GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans
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Title
GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans
Authors
Keywords
Endocrine pancreas, FFAR4, GPR120, Insulin secretion, <em class=EmphasisTypeItalic >n</em>-3 fatty acids, <em class=EmphasisTypeItalic >n</em>-6 fatty acids, NEFA, Pertussis toxin
Journal
DIABETOLOGIA
Volume 57, Issue 6, Pages 1182-1191
Publisher
Springer Nature
Online
2014-03-24
DOI
10.1007/s00125-014-3213-0
References
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Note: Only part of the references are listed.- Gustducin couples fatty acid receptors to GLP-1 release in colon
- (2013) Yan Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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- (2013) M. Fredborg et al. JOURNAL OF ANIMAL SCIENCE
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- (2012) Susanne G. Straub et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets
- (2012) Jalal Taneera et al. Cell Metabolism
- Delta cell secretory responses to insulin secretagogues are not mediated indirectly by insulin
- (2012) A. C. Hauge-Evans et al. DIABETOLOGIA
- Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
- (2012) Atsuhiko Ichimura et al. NATURE
- Unsaturated Fatty Acids Revert Diet-Induced Hypothalamic Inflammation in Obesity
- (2012) Dennys E. Cintra et al. PLoS One
- Drug Discovery Opportunities and Challenges at G Protein Coupled Receptors for Long Chain Free Fatty Acids
- (2012) Nicholas D. Holliday et al. Frontiers in Endocrinology
- Isolated mouse islets respond to glucose with an initial peak of glucagon release followed by pulses of insulin and somatostatin in antisynchrony with glucagon
- (2011) Bo Hellman et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells?
- (2011) N M Whalley et al. JOURNAL OF ENDOCRINOLOGY
- Free Fatty Acid Receptors FFAR1 and GPR120 as Novel Therapeutic Targets for Metabolic Disorders
- (2011) Takafumi Hara et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases
- (2011) Saswata Talukdar et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Cell-to-cell communication and cellular environment alter the somatostatin status of delta cells
- (2010) Catriona Kelly et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Agonism with the omega-3 fatty acids α-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor
- (2010) Rebecca N. Burns et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
- (2010) Da Young Oh et al. CELL
- The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets
- (2010) Catriona Kelly et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Taste Preference for Fatty Acids Is Mediated by GPR40 and GPR120
- (2010) C. Cartoni et al. JOURNAL OF NEUROSCIENCE
- G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell
- (2009) Noel G. Morgan et al. BIOCHEMICAL PHARMACOLOGY
- Lipid receptors and islet function: therapeutic implications?
- (2009) M. A. Kebede et al. DIABETES OBESITY & METABOLISM
- Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells
- (2009) M. Braun et al. DIABETOLOGIA
- Novel selective ligands for free fatty acid receptors GPR120 and GPR40
- (2009) Takafumi Hara et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Distribution and regulation of protein expression of the free fatty acid receptor GPR120
- (2009) Satoshi Miyauchi et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis
- (2009) Atsuhiko Ichimura et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Somatostatin Secreted by Islet -Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function
- (2008) A. C. Hauge-Evans et al. DIABETES
- Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
- (2008) J. de Heer et al. DIABETOLOGIA
- Seven Transmembrane-spanning Receptors for Free Fatty Acids as Therapeutic Targets for Diabetes Mellitus: Pharmacological, Phylogenetic, and Drug Discovery Aspects
- (2008) Stefano Costanzi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Function and expression of somatostatin receptors of the endocrine pancreas
- (2008) Mathias Z. Strowski et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic β cells
- (2008) Toshiki Tanaka et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Colocalization of GPR120 with phospholipase-Cβ2 and α-gustducin in the taste bud cells in mice
- (2008) Shigenobu Matsumura et al. NEUROSCIENCE LETTERS
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