Acute cannabinoid receptor type 1 (CB1R) modulation influences insulin sensitivity by an effect outside the central nervous system in mice

Cyclic AMP signaling stimulates proteasome degradation of thioredoxin interacting protein (TxNIP) in pancreatic β-cells

(2010) Weijuan Shao et al.   CELLULAR SIGNALLING

CB1 Antagonism Exerts Specific Molecular Effects on Visceral and Subcutaneous Fat and Reverses Liver Steatosis in Diet-Induced Obese Mice

(2010) T. Jourdan et al.   DIABETES

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

(2010) Joseph Tam et al.   JOURNAL OF CLINICAL INVESTIGATION

Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice

(2009) Stéphanie Migrenne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Regulation of MAP Kinase-Directed Mitogenic and Protein Kinase B-Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells

(2009) C. Lipina et al.   DIABETES

CB1 antagonists for obesity—what lessons have we learned from rimonabant?

(2009) Vincenzo Di Marzo et al.   Nature Reviews Endocrinology

HU210-Induced Downregulation in Cannabinoid CB1 Receptor Binding Strongly Correlates with Body Weight Loss in the Adult Rat

(2009) Victoria S. Dalton et al.   NEUROCHEMICAL RESEARCH

Prevention of overweight and obesity from a public health perspective

(2009) Javier Aranceta et al.   NUTRITION REVIEWS

Food Intake-independent Effects of CB1 Antagonism on Glucose and Lipid Metabolism

(2009) Daniela Cota et al.   Obesity

CNS Regulation of Glucose Homeostasis

(2009) Carol K. L. Lam et al.   PHYSIOLOGY

Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice

(2008) Jesse LoVerme et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Peripheral, but Not Central, CB1 Antagonism Provides Food Intake-Independent Metabolic Benefits in Diet-Induced Obese Rats

(2008) R. Nogueiras et al.   DIABETES

Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle

(2008) K. Eckardt et al.   DIABETOLOGIA

Increased Energy Expenditure Contributes More to the Body Weight-Reducing Effect of Rimonabant than Reduced Food Intake in Candy-Fed Wistar Rats

(2008) Andreas W. Herling et al.   ENDOCRINOLOGY

Antidiabetic effects of sub-chronic administration of the cannabinoid receptor (CB1) antagonist, AM251, in obese diabetic (ob/ob) mice

(2008) Nigel Irwin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Reversal of visceral adiposity in candy-diet fed female Wistar rats by the CB1 receptor antagonist rimonabant

(2008) A W Herling et al.   INTERNATIONAL JOURNAL OF OBESITY

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

(2008) Douglas Osei-Hyiaman et al.   JOURNAL OF CLINICAL INVESTIGATION

The Cannabinoid CB1 Receptor Antagonist Rimonabant Stimulates 2-Deoxyglucose Uptake in Skeletal Muscle Cells by Regulating the Expression of Phosphatidylinositol-3-kinase

(2008) I. Esposito et al.   MOLECULAR PHARMACOLOGY

Peripheral Endocannabinoid System Activity in Patients Treated With Sibutramine

(2008) Stefan Engeli et al.   Obesity

Comparison of independent and combined chronic metabolic effects of GIP and CB1 receptor blockade in high-fat fed mice

(2008) Nigel Irwin et al.   PEPTIDES