina Fainardi, Giovanna Pisi, Susanna Esposito
Summary: Patients with cystic fibrosis (CF) are prone to malnutrition and growth failure due to malabsorption caused by chloride transport derangement. Optimal nutritional care and support are crucial for improving clinical outcomes and life expectancy. This report analyzes the nutrition support in CF patients of different ages, focusing on the relationship with growth, nutritional status, disease outcomes, and the use of CFTR modulators. Early nutrition support in CF should aim at achieving optimal nutritional status to support growth and development in children and maintain it in adulthood. This involves a high calorie, high-fat diet, pancreatic enzyme replacement therapy, and adequate supplementation of fat-soluble vitamins. Supplemental enteral feeding may be needed when oral intake is insufficient. CFTR modulators have positive effects on nutritional status, including weight gain, BMI improvement, pulmonary function, and reduction of exacerbations. Challenges remain in developing new drugs to transform CF into a treatable chronic disease with specialized multidisciplinary care.
Article
Pediatrics
Steven Levitte, Lori W. Lee, Jared Isaacson, Evan J. Zucker, Carlos Milla, Richard A. Barth, Zachary M. Sellers
Summary: The study introduced SWE technology to aid in detecting liver fibrosis in children with CF, finding that 6-MHz point SWE correlated with MR elastography, and SWE at 1.84 m/s could effectively differentiate the severity of liver stiffness, providing a tool for predicting liver fibrosis.
PEDIATRIC RADIOLOGY
(2021)
Article
Pediatrics
Raphael Enaud, Eric Frison, Sophie Missonnier, Aude Fischer, Victor de Ledinghen, Paul Perez, Stephanie Bui, Michael Fayon, Jean-Francois Chateil, Thierry Lamireau
Summary: This study evaluated the repeatability and reproducibility of TE and pSWE VTQ in children with CF, finding both techniques to be reliable for assessing liver fibrosis. The high ICC values obtained suggest that TE and pSWE VTQ can be used effectively in the follow-up of CF patients, depending on their availability in CF centers.
PEDIATRIC RESEARCH
(2022)
Review
Pediatrics
Riccardo Schiaffini, Valentina Pampanini
Summary: The purpose of this review is to provide an update on the diagnosis and therapy of glucose metabolism alterations in cystic fibrosis, including cystic fibrosis-related diabetes (CFRD) and glucose intolerance. Recent findings confirm the use of Oral Glucose Tolerance Test as the diagnostic gold standard, while continuous glucose monitoring (CGM) systems have shown effectiveness in managing and guiding CFRD therapy. Tailored insulin therapy, nutritional intervention, and oral hypoglycemic treatment are recommended for children and adolescents with CFRD.
CURRENT OPINION IN PEDIATRICS
(2023)
Article
Physiology
Fanny Gabrysz-Forget, Anne-Catherine Maynard-Paquette, Aileen Kharat, Francois Tremblay, Maite Silviet-Carricart, Annick Lavoie, Martin Girard, Bruno-Pierre Dube
Summary: In patients with cystic fibrosis, diaphragm ultrasound can serve as a reliable and non-invasive marker of disease severity, providing information on respiratory and extra-pulmonary manifestations of the disease and clinical outcomes. Further research is needed to explore its potential as a longitudinal marker of disease progression, response to interventions, or therapeutic target.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Dermatology
A. Alexopoulos, G. Chouliaras, T. Kakourou, M. Dakoutrou, A. Petrocheilou, L. Nasi, I. Thanopoulou, S. Siahanidou, C. Kanaka-Gantenbein, L. Kontara, A. Michos, I. Loukou
Summary: This study investigated the issue of palmar wrinkling in cystic fibrosis (CF) patients and explored the pathomechanism of this phenomenon. The results showed significant associations between palmar wrinkling and characteristics such as history of allergies, history of hyperhidrosis, and sweat chloride levels. Therefore, observing the appearance of palmar wrinkling could be used as an initial screening tool to identify individuals who may have CF.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Review
Endocrinology & Metabolism
Kelly A. Mason, Alan D. Rogol
Summary: Since the first description of cystic fibrosis (CF) in 1938, there have been significant discoveries and innovations in the field that have had a profound impact on the quality of life for patients. Interventions such as improving nutritional status, pulmonary function, and reducing exacerbations have positively influenced children and adolescents with CF.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pediatrics
Qiyu Li, Siyuan Liu, Xuemei Ma, Jiaping Yu
Summary: This meta-analysis evaluated the effectiveness and safety of small molecule therapy in children diagnosed with cystic fibrosis (CF). The results showed that CFTR modulators can improve respiratory function, lung clearance index, sweat chloride concentration, and other aspects of function in children with CF, with comparable adverse events compared to the placebo group.
FRONTIERS IN PEDIATRICS
(2022)
Article
Pediatrics
Antonella Tosco, Angela Sepe, Alice Castaldo, Andrea Catzola, Chiara Cimbalo, Valentina Angelini, Gianfranco Vallone, Roberto Buzzetti, Valeria Raia, Maria Grazia Caprio
Summary: The study suggests that p-SWE with LSM may be used for CFLD diagnosis in children, and LSM test outperforms APRI, FIB-4, and GPR tests for early detection of liver fibrosis. LSM shows higher sensitivity and specificity in early detection of liver fibrosis.
TRANSLATIONAL PEDIATRICS
(2021)
Review
Biochemistry & Molecular Biology
Anca Daniela Pinzaru, Cristina Maria Mihai, Tatiana Chisnoiu, Alexandru Cosmin Pantazi, Vasile Valeriu Lupu, Mustafa Ali Kassim Kassim, Ancuta Lupu, Elena Grosan, Ahmed Zaki Naji Al Jumaili, Irina Ion, Gabriela Stoleriu, Ileana Ion
Summary: Cystic fibrosis (CF) is the most common inherited condition that leads to death, especially in those of Caucasian heritage. Around 20% of young adults diagnosed with CF will develop hyperglycemia as a complication, which is later classified as a disease associated with CF. Impaired insulin secretion and glucose intolerance are the primary mechanisms associated with diabetes (type 1 or type 2) and CF. Oxidative stress plays a crucial role in triggering other chronic diseases, including CF-related diabetes. Understanding the connection between CF-related diabetes and oxidative stress is essential for individualized therapies.
Article
Immunology
Shivanthan Shanthikumar, Sarath C. Ranganathan, Richard Saffery, Melanie R. Neeland
Summary: By using high parameter flow cytometry and inflammatory cytokine profiling, the study investigated the immune response in preschool children with CF and healthy controls, revealing pulmonary infiltration of CD66b(+) granulocytes and elevated levels of inflammatory cytokines in CF children. Moreover, the proportions of systemic neutrophils in CF children were positively correlated with age, while CD4 T cells and B cells showed an inverse association with age. This work emphasizes the importance of multiplex immune profiling and advanced analytical pipelines in understanding lung disease mechanisms in childhood.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jonathan R. Dillman, Nadeen Abu Ata, Alexander J. Towbin, Christopher G. Anton, Ethan A. Smith, Bin Zhang, Rebecca Imbus, Jean A. Tkach, Lee A. Denson
Summary: This study assessed the interreader agreement on the use of simplified MaRIA scores to evaluate the inflammatory activity of terminal ileal Crohn disease in children and young adults. The results showed substantial agreement among radiologists and changes in scores after medical therapy, supporting the simplified MaRIA score as an objective measure of intestinal inflammation in this population.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2023)
Review
Pediatrics
Andrew T. Trout, Hedieh Khalatbari, Gbenga Shogbesan, Sobia K. Mirza, Susan E. Sharp, Adina Alazraki, Bradley S. Rostad, Marguerite T. Parisi
Summary: There is currently no standardized approach for I-131 therapy for pediatric Graves disease, which hinders systematic study of outcomes.
PEDIATRIC RADIOLOGY
(2023)
Article
Critical Care Medicine
Matthew K. Wynia, Laurel E. Beaty, Tellen D. Bennett, Nichole E. Carlson, Christopher B. Davis, Bethany M. Kwan, David A. Mayer, Toan C. Ong, Seth Russell, Jeffrey D. Steele, Heather R. Stocker, Adane F. Wogu, Richard D. Zane, Ronald J. Sokol, Adit A. Ginde
Summary: This observational cohort study found that treatment with neutralizing monoclonal antibodies (mAbs) was associated with reduced hospitalization and deaths among COVID-19 outpatients. The benefits of mAb treatment persisted during the Delta variant phase.
Article
Oncology
Gerald G. Behr, Ajaykumar C. Morani, Maddy Artunduaga, Sarah M. Desoky, Monica Epelman, Jonathan Friedman, Shailee Lala, Jayne Seekins, Alexander J. Towbin, Susan J. Back
Summary: This paper provides consensus recommendations for imaging of pediatric patients with a known or suspected primary testicular malignancy at diagnosis and during follow-up. It emphasizes the use of ultrasound as the main imaging modality, with additional cross-sectional imaging modalities being adjusted based on clinical and imaging nuances.
PEDIATRIC BLOOD & CANCER
(2023)
Article
Oncology
Gerald G. Behr, Ajaykumar C. Morani, Maddy Artunduaga, Sarah M. Desoky, Monica Epelman, Jonathan Friedman, Shailee Lala, Jayne Seekins, Alexander J. Towbin, Susan J. Back
Summary: Ovarian tumors in children are rare, with germ cell tumors being the most common subtype. Unlike adults, diagnosing ovarian tumors in children requires a different approach to imaging.
PEDIATRIC BLOOD & CANCER
(2023)
Article
Oncology
Mitchell A. Rees, Cara E. Morin, Gerald G. Behr, J. Christopher Davis, Hollie Lai, Ajaykumar C. Morani, Marguerite T. Parisi, Gaurav Saigal, Sudha Singh, Sireesha Yedururi, Alexander J. Towbin, Barry L. Shulkin
Summary: This paper provides consensus recommendations for imaging of pediatric patients with adrenal malignancies other than neuroblastoma.
PEDIATRIC BLOOD & CANCER
(2023)
Article
Oncology
Gary R. Schooler, Juan C. Infante, Michael Acord, Adina Alazraki, Govind B. Chavhan, James Christopher Davis, Geetika Khanna, Ajaykumar C. Morani, Cara E. Morin, HaiThuy N. Nguyen, Mitchell A. Rees, Raja Shaikh, Abhay Srinivasan, Judy H. Squires, Elizabeth Tang, Paul G. Thacker, Alexander J. Towbin
Summary: This paper provides consensus-based imaging recommendations for the evaluation and follow-up of pediatric patients with primary hepatic malignancies during and after therapy.
PEDIATRIC BLOOD & CANCER
(2023)
Article
Oncology
Joyce Mhlanga, Adina Alazraki, Steve Cho, Hollie Lai, Helen Nadel, Neeta Pandit-Taskar, Jing Qi, Dhanashree Rajderkar, Stephan Voss, Pankaj Watal, Kathleen McCarten
Summary: This paper provides consensus-based imaging recommendations for evaluation and response assessment of patients with Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) at diagnosis and throughout the therapy.
PEDIATRIC BLOOD & CANCER
(2023)
Editorial Material
Oncology
E. R. Tang, A. L. Alazraki, P. G. Thacker, M. B. McCarville, A. J. Towbin
Summary: Pediatric cancer imaging requires experienced radiologists due to its rarity. The Children's Oncology Group Diagnostic Imaging Committee and the Society for Pediatric Radiology Oncology Committee, composed of experts in pediatric cancer imaging, have recently created a series of 23 White Papers as evidence-based imaging recommendations and protocols. This manuscript describes the methods employed in authoring the White Paper series.
PEDIATRIC BLOOD & CANCER
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Cara E. Morin, Amy B. Kolbe, Adina Alazraki, Govind B. Chavhan, Annie Gill, Juan Infante, Geetika Khanna, HaiThuy N. Nguyen, Allison F. O'Neill, Mitchell A. Rees, Akshay Sharma, James E. Squires, Judy H. Squires, Ali B. Syed, Elizabeth R. Tang, Alexander J. Towbin, Gary R. Schooler
Summary: Treatment-induced liver injury is common in children undergoing cancer therapy and can occur during and after treatment. It can result in various acute and long-term effects, including liver failure. Quantitative imaging techniques can be useful for diagnosing and monitoring liver injury. Treatment-related liver lesions and infections can be mistaken for cancer recurrence or liver metastases, but imaging features can help differentiate them. Radiologic evaluation is essential for diagnosing and monitoring hepatic complications of cancer therapy in pediatric patients.
Article
Gastroenterology & Hepatology
Colin T. Shearn, Aimee L. Anderson, Colin G. Miller, Reed C. Noyd, Michael W. Devereaux, Nata Balasubramaniyan, David J. Orlicky, Edward E. Schmidt, Ronald J. Sokol
Summary: This study investigates the impact of thioredoxin reductase 1 (TrxR1) on liver inflammation and injury during cholestatic liver injury. The results show that TrxR1 expression is increased in inflammatory cells and hepatocytes surrounding fibrosis in cholestatic liver injury patients and mouse models. Inhibition of TrxR1 can alleviate inflammation, necrosis, and the expression of pro-inflammatory cytokines, and increase the expression of antioxidant proteins and bile acid transporters. Therefore, the TrxR1 signaling pathway plays an important role in regulating inflammation and bile acid homeostasis in cholestatic liver injury.
HEPATOLOGY COMMUNICATIONS
(2023)
Article
Pediatrics
Alexander J. Towbin, Wen Ye, Suiyuan Huang, Boaz W. Karmazyn, Jean P. Molleston, Prakash Masand, Daniel H. Leung, Samuel Chang, Michael R. Narkewicz, Adina L. Alazraki, A. Jay Freeman, Randolph K. Otto, Nicole Green, Ihab R. Kamel, Wikrom W. Karnsakul, John C. Magee, Jean Tkach, Joseph J. Palermo
Summary: This study aimed to determine the feasibility of quantitative MRI in children with cystic fibrosis (CF) and compare the quantitative MRI-derived metrics with research ultrasound (US). It was found that MRI can provide an objective measure of liver disease in CF patients and support the US determination of advanced liver disease and steatosis.
PEDIATRIC RADIOLOGY
(2023)
Article
Pediatrics
Paul G. Thacker, Adina L. Alazraki, M. Beth McCarville, Elizabeth R. R. Tang, Alexander J. Towbin
PEDIATRIC RADIOLOGY
(2023)
Letter
Pediatrics
Marla B. K. Sammer, Shannon G. Farmakis, Andrew C. Sher, Benjamin H. Taragin, Alexander J. Towbin
PEDIATRIC RADIOLOGY
(2023)
Article
Pediatrics
Tarun Aurora, Audrey Cole, Parul Rai, Paul Lavoie, Carrie Mcivor, Lisa M. Klesges, Guolian Kang, Janaka S. S. Liyanage, Heather M. Brandt, Jane S. Hankins
Summary: This study evaluated the effectiveness of a vaccine strategy bundle in increasing HPV vaccine initiation and completion rates in a specialty clinic setting. By implementing the bundle, which included staff education, provider incentives, offering vaccines in clinics, and verifying vaccine completion, the clinic successfully improved HPV vaccine initiation and completion rates among sickle cell disease patients.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nienke M. Halbmeijer, Wes Onland, Jeroen Dudink, Filip Cools, Anne Debeer, Anton H. van Kaam, Manon J. N. L. Benders, Niek E. van der Aa
Summary: In ventilated infants born preterm, high dose systemic hydrocortisone initiated between 7 and 14 days after birth did not have a significant impact on brain development.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Katherine Melton, Jianfang Liu, Hossein Sadeghi, Maureen George, Arlene Smaldone
Summary: This study aims to identify predictors of change in lung function and body weight during health care transition in cystic fibrosis (CF) patients. The study findings highlight the importance of CF RISE program engagement and reducing gaps in care for improving the transition of adolescents and young adults with CF.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Laura A. Duckworth, Kimberly A. Sutton, Nurmohammad Shaikh, Jinli Wang, Carla Hall-Moore, Lori R. Holtz, Phillip I. Tarr, Ronald C. Rubenstein
Summary: The study tested the usefulness of various biomarkers as indicators of gut dysfunction in cystic fibrosis (CF) and investigated the repeatability of these measures in individuals over short periods and their correlation with clinical outcomes. The results showed that elevated levels of fLcn2 in individuals with CF may predict worsened pulmonary function.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Lindsey Haack, Nikkan Das, Arvind Hoskoppal, Mark Debrunner, Tarek Alsaied, Gaurav Arora
Summary: RAE on ECG has a low positive predictive value for RAE on echocardiogram in previously healthy young patients. The highest yield for RAE on echocardiogram was observed in patients who were <1 year of age, had RAE in the anterior precordial leads, or displayed right ventricular hypertrophy on ECG.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael A. Padula, Khatija Naing, Tara L. Wenger, Irfan Ahmad, Carl H. Coghill, K. Taylor Wild, S. Alex Rottgers, Cory M. Resnick, Jeffrey Goldstein, Zarmina Ehsan, Donna Watkins, Nicole Deptula, Kuan-Chi Lai, Janet Lioy, Semsa Gogcu, Christopher M. Cielo
Summary: This study describes the spectrum of disease and burden of care in infants with congenital micrognathia. The results show that these infants commonly require surgical intervention and tube feedings, and disparities based on race and among centers were identified.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Michael P. Fundora, Manvitha Kalicheti, Guantao Zhao, Kevin O. Maher, Nicoleta Serban
Summary: This study investigated the variation of outpatient opioid prescribing in postoperative pediatric cardiac patients across the US. The results showed that there were significant differences in opioid prescribing by race, ethnicity, sex, and region.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Jia Guo, Brooklyn J. Fraser, Leigh Blizzard, Michael D. Schmidt, Terence Dwyer, Alison J. Venn, Costan G. Magnussen
Summary: There is a correlation between childhood and adulthood cardiorespiratory fitness.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Nianzhou Xiao, Michelle Starr, Adrienne Stolfi, Gilad Hamdani, Shireen Hashmat, Stefan G. Kiessling, Christina Sethna, Mahmoud Kallash, Robyn Matloff, Robert Woroniecki, Keia Sanderson, Ikuyo Yamaguchi, Stephen D. Cha, Michael G. Semanik, Rahul Chanchlani, Joseph T. Flynn, Mark Mitsnefes
Summary: This multicenter study reports that most infants diagnosed with idiopathic hypertension in the NICU will discontinue antihypertensive treatment within 2 years of discharge. Antenatal steroid treatment is associated with a decreased likelihood of needing antihypertensive therapy for more than 1 year.
JOURNAL OF PEDIATRICS
(2024)
Editorial Material
Pediatrics
Kanwaljit Singh, John Concato, Jonathan M. Davis
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Yaxing Meng, Harri Niinikoski, Suvi P. Rovio, Brooklyn J. Fraser, Feitong Wu, Antti Jula, Tapani Ronnemaa, Jorma S. A. Viikari, Olli T. Raitakari, Katja Pahkala, Costan G. Magnussen
Summary: This 26-year study shows a correlation between early-life non-HDL-C levels and future levels. Early dietary counseling can reduce the risk of high pediatric non-HDL-C, emphasizing the importance of early interventions in preventing cardiovascular risks.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kelsey A. B. Gastineau, Rebecca Bell, Allison Hanes, Sandra Mckay, Eric Sigel, Filoteia Popescu, Evan C. Sommer, Shari Barkin
Summary: This study aimed to assess the self-reported counseling outcomes for a firearm safe storage counseling training program provided by the American Academy of Pediatrics. The results demonstrated significant improvement in counseling self-efficacy and frequency one month after the training.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Kathryn E. K. Berlin, William Scott, Sara Dawson, David Brousseau, Joanne M. Lagatta
Summary: This prospective cohort study aimed to investigate the impact of bronchopulmonary dysplasia (BPD) on the health-related quality of life (HRQL) of infants from NICU hospitalization to one year post-discharge. The study found that lower HRQL during NICU stay was associated with earlier gestational age, postnatal corticosteroid usage, outborn status, and gastrostomy tube placement. Lower HRQL at 3 and 12 months post-discharge was associated with readmissions, home oxygen use, parent-reported difficulty breathing, lower developmental scores, and not playing with other children. Most parents reported similar or improved HRQL after discharge, but parents of infants with respiratory symptoms experienced less improvement. Efforts to improve parent HRQL should focus on respiratory symptoms and social isolation.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
Garett J. Griffith, Alan P. Wang, Robert I. Liem, Michael R. Carr, Tyler Corson, Kendra Ward
Summary: This study developed reference values for cardiorespiratory fitness in children aged 6-18 years without underlying heart disease, measured by peak oxygen uptake and treadmill time. Fitness levels increased with age in males but not females. Males generally exhibited higher fitness levels compared to females in the same age groups.
JOURNAL OF PEDIATRICS
(2024)
Article
Pediatrics
David S. Liu, Patricia Miller, Anna Rothenberg, Carley Vuillermin, Peter M. Waters, Andrea S. Bauer
Summary: This study aims to determine if children with elbow flexion contracture (EFC) caused by brachial plexus birth injury (BPBI) are more likely to develop shoulder contracture and undergo surgical treatment. A retrospective review was conducted on children under 2 years old with BPBI who presented to a single children's hospital. The results showed that patients with EFC had reduced shoulder range of motion and higher odds of shoulder contracture and surgical treatment. Prompt referral to a BPBI specialty clinic is recommended for evaluation and potential surgery.
JOURNAL OF PEDIATRICS
(2024)