Article
Medicine, General & Internal
Anna Plocek, Beata Gebora-Kowalska, Wojciech Fendler, Ewa Toporowska-Kowalska
Summary: Diagnosis of gastro-oesophageal reflux disease in children with chronic neurological impairment remains a clinical challenge. This study validated reference values for assessing GOR in these children and determined the optimal cut-off level of the pH-impedance parameter for predicting endoscopic outcomes. Endoscopic findings showed that even with a low number of GOR episodes recorded by pH-impedance, children with chronic NI may still have endoscopic lesions.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Agriculture, Dairy & Animal Science
Ioannis Savvas, Kiriaki Pavlidou, Tilemachos Anagnostou, Eugenia Flouraki, George Kazakos, Dimitrios Raptopoulos
Summary: This systematic review investigates the effect of preoperative fasting duration and drugs on gastro-oesophageal reflux (GOR) in dogs and cats during anaesthesia. The study found that many factors seem to affect the development of GOR, but due to the limited number of studies and low level of evidence, no reliable conclusions can be drawn.
Article
Gastroenterology & Hepatology
Kentaro Sugano, Stuart Jon Spechler, Emad M. El-Omar, Kenneth E. L. McColl, Kaiyo Takubo, Takuji Gotoda, Mitsuhiro Fujishiro, Katsunori Iijima, Haruhiro Inoue, Takashi Kawai, Yoshikazu Kinoshita, Hiroto Miwa, Ken-ichi Mukaisho, Kazunari Murakami, Yasuyuki Seto, Hisao Tajiri, Shobna Bhatia, Myung-Gyu Choi, Rebecca C. Fitzgerald, Kwong Ming Fock, Khean-Lee Goh, Khek Yu Ho, Varocha Mahachai, Maria O'Donovan, Robert Odze, Richard Peek, Massimo Rugge, Prateek Sharma, Jose D. Sollano, Michael Vieth, Justin Wu, Ming-Shiang Wu, Duowu Zou, Michio Kaminishi, Peter Malfertheiner
Summary: This study aims to achieve international consensus on the new definitions of Barrett's esophagus, gastro-esophageal junction, and gastro-esophageal junctional zone, which will provide support for future research addressing many issues concerning this important anatomical area and hopefully lead to improved classification and management of diseases related to the gastro-esophageal junction.
Article
Medicine, General & Internal
Dag Holmberg, Giola Santoni, My von Euler-Chelpin, Martti Farkkila, Joonas H. Kauppila, John Maret-Ouda, Eivind Ness-Jensen, Jesper Lagergren
Summary: Patients with non-erosive gastro-oesophageal reflux disease have a similar incidence of oesophageal adenocarcinoma as the general population.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Article
Nutrition & Dietetics
Yang Chen, Xiaohong Sun, Wenjuan Fan, Jiao Yu, Peng Wang, Dong Liu, Mingwei Song, Shi Liu, Xiuli Zuo, Rong Zhang, Yuantao Hou, Shaomei Han, Yanqing Li, Jun Zhang, Xiaoqing Li, Meiyun Ke, Xiucai Fang
Summary: This study compared dietary and lifestyle triggers between non-erosive reflux disease (NERD) and reflux esophagitis (RE) in Chinese patients and provided evidence for practical dietary modifications for GERD.
Article
Gastroenterology & Hepatology
Akinari Sawada, Benjamin Rogers, Pierfrancesco Visaggi, Nicola de Bortoli, C. Prakash Gyawali, Daniel Sifrim
Summary: Hiatus hernia, less non-acid reflux, and lower post-reflux swallow-induced peristaltic wave index are associated with impaired distal esophageal mucosal integrity.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Article
Psychiatry
Fan Yang, Xin-hui Xie, Xi Li, Hui-na Liao, Bing Zou
Summary: This study aimed to assess the correlation between the incidence of non-erosive reflux disease (NERD) and psychological factors, especially somatoform disorders, and investigate the characteristics of gut microbiome in NERD patients. The study found that NERD symptoms overlap with somatoform disorders and have an impact on patients' daily life quality. Additionally, the diversity of gut microbiome in NERD patients is significantly higher than in healthy controls and is associated with the presence of somatoform disorders.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Respiratory System
Jin-soo Park, Leticia Burton, Hans Van der Wall, Gregory Leighton Falk
Summary: The study revealed frequent early scintigraphic reflux in the pharynx and proximal esophagus in severe reflux patients. A high rate of reflux-related pulmonary aspiration was also observed.
