Article
Medicine, General & Internal
Alexander Hann, Sascha Gruss, Sebastian Goetze, Niklas Mehlhase, Stephan Frisch, Benjamin Walter, Steffen Walter
Summary: This study found a negative correlation between movements and paralinguistic sounds during endoscopy and the satisfaction of the examiner measured with the CSSI. Additionally, the EMG of facial muscles can identify such events and potentially predict their occurrence.
FRONTIERS IN MEDICINE
(2021)
Article
Pharmacology & Pharmacy
Junxiang Li, Xiao Wang, Jin Liu, Xia Wang, Xiangkui Li, Yaping Wang, Wen Ouyang, Jun Li, Shanglong Yao, Zhaoqiong Zhu, Qulian Guo, Yonghao Yu, Jinhai Meng, Yunxia Zuo
Summary: This study compared the sedation properties of Ciprofol and propofol in patients undergoing gastroscopy and colonoscopy. The results showed that Ciprofol was non-inferior to propofol in terms of successful sedation, and had a lower occurrence rate of adverse drug reactions.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2022)
Review
Anesthesiology
J. Robert Sneyd, Anthony R. Absalom, Clemens R. M. Barends, Jordan B. Jones
Summary: Hypotension is common during propofol sedation for colonoscopy and can cause harm to patients.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Pharmacology & Pharmacy
Miaomiao Feng, Gaoxiang Shi, Wenjing Cui, Ning Zhang, Qipeng Xie, Weiwei Zhang
Summary: We conducted a randomized controlled trial to investigate the median effective concentration (EC50) of propofol when combined with different doses of esketamine for inducing appropriate depth of anesthesia during gastrointestinal endoscopy in adults. The study found that esketamine significantly and dose-dependently reduced the dose of propofol required for the procedure.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Gastroenterology & Hepatology
Brian M. Fung, Deanna J. Leon, Lauren N. Beck, James H. Tabibian
Summary: Gastrointestinal endoscopy in patients with advanced liver disease poses challenges for procedural sedation, requiring careful consideration of sedative agent selection and individualized planning.
DIGESTIVE DISEASES AND SCIENCES
(2022)
Article
Anesthesiology
Meizhen Li, Weiqi Ke, Shaohui Zhuang
Summary: This study found that intravenous lidocaine can reduce propofol consumption and shorten the time to loss of consciousness in elderly patients undergoing colonoscopy, with no significant effects on other outcomes.
BMC ANESTHESIOLOGY
(2022)
Article
Anesthesiology
Jing Wang, Xinyan Wang, Haiyang Liu, Ruquan Han
Summary: The study aimed to investigate the effect of butorphanol on postoperative visceral pain in patients undergoing gastrointestinal endoscopy. The results showed that the incidence of visceral pain was significantly lower in patients receiving butorphanol compared to the control group at 10 minutes after the procedure. Therefore, the combination of butorphanol and propofol can effectively reduce postoperative visceral pain in gastrointestinal endoscopy patients.
BMC ANESTHESIOLOGY
(2023)
Article
Anesthesiology
Wenshui Yao, Longxin Zhang, Guolin Lu, Jing Wang, Li Zhang, Yuping Wang, Peihan Xiao, Xiaofen Chen, Chanjuan Chen, Min Zhou
Summary: This study demonstrated that intravenous lidocaine can reduce the amount of propofol needed, provide better sedation and postprocedural pain management, as well as decrease recovery time in pediatric patients undergoing colonoscopy.
BMC ANESTHESIOLOGY
(2021)
Article
Multidisciplinary Sciences
Xiwen Zhu, Xuehan Chen, Xuemei Zheng, Hongyao Lyu, Jie Chen, Ai Yan, Qi Liu, Shiqi Li, Yamei Zhang, Ting Wang, Guangyou Duan, He Huang
Summary: This study compared the use of single-use alfentanil and propofol in colonoscopy patients and found that single-use alfentanil can reduce the incidence of postoperative cognitive decline, as well as decrease the risk of hypotension and shorten discharge time.
Article
Gastroenterology & Hepatology
Casper Steenholdt, Jeppe T. Jensen, Jorn Brynskov, Ann Merete Moller, Anne Christine Limschou, Lars Konge, Peter Vilmann
Summary: This study found that patients with inflammatory bowel disease have higher satisfaction when using deep propofol sedation compared to moderate midazolam and fentanyl sedation during colonoscopy. Patients receiving deep sedation were more likely to choose the same sedation for future colonoscopies and accept more frequent colonoscopies. Assistance from another colonoscopist and procedure disruption due to pain occurred more frequently in the moderate sedation group.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Chemistry, Medicinal
Xianwen Liu, Baofeng Ding, Fu Shi, Yang Zhang, Lei Liu, Yongwei Sha, Tonghang Zhao
Summary: This study compared the efficacy and safety of remimazolam tosilate (RT) and etomidate-propofol (EP) in elderly outpatients undergoing colonoscopy. The results suggest that RT may have similar efficacy but a higher safety profile compared to EP.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Medicine, General & Internal
Krisana Nongnuang, Natirat Limprasert, Sithapan Munjupong
Summary: This study aimed to verify the additive effect of intravenous lidocaine to propofol during colonoscopy. The results showed that intravenous lidocaine significantly reduced propofol use, improved patient satisfaction and sedation score, and had no adverse effects.
Article
Medicine, General & Internal
Feng Guo, De-Feng Sun, Yan Feng, Lin Yang, Jing-Lin Li, Zhong-Liang Sun
Summary: This study aimed to evaluate the efficacy and safety of propofol target-controlled infusion (TCI) in combination with butorphanol for sedation during colonoscopy. The findings suggest that the combined use of propofol and butorphanol can reduce the dose of propofol and decrease the occurrence of anesthesia-related adverse events.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Review
Anesthesiology
Kuo-Chuan Hung, Ming Yew, Yao-Tsung Lin, Jen-Yin Chen, Li-Kai Wang, Ying-Jen Chang, Yang-Pei Chang, Kuo-Mao Lan, Chun-Ning Ho, Cheuk-Kwan Sun
Summary: This study analyzed the use of intravenous or topical lidocaine as an anesthesia adjunct in gastrointestinal endoscopic procedures. The results showed that lidocaine administration reduced post-procedural pain, risks of gag events, and involuntary movement. Only intravenous lidocaine decreased the dosage of propofol required, increased endoscopist satisfaction, and shortened recovery time. Overall, lidocaine appears to be safe and beneficial for improving propofol sedation in gastrointestinal endoscopic procedures.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Review
Medicine, General & Internal
Yun Yang, Haiyang Ji, Yunqiong Lu, Jue Hong, Guang Yang, Xiehe Kong, Jie Liu, Xiaopeng Ma
Summary: This study aimed to evaluate the efficacy of acupuncture therapy combined with propofol sedation during gastrointestinal endoscopy. The results showed that acupuncture reduced sedative consumption and wake-up time, and lowered the risk of adverse events. However, more high-quality clinical studies are needed to confirm these findings.
FRONTIERS IN MEDICINE
(2023)