4.3 Article

In vitro synergistic/additive activity of levofloxacin with meropenem against Stenotrophomonas maltophilia

Journal

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume 67, Issue 3, Pages 297-300

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2010.02.015

Keywords

Levofloxacin; Meropenem; Stenotrophomonas; Synergy

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Synergy testing of levofloxacin and meropenem by Etest and time-kill assay (TKA) was performed against 30 genetically unique clinical Stenotrophomonas maltophilia isolates. Synergy was demonstrated in 18/30 (60%) isolates by Etest and in 13/30 (43%) by TKA; the remaining isolates were indifferent. Methods showed agreement for 25/30 (83%) of isolates. (C) 2010 Published by Elsevier Inc.

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