Obesity, diabetes and cancer: insight into the relationship from a cohort with growth hormone receptor deficiency

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

(2014) Anila K. Madiraju et al.   NATURE

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

(2014) Kıvanç Birsoy et al.   NATURE

PI3K and cancer: lessons, challenges and opportunities

(2014) David A. Fruman et al.   NATURE REVIEWS DRUG DISCOVERY

Recommended IGF-I Dosage Causes Greater Fat Accumulation and Osseous Maturation Than Lower Dosage and May Compromise Long-term Growth Effects

(2013) Jaime Guevara-Aguirre et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Metformin Use and All-Cause and Prostate Cancer–Specific Mortality Among Men With Diabetes

(2013) David Margel et al.   JOURNAL OF CLINICAL ONCOLOGY

siRNA-targeted inhibition of growth hormone receptor in human colon cancer SW480 cells

(2013) Dong Zhou   WORLD JOURNAL OF GASTROENTEROLOGY

Lifetime congenital isolated GH deficiency does not protect from the development of diabetes

(2013) Taísa A R Vicente et al.   Endocrine Connections

Dietary intakes of carbohydrates in relation to prostate cancer risk: a prospective study in the Malmö Diet and Cancer cohort

(2012) Isabel Drake et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mortality After Incident Cancer in People With and Without Type 2 Diabetes: Impact of metformin on survival

(2012) C. J. Currie et al.   DIABETES CARE

High Dietary Saturated Fat Intake Accentuates Obesity Risk Associated with the Fat Mass and Obesity–Associated Gene in Adults

(2012) Catherine M. Phillips et al.   JOURNAL OF NUTRITION

Fas apoptosis inhibitory molecule is upregulated by IGF-1 signaling and modulates Akt activation and IRF4 expression in multiple myeloma

(2012) J Huo et al.   LEUKEMIA

Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies

(2011) Rachel Steuerman et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Is there a role for carbohydrate restriction in the treatment and prevention of cancer?

(2011) Rainer J Klement et al.   Nutrition & Metabolism

Combination testing (Stage 2) of the Anti-IGF-1 receptor antibody IMC-A12 with rapamycin by the pediatric preclinical testing program

(2011) E. Anders Kolb et al.   PEDIATRIC BLOOD & CANCER

Altered Expression of Insulin Receptor Isoforms in Breast Cancer

(2011) Jiaqi Huang et al.   PLoS One

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

(2011) J. Guevara-Aguirre et al.   Science Translational Medicine

Familial longevity is marked by enhanced insulin sensitivity

(2010) Carolien A. Wijsman et al.   AGING CELL

Obesity and Cancer

(2010) K. Y. Wolin et al.   ONCOLOGIST

Calorie restriction and cancer prevention: metabolic and molecular mechanisms

(2010) Valter D. Longo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cancer phenotype as the outcome of an evolutionary game between normal and malignant cells

(2009) D Dingli et al.   BRITISH JOURNAL OF CANCER

Insulin Receptor Isoforms and Insulin Receptor/Insulin-Like Growth Factor Receptor Hybrids in Physiology and Disease

(2009) Antonino Belfiore et al.   ENDOCRINE REVIEWS

Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice

(2009) Y. Ikeno et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Conformity to traditional Mediterranean diet and cancer incidence: the Greek EPIC cohort

(2008) V Benetou et al.   BRITISH JOURNAL OF CANCER

Functionally significant insulin-like growth factor I receptor mutations in centenarians

(2008) Y. Suh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA