Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse

IL-15 Serves as a Costimulator in Determining the Activity of Autoreactive CD8 T Cells in an Experimental Mouse Model of Graft-versus-Host-Like Disease

(2014) F. Miyagawa et al.   JOURNAL OF IMMUNOLOGY

Interleukin-21 Receptor-Mediated Signals Control Autoreactive T Cell Infiltration in Pancreatic Islets

(2012) Tom L. Van Belle et al.   IMMUNITY

The role of interferon alpha in initiation of type I diabetes in the NOD mouse

(2011) Qing Li et al.   CLINICAL IMMUNOLOGY

Interleukin-21 Is Critically Required in Autoimmune and Allogeneic Responses to Islet Tissue in Murine Models

(2011) Helen M. McGuire et al.   DIABETES

A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity

(2011) Helen M. McGuire et al.   IMMUNITY

An indirect role for NK cells in a CD4+ T-cell-dependent mouse model of type I diabetes

(2011) Eveline Angstetra et al.   IMMUNOLOGY AND CELL BIOLOGY

Exposure to IL-15 and IL-21 Enables Autoreactive CD8 T Cells To Respond to Weak Antigens and Cause Disease in a Mouse Model of Autoimmune Diabetes

(2011) S. Ramanathan et al.   JOURNAL OF IMMUNOLOGY

Arresting type 1 diabetes after diagnosis: GAD is not enough

(2011) Chantal Mathieu et al.   LANCET

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial

(2011) Diane K Wherrett et al.   LANCET

Natural killer cells are required for accelerated type 1 diabetes driven by interferon-β

(2010) A. Alba et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A defective Il15 allele underlies the deficiency in natural killer cell activity in nonobese diabetic mice

(2010) H. Suwanai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-15 promotes regulatory T cell function and protects against diabetes development in NK-depleted NOD mice

(2009) Jinxing Xia et al.   CLINICAL IMMUNOLOGY

NOD x 129.H2g7 Backcross Delineates 129S1/SvImJ-Derived Genomic Regions Modulating Type 1 Diabetes Development in Mice

(2009) E. H. Leiter et al.   DIABETES

A protocol for islet isolation from mouse pancreas

(2009) Dong-Sheng Li et al.   Nature Protocols

Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes

(2009) S. Yokoyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-21 signaling is critical for the development of type I diabetes in the NOD mouse

(2008) R. Spolski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA