The nucleotide exchange factor SIL1 is required for glucose-stimulated insulin secretion from mouse pancreatic beta cells in vivo

Disruption of MEF2C signaling and loss of sarcomeric and mitochondrial integrity in cancer-induced skeletal muscle wasting

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SEL1L Regulates Adhesion, Proliferation and Secretion of Insulin by Affecting Integrin Signaling

(2013) Giuseppe R. Diaferia et al.   PLoS One

Destruction of Tissue, Cells and Organelles in Type 1 Diabetic Rats Presented at Macromolecular Resolution

(2013) Raimond B. G. Ravelli et al.   Scientific Reports

Endoplasmic Reticulum Stress and Type 2 Diabetes

(2012) Sung Hoon Back et al.   Annual Review of Biochemistry

Regulation of Insulin Secretion in Human Pancreatic Islets

(2012) Patrik Rorsman et al.   Annual Review of Physiology

Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung

(2012) Arne Ittner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural analysis of the Sil1–Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor

(2011) Ming Yan et al.   BIOCHEMICAL JOURNAL

Physiologic action of glucagon on liver glucose metabolism

(2011) C. J. Ramnanan et al.   DIABETES OBESITY & METABOLISM

Mitochondrial signals drive insulin secretion in the pancreatic β-cell

(2011) Andreas Wiederkehr et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Dual and opposing roles of the unfolded protein response regulated by IRE1  and XBP1 in proinsulin processing and insulin secretion

(2011) A.-H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stressed out about obesity: IRE1α–XBP1 in metabolic disorders

(2011) Haibo Sha et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Increased β-cell volume in mice fed a high-fat diet: A dynamic study over 12 months

(2011) Jonatan Ahrén et al.   Islets

PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway

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Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

(2010) J. van Eersel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proinsulin and the Genetics of Diabetes Mellitus

(2009) Michael A. Weiss   JOURNAL OF BIOLOGICAL CHEMISTRY

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2009) Yazi D. Ke et al.   PLoS One

Metabolic cycling in control of glucose-stimulated insulin secretion

(2008) Mette V. Jensen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Novel SIL1 mutations and exclusion of functional candidate genes in Marinesco–Sjögren syndrome

(2008) Anna-Kaisa Anttonen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

GRP78, but Not Protein-disulfide Isomerase, Partially Reverses Hyperglycemia-induced Inhibition of Insulin Synthesis and Secretion in Pancreatic β-Cells

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