Inhibition of NADPH oxidase-1 preserves beta cell function

The role of Nox1 and Nox2 in GPVI-dependent platelet activation and thrombus formation

(2014) T.G. Walsh et al.   Redox Biology

Regulation of NOX-1 expression in beta cells: A positive feedback loop involving the Src-kinase signaling pathway

(2013) J.R. Weaver et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

NADPH Oxidase NOX2 Defines a New Antagonistic Role for Reactive Oxygen Species and cAMP/PKA in the Regulation of Insulin Secretion

(2012) N. Li et al.   DIABETES

Expression of NADPH oxidase in human pancreatic islets

(2012) Eduardo Rebelato et al.   LIFE SCIENCES

Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction

(2012) Jessica R. Weaver et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TLR-4 Signalling Accelerates Colon Cancer Cell Adhesion via NF-κB Mediated Transcriptional Up-Regulation of Nox-1

(2012) D. Peter O'Leary et al.   PLoS One

Circulating pro-inflammatory cytokines and adiponectin in young men with type 2 diabetes

(2010) Sheng-Chiang Su et al.   ACTA DIABETOLOGICA

Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic β-cell dysfunction

(2010) Marta Michalska et al.   BIOSCIENCE REPORTS

Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

(2010) S Wind et al.   BRITISH JOURNAL OF PHARMACOLOGY

The endoplasmic reticulum stress response in the pancreatic β-cell

(2010) A. Volchuk et al.   DIABETES OBESITY & METABOLISM

Plasma concentration of visfatin is a new surrogate marker of systemic inflammation in type 2 diabetic patients

(2010) Young Sun Kang et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

(2010) M. Igoillo-Esteve et al.   DIABETOLOGIA

NADPH Oxidase NOX1 Controls Autocrine Growth of Liver Tumor Cells through Up-regulation of the Epidermal Growth Factor Receptor Pathway

(2010) Patricia Sancho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis

(2010) Benoı̂t Laleu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

(2009) P. Newsholme et al.   DIABETOLOGIA

Association of NAD(P)H Oxidase with Glucose-Induced Insulin Secretion by Pancreatic β-Cells

(2009) D. Morgan et al.   ENDOCRINOLOGY

Oxidative stress: the vulnerable β-cell

(2008) Sigurd Lenzen   BIOCHEMICAL SOCIETY TRANSACTIONS

Renal Redox-Sensitive Signaling, but Not Blood Pressure, Is Attenuated by Nox1 Knockout in Angiotensin II–Dependent Chronic Hypertension

(2008) Alvaro Yogi et al.   HYPERTENSION

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(2008) Herbert Tilg et al.   MOLECULAR MEDICINE