Review
Gastroenterology & Hepatology
Leonardo H. Eusebi, Andrea Telese, Giovanna G. Cirota, Rehan Haidry, Rocco M. Zagari, Franco Bazzoli, Alexander C. Ford
Summary: Gastro-oesophageal reflux is the main risk factor for Barrett's oesophagus, with alcohol consumption and hiatal hernia showing the strongest association with its development. Other potential risk factors such as smoking and obesity did not show significant correlation.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Surgery
Kazuto Tsuboi, Fumiaki Yano, Nobuo Omura, Masato Hoshino, Se-Ryung Yamamoto, Shunsuke Akimoto, Takahiro Masuda, Yuki Sakashita, Toru Ikegami
Summary: This study found that the key factors affecting the efficacy of LF treatment in patients with e-GERD are acid reflux time, longest reflux time, number of refluxes longer than 5 minutes, and distal contractile integral. These factors influence the effectiveness of LF treatment.
Article
Nutrition & Dietetics
Yuanlin Sun, Xueyuan Cao, Donghui Cao, Yingnan Cui, Kaisheng Su, Zhifang Jia, Yanhua Wu, Jing Jiang
Summary: This study systematically elucidated the modifiable factors causally associated with the risk of GORD from multifaceted perspectives, which provided implications for prevention and treatment of GORD.
FRONTIERS IN NUTRITION
(2022)
Article
Gastroenterology & Hepatology
Renske A. B. Oude Nijhuis, Rami Sweis, Humayra Abdul-Razakq, Jeroen M. Schuitenmaker, Terry Wong, Radu-Ionut Rusu, Jac. Oors, Andreas J. P. M. Smout, Albert J. Bredenoord
Summary: This study found that not all patients with nighttime reflux symptoms have pathological acid exposure on every night. Nighttime acid exposure variability is greater than upright acid exposure, and the diagnostic accuracy of pH monitoring within 24 hours is low, improving with longer testing duration.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Veterinary Sciences
Emilie Vangrinsven, Olivier Broux, Laurent Massart, Stephanie Claeys, Cecile Clercx, Frederic Billen
Summary: The study found that using pre- and postoperative antacid treatment in brachycephalic dogs undergoing surgery may improve digestive clinical signs and lesions. The obstruction manoeuvre is an interesting technique for detecting gastro-oesophageal junction abnormalities.
JOURNAL OF SMALL ANIMAL PRACTICE
(2021)
Article
Gastroenterology & Hepatology
Elisa Blasi, Ettore Stefanelli, Renato Tambucci, Silvia Salvatore, Paola De Angelis, Paolo Quitadamo, Claudia Pacchiarotti, Giovanni Di Nardo, Fanj Crocco, Enrico Felici, Valentina Giorgio, Nicoletta Staropoli, Simona Sestito, Efstratios Saliakellis, Osvaldo Borrelli, Licia Pensabene
Summary: This study investigated the prevalence of pediatric non-erosive esophageal phenotypes (NEEPs) and their treatment response. The results showed that functional heartburn may be the most common pediatric NEEP. Long-term follow-up revealed a higher rate of symptom resolution with proton pump inhibitor (PPI) therapy in non-erosive reflux disease (NERD) patients, while other groups did not benefit from extended acid-suppressive treatment.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Review
Agriculture, Dairy & Animal Science
Anna Carolina Fernandez Alasia, Olivier Levionnois, Mathieu Raillard
Summary: Regurgitation and gastro-oesophageal reflux (GOR) are common complications in dogs under anaesthesia. Studies on these complications showed inconsistencies in definitions and assessment methods, making meaningful comparisons difficult. Standardization and re-evaluation of methods may be necessary to address these discrepancies.