Nuclear factor κB (NF-κB) suppresses food intake and energy expenditure in mice by directly activating the Pomc promoter

Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

(2012) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased Lipolysis and Energy Expenditure in a Mouse Model with Severely Impaired Glucagon Secretion

(2011) Phing-How Lou et al.   PLoS One

Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis

(2010) A. S. Reed et al.   DIABETES

Epigenetic Changes in the Hypothalamic Proopiomelanocortin and Glucocorticoid Receptor Genes in the Ovine Fetus after Periconceptional Undernutrition

(2010) Adam Stevens et al.   ENDOCRINOLOGY

Constitutively active NF- B triggers systemic TNF -dependent inflammation and localized TNF -independent inflammatory disease

(2010) J. Dong et al.   GENES & DEVELOPMENT

NF-κB Activation in Hypothalamic Pro-opiomelanocortin Neurons Is Essential in Illness- and Leptin-induced Anorexia

(2010) Pil-Geum Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress

(2010) Zhao-Hui Wu et al.   MOLECULAR CELL

Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression

(2010) Hsiangling Teo et al.   NATURE CELL BIOLOGY

Hypothalamic mechanisms in cachexia

(2010) Aaron J. Grossberg et al.   PHYSIOLOGY & BEHAVIOR

Reduced Body Weight and Increased Energy Expenditure in Transgenic Mice Over-Expressing Soluble Leptin Receptor

(2010) Phing-How Lou et al.   PLoS One

Obesity and leptin resistance: distinguishing cause from effect

(2010) Martin G. Myers et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

FoxO1 Inhibits Leptin Regulation of Pro-opiomelanocortin Promoter Activity by Blocking STAT3 Interaction with Specificity Protein 1

(2008) Guoqing Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic regulation and the variability of gene expression

(2008) Jung Kyoon Choi et al.   NATURE GENETICS