Review
Medical Informatics
Asra Mogharbel, Dawn Dowding, John Ainsworth
Summary: This study identified factors influencing physicians' usage of CPOE systems for medication prescribing, grouped into individual, technological, and organizational themes. The findings can be used to guide implementation and support the use of CPOE systems by physicians, regardless of the setting or duration of system use.
JMIR MEDICAL INFORMATICS
(2021)
Review
Health Care Sciences & Services
Inge Dhamanti, Eva Kurniawati, Elida Zairina, Ida Nurhaida, Salsabila Salsabila
Summary: This scoping review assessed the implementation and outcomes of computerized physician order entry (CPOE) in primary care, finding positive effects on physicians, pharmacists, patients, and primary care providers, with patient safety being the primary goal. More research into the structure, framework, and components of CPOE deployment is needed to improve its adoption in healthcare.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2021)
Review
Health Care Sciences & Services
Khalia Ackermann, Jannah Baker, Malcolm Green, Mary Fullick, Hilal Varinli, Johanna Westbrook, Ling Li
Summary: This scoping review aims to systematically describe studies reporting on the use and evaluation of CCDS systems for the early detection of adult inpatients with sepsis. The current literature on the implementation of CCDS systems for sepsis detection in adult inpatients is highly diverse, with substantial variability in study design, criteria, and outcomes measured. Further research on CCDS system usability, cost, and impact on sepsis morbidity is warranted.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Shuo-Chen Chien, Yen-Po Chin, Chang-Ho Yoon, Chun-You Chen, Chun-Kung Hsu, Chia-Hui Chien, Yu-Chuan Li
Summary: This study aimed to develop a tool to retrieve alert dwell times, explore the impact of different alert characteristics, and compare the impact between professional groups. Results showed a negative correlation between alert quantity and dwell time, and strong correlation of dwell times between different professional groups.
APPLIED SCIENCES-BASEL
(2021)
Article
Multidisciplinary Sciences
Shuo-Chen Chien, Yen-Po (Harvey) Chin, Chang Ho Yoon, Md Mohaimenul Islam, Wen-Shan Jian, Chun-Kung Hsu, Chun-You Chen, Po-Han Chien, Yu-Chuan (Jack) Li
Summary: A novel method was developed to collect alert information from a homegrown CPOE system in Taiwan, providing insights into the number and characteristics of triggered alerts in an academic medical center. The study found that 80.2% of the collected alerts were administrative, while 19.8% were clinical alerts, highlighting the importance of understanding alert categories to reduce alert fatigue.
Article
Computer Science, Information Systems
Sidra Ejaz, Shoab Ahmed Khan, Farhan Hussain
Summary: Uniformity in healthcare delivery is a major concern in the healthcare industry, and information technology can play a crucial role in addressing this issue. This paper proposes a knowledge and data-driven framework for a computerized physician order entry (CPOE) system, which integrates patient data with clinical pathways to extract disease quadruples and provide uniform patient care delivery. The effectiveness of this system has been validated by experts.
Article
Pharmacology & Pharmacy
Stefan Wimmer, Irmgard Toni, Sebastian Botzenhardt, Regina Trollmann, Wolfgang Rascher, Antje Neubert
Summary: This study aims to investigate the impact of a computerized physician order entry (CPOE) system on Adverse Drug Events (ADEs) and potentially harmful ADEs (pot ADEs) in a general pediatric ward. The implementation of a CPOE system resulted in a significant reduction in potentially harmful medication errors.
PHARMACOLOGY RESEARCH & PERSPECTIVES
(2023)
Article
Medical Informatics
Viktoria Jungreithmayr, Andreas D. Meid, Walter E. Haefeli, Hanna M. Seidling
Summary: This study investigated the effects of implementing a CPOE system on the quality of prescription documentation in a large tertiary care hospital. The results showed a significant improvement in the quality of prescription documentation after the implementation of the CPOE system, but certain criteria were still difficult to meet, highlighting the importance of a thorough evaluation for possible improvements.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2021)
Article
Pharmacology & Pharmacy
Matthijs L. Becker, Fatih Baypinar, Marieke Pereboom, Soufiane Lilih, Ruud T. M. van der Hoeven, Thijs J. Giezen, Hylke Jan Kingma
Summary: The study evaluated the effects of implementing advanced algorithms in clinical decision support systems, showing that guideline adherence significantly increased after implementation. Acceptance rates of the advice in the alert ranged from 14% to 90%. One algorithm significantly decreased the number of alerts, while another improved the proportion of patients receiving the correct dose within 48 hours.
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
(2021)
Article
Computer Science, Information Systems
Elizabeth McCourt, Nicola Harper, Margie Butnoris, Richard Friend, Katharine Dekker, Justine Ayre, Bonnie Tai, Anita Pelecanos, Danielle Stowasser, Ian Coombes, Timothy Dunn, Peter Donovan
Summary: This study investigated the impact of a hybrid CPOE-paper prescribing system on prescribing errors at a secondary hospital site. The results showed that the implementation of CPOE led to a significant reduction in prescribing errors and a decreased risk of harm to patients.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2022)
Article
Public, Environmental & Occupational Health
Osama Rabie, Daniyal Alghazzawi, Junaid Asghar, Furqan Khan Saddozai, Muhammad Zubair Asghar
Summary: This study presents a deep learning-based decision support system (DSS) using BiLSTM to accurately predict diabetes. Compared to traditional methods, this model shows higher accuracy and performance.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Geriatrics & Gerontology
Abir Abdellatif, Jacques Bouaud, Carmelo Lafuente-Lafuente, Joel Belmin, Brigitte Seroussi
Summary: The research literature on the outcomes of computerized decision support systems (CDSSs) implemented in nursing homes shows potential benefits in improving clinical and process outcomes. However, the majority of the studies reviewed were observational, highlighting the need for high-quality studies to investigate the effects and limitations of CDSSs in nursing homes.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Review
Computer Science, Information Systems
Thomas Stephen Ledger, Kalissa Brooke-Cowden, Enrico Coiera
Summary: This study aimed to identify interventions for optimizing hospital medication alerts, examine the methods used, populations studied, and evaluate the effects of optimization.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2023)
Article
Computer Science, Interdisciplinary Applications
Shu-Qin Xiao, Jun-E Liu, Hong Chang
Summary: This study explores the impact of computerized physician order entry systems on physician-nurse communication. It finds that quality issues, social factors, and environmental factors all contribute to communication problems between physicians and nurses. To optimize communication between physicians and nurses, improvements in the functionality of order entry systems and interprofessional communication training are needed.
CIN-COMPUTERS INFORMATICS NURSING
(2022)
Article
Computer Science, Information Systems
Reiya Yahada, Tomoyuki Ishida
Summary: This study developed a teleimmersion homecoming support system that allows inpatients to communicate with their families remotely. More than 80% of the subjects evaluated the system positively in terms of necessity, functionality, and presence, but improvements are needed in terms of operability.
INTERNET OF THINGS
(2022)
Article
Cardiac & Cardiovascular Systems
Katherine Phillips, Anuradhaa Subramanian, G. Neil Thomas, Nazish Khan, Joht Singh Chandan, Paul Brady, Tom Marshall, Krishnarajah Nirantharakumar, Larissa Fabritz, Nicola Jaime Adderley
Summary: Between 2008 and 2018, there was an increase in the proportion of AF patients prescribed anticoagulants, driven by the use of non-vitamin K antagonist anticoagulants. The prescription rate for rate control drugs remained constant, while there was a decline in GP prescribing rates for rhythm control drugs.
Article
Pharmacology & Pharmacy
Robin E. Ferner, Julie Mason, Hannah K. Vallance, Tanvi Choudhary, John F. Marriott, Jamie J. Coleman, Sarah K. Pontefract
Summary: In response to the COVID-19 pandemic, Health Education England (HEE) and the University of Birmingham provided National Health Service (NHS) staff free access to SCRIPT, a national eLearning programme for safer prescribing and therapeutics. Over the course of a year, 3412 users registered and opened 17198 modules, with the most popular topics being Adherence and Concordance, Fluids, and Diabetic Emergencies. Marks improved from pre-test to post-test by a median of 2 out of 10, and professionals from various healthcare disciplines utilized the standardized education provided by SCRIPT modules.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Shahin Merat, Elham Jafari, Amir Reza Radmard, Masoud Khoshnia, Maryam Sharafkhah, Alireza Nateghi Baygi, Tom Marshall, Abolfazl Shiravi Khuzani, Kar Keung Cheng, Hossein Poustchi, Reza Malekzadeh
Summary: Fixed-dose combination therapy is effective for preventing major cardiovascular events in individuals with and without presumed non-alcoholic steatohepatitis (pNASH). Among participants with fatty liver and elevated liver enzymes, the use of a polypill can reduce liver enzyme levels.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Kelvin Okoth, Francesca Crowe, Tom Marshall, G. Neil Thomas, Krishnarajah Nirantharakumar, Nicola J. Adderley
Summary: This study investigates the trends in incidence and prevalence of cardiovascular disease (CVD) in young adults in the UK. The results show an overall downward trend in incidence and prevalence for ischaemic heart disease (IHD) and angina, but an upward trend for coronary revascularization, stroke/transient ischaemic attack (TIA), and heart failure (HF). The trends for myocardial infarction (MI) were stable in men and increased in women. The study highlights the worsening trends in CVD among young adults and calls for further investigation and public health intervention.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Ji-Eun Park, Peter Kibe, Godwin Yeboah, Oyinlola Oyebode, Bronwyn Harris, Motunrayo M. Ajisola, Frances Griffiths, Navneet Aujla, Paramjit Gill, Richard J. Lilford, Yen-Fu Chen
Summary: This scoping review aimed to identify factors associated with accessing, utilization, and provision of healthcare services in slums. The study found that factors associated with healthcare in slums include recent migration, knowledge and experience of illness, financial constraints, lack of social support, unfavorable physical environment, sociocultural expectations and stigma, and existing problems in the health system. These findings provide a comprehensive approach to improving health services in slums.
Review
Medicine, General & Internal
Adel Elfeky, Yen-Fu Chen, Amy Grove, Amy Hooper, Anna Wilson, Keith Couper, Marion Thompson, Olalekan Uthman, Rachel Court, Sara Tomassini, Joyce Yeung
Summary: This study aims to answer the question about the clinical effectiveness of perioperative oxygen therapy strategies. Systematic reviews and meta-analyses will be used to summarize evidence on different types of oxygen therapy strategies during different types of surgeries, stages of care, and patient sub-groups. The discussion highlights the need for a panoramic overview of peri-operative oxygen practice to inform clinical practice and identify areas where further research is needed.
SYSTEMATIC REVIEWS
(2022)
Article
Medical Informatics
Jolene Atia, Felicity Evison, Suzy Gallier, Sophie Pettler, Mark Garrick, Simon Ball, Will Lester, Suzanne Morton, Jamie Coleman, Tanya Pankhurst
Summary: Electronic clinical decision support has been effective in reducing unnecessary blood product transfusions, but its impact in specialist settings is limited. Customization and adjustment based on specific circumstances are needed.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2022)
Article
Medicine, Research & Experimental
Christopher J. Weir, Imad Adamestam, Rona Sharp, Holly Ennis, Andrew Heed, Robin Williams, Kathrin Cresswell, Omara Dogar, Sