Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles

Evidence of association with type 1 diabetes in the SLC11A1 gene region

(2011) Jennie HM Yang et al.   BMC Medical Genetics

The Neurosecretory Vesicle Protein Phogrin Functions as a Phosphatidylinositol Phosphatase to Regulate Insulin Secretion

(2010) Leslie A. Caromile et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of the secretory vesicle proteins IA-2 and IA-2β disrupts circadian rhythms of cardiovascular and physical activity

(2009) Soo Mi Kim et al.   FASEB JOURNAL

Disturbances in the secretion of neurotransmitters in IA-2/IA-2β null mice: Changes in behavior, learning and lifespan

(2009) T. Nishimura et al.   NEUROSCIENCE

Loss of the Transcriptional Repressor PAG-3/Gfi-1 Results in Enhanced Neurosecretion that is Dependent on the Dense-Core Vesicle Membrane Protein IDA-1/IA-2

(2009) Tao Cai et al.   PLoS Genetics

Differential modulation of L-type calcium channel subunits by oleate

(2008) Yingrao Tian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

CAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic β Cells

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Autophagy fights disease through cellular self-digestion

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