Article
Oncology
Sishir Doddi, Oscar Salichs, Mahika Mushuni, Siddharth Kunte
Summary: This study aims to analyze the age-adjusted mortality rates for gynecological cancer-related deaths in the United States from 1999 to 2020. Trends were compared by different demographic groups to identify significant disparities in these rates between populations within the United States.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Cell Biology
Junjie Huang, Paul S. F. Chan, Veeleah Lok, Xiao Chen, Hanyue Ding, Yinzi Jin, Jinqiu Yuan, Xiang-qian Lao, Zhi-Jie Zheng, Martin C. S. Wong
Summary: Breast cancer incidence is increasing in many countries globally, with significant rises seen in both older and younger females. Some countries also reported a rise in breast cancer mortality rates. Further research is needed to explore the underlying reasons for these epidemiological trends.
Article
Oncology
Tengteng Wang, Maryam S. Farvid, Jae H. Kang, Michelle D. Holmes, Bernard A. Rosner, Rulla M. Tamimi, Walter C. Willett, A. Heather Eliassen
Summary: This study suggests that greater adherence to a diabetes risk reduction diet after diagnosis is associated with improved survival outcomes among a large number of breast cancer survivors, indicating that postdiagnosis dietary modifications consistent with type II diabetes prevention may be crucial for breast cancer survivors.
Review
Pharmacology & Pharmacy
M. M. N. VUKOVIC, D. B. LAUSEVIC, L. M. VUCKOVIC, Z. M. BUKUMIRIC
Summary: This study analyzed breast cancer mortality data in women in Montenegro and found an increasing trend in mortality rates for the disease. The age group most affected was 55-64 years old. It is necessary to implement urgent action plans to reduce this undesirable trend and strengthen screening and prevention measures.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Oncology
C. Chamalidou, H. Fohlin, P. Albertsson, L. -G. Arnesson, Z. Einbeigi, E. Holmberg, A. Nordenskjold, B. Nordenskjold, P. Karlsson, B. Linderholm
Summary: The study found that patients with invasive lobular carcinoma (ILC) had higher survival rates in the first five years after surgery compared to invasive ductal carcinoma (IDC), but in the 10-15 years after surgery, patients with ILC had a higher excess mortality rate ratio than those with IDC. After 20 years post-surgery, the relative survival rates for ILC and IDC were similar.
Article
Oncology
Ruili Hou, Zhiqi Mu, Weiwei Kang, Zhengran Liu, Buqi Na, Wenliang Niu
Summary: Cancer is a major cause of death in China, particularly in Inner Mongolia. This study aims to estimate cancer mortality in Inner Mongolia, its burden, and its trend over a 60-year time span. The findings may provide baseline data for cancer research.
FRONTIERS IN ONCOLOGY
(2023)
Review
Oncology
Rong Wang, Hong-xin Yang, Jie Chen, Jian-jun Huang, Qing Lv
Summary: This meta-analysis suggests that breast surgery (including modified radical mastectomy and breast-conserving surgery) combined with radiotherapy may be the optimal surgical approach in patients with occult breast cancer. Radiotherapy does not prolong the time of distant metastasis and local recurrences.
FRONTIERS IN ONCOLOGY
(2023)
Article
Obstetrics & Gynecology
Chin-Li Lu, Jia-Ling Wu, Hung-Yuan Li, Santi Martini, Chung-Yi Li
Summary: The prevalence of diabetes in pregnancy (DIP) in Taiwan has increased from 2007 to 2014, with a significant rise in pre-pregnancy type 2 diabetes (T2DM). Socioeconomic variables largely accounted for the increased prevalence of pre-pregnancy type 1 diabetes (T1DM) and gestational diabetes mellitus (GDM), but the prevalence of pre-pregnancy T2DM doubled independently of socioeconomic factors.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Psychiatry
Chu-Syuan Cheng, Wen-Yin Chen, Hu-Ming Chang, Chun-Hung Pan, Sheng-Siang Su, Shang-Ying Tsai, Chiao-Chicy Chen, Chian-Jue Kuo
Summary: This study investigated the incidence and mortality of cancer in patients with schizophrenia and found that the mortality-to-incidence ratio (MIR) was significantly higher in patients with schizophrenia, indicating potential healthcare disparities.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Oncology
Rajesh Sharma
Summary: This study examined the burden of breast cancer in 185 countries in 2018 using data from GLOBOCAN 2018. The study found a significant burden in developing and low-resource economies, calling for a comprehensive approach to cancer management and control. The findings highlight the importance of oncologic infrastructure, breast cancer awareness, and risk factor mitigation in reducing the burden of breast cancer globally.
BREAST CANCER RESEARCH AND TREATMENT
(2021)
Article
Medicine, General & Internal
Sarah M. Lima, Rebecca D. Kehm, Mary Beth Terry
Summary: The incidence and mortality rates of breast cancer are increasing globally, with significant rises seen across all age groups and in most regions. Despite declining fertility rates, the upward trend in breast cancer incidence persists.
Article
Oncology
Chaofan Li, Mengjie Liu, Jia Li, Xixi Zhao, Yusheng Wang, Xi Chen, Weiwei Wang, Shiyu Sun, Cong Feng, Yifan Cai, Fei Wu, Chong Du, Yinbin Zhang, Shuqun Zhang, Jingkun Qu
Summary: Metastasis in breast cancer patients may promote the occurrence of second primary cancers (SPCs) and further increase the risk of cancer-related deaths. Therefore, more attention should be paid to the occurrence of SPCs in patients with metastatic breast cancer (MBC).
FRONTIERS IN ONCOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Xiaoli Fu, Jing Wang, Shuai Jiang, Jian Wu, Zihan Mu, Yanyu Tang, Suxian Wang, Hang Fu, He Ma, Yaojun Zhao
Summary: This study examined the mortality trend of ischemic heart disease (IHD) in Chinese residents from 2010 to 2019 and highlighted the need for public health policies and actions, particularly for female residents aged 75 years and older.
Article
Multidisciplinary Sciences
Vincent Vinh-Hung, Hilde Van Parijs, Olena Gorobets, Christel Fontaine, Nam P. Nguyen, Bhumsuk Keam, Dung Minh Nguyen, Mark De Ridder
Summary: In this study, Gini's mean difference (GMD) was used to evaluate the long-term overall survival of women with breast cancer who received neoadjuvant chemotherapy. The results showed that the classification based on the ratio of positive nodes (LNRc) had a higher GMD value, indicating better prognostic value.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Mate Varnai, Zoltan Kiss, Rolland Gyulai, Judit Olah, Peter Hollo, Gabriella Emri, Andras Csejtei, Istvan Kenessey, Angela Benedek, Zoltan Polanyi, Zsofia Nagy-Erdei, Andrea Daniel, Kata Knollmajer, Gyoergy Rokszin, Ibolya Fabian, Zsofia Barcza, Csaba Polgar, Balazs Nagy, Gabriella Liszkay, Zoltan Voko
Summary: The mortality-to-incidence ratio of melanoma in Hungary has decreased in recent years, with male having higher ratios compared to female; the MIR in Hungary is lower than the European Union average for both sexes, indicating a relatively lower level in Europe; this is driven by the high number of new diagnosed melanoma cases.
FRONTIERS IN ONCOLOGY
(2021)
Article
Gastroenterology & Hepatology
Chin-Hsiao Tseng
Summary: The risk of developing inflammatory bowel disease is lower in patients with type 2 diabetes mellitus who have been treated with metformin, compared to those who have never used it.
JOURNAL OF CROHNS & COLITIS
(2021)
Article
Endocrinology & Metabolism
Chin-Hsiao Tseng
Summary: The study found that the use of metformin is associated with a lower risk of osteoporosis and vertebral fractures. Both sexes in the patient population showed a dose-response pattern, with longer duration of metformin therapy consistently linked to reduced risk. The protective effect of metformin decreased with age but remained significant in patients aged 80 and older.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Chin-Hsiao Tseng
Summary: This study investigated the association between metformin use and malignant brain tumors in patients with type 2 diabetes mellitus. The results showed a reduction in risk of malignant brain tumors associated with metformin use, especially after approximately 2-5 years of use.
Review
Biochemistry & Molecular Biology
Chin-Hsiao Tseng
Summary: Studies have shown a higher risk of gastric cancer in patients with diabetes mellitus, with those who have both conditions experiencing more complications and a poorer prognosis. However, glycemic control may improve in diabetes patients with gastric cancer following gastrectomy.
Article
Respiratory System
Chin-Hsiao Tseng
Summary: A retrospective observational study in Taiwan found that the use of pioglitazone is associated with a significantly lower risk of developing COPD in patients with type 2 diabetes mellitus. No interactions between pioglitazone and COPD risk factors such as pneumonia, pulmonary tuberculosis, and tobacco abuse were noted.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2022)
Review
Andrology
Chin-Hsiao Tseng
Summary: Metformin has various effects on men's health, with potential impacts on erectile dysfunction, steroidogenesis, spermatogenesis, prostate specific antigen, prostatitis, benign prostate hyperplasia, and prostate cancer. Studies on metformin's effects on these conditions are ongoing, with conflicting results on its effectiveness.
WORLD JOURNAL OF MENS HEALTH
(2022)
Article
Otorhinolaryngology
Chin-Hsiao Tseng
Summary: This retrospective cohort study investigated the association between metformin exposure and the risk of hearing loss. The results showed that patients with diabetes who used metformin had a lower risk of hearing loss. The risk reduction was more significant with longer duration of use and higher cumulative dose.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Oncology
Chin-Hsiao Tseng
Summary: This study using Taiwan's National Health Insurance database found that type 2 diabetes patients who use metformin have a significantly lower risk of multiple myeloma, especially in patients who adhere to treatment.
Article
Andrology
Chin-Hsiao Tseng
Summary: This study found an association between the use of pioglitazone and a lower risk of prostate cancer. Among patients using pioglitazone, a cumulative duration of therapy greater than 20.23 months or a cumulative dose greater than 15,330 mg was associated with a significantly reduced risk of prostate cancer, primarily in patients aged less than 65 years.
WORLD JOURNAL OF MENS HEALTH
(2023)
Article
Andrology
Chin-Hsiao Tseng
Summary: This study examined the relationship between the use of metformin and the risk of lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH). The results showed that males with type 2 diabetes who used metformin had a significantly lower risk of LUTS/BPH.
WORLD JOURNAL OF MENS HEALTH
(2023)
Article
Chemistry, Medicinal
Chin-Hsiao Tseng
Summary: This study confirms that metformin can reduce the risk of age-related macular degeneration (AMD) in patients with type 2 diabetes.
Article
Chemistry, Medicinal
Chin-Hsiao Tseng
Summary: This study investigated the potential effects of pioglitazone on inflammatory bowel disease (IBD). Using a nationwide database, the researchers found that pioglitazone did not have any significant impact on IBD risk in patients with type 2 diabetes mellitus.
Article
Dermatology
Chin-hsiao Tseng
Summary: Metformin use is associated with a significantly lower risk of immune-mediated skin diseases but a lack of preventive effect on androgen-mediated skin diseases.
Article
Chemistry, Medicinal
Chin-Hsiao Tseng
Summary: This study aimed to investigate the effect of rosiglitazone on the risk of inflammatory bowel disease (IBD). The results showed that rosiglitazone had no significant effect on the risk of IBD, but there might be a potential benefit on ulcerative colitis (UC).
Article
Oncology
Chin-Hsiao Tseng
Summary: This study aims to investigate the association between TZD use and the risk of multiple myeloma. The findings suggest a lower risk of multiple myeloma associated with TZD, especially in patients aged 65 and above. TZD treatment may provide a survival advantage for patients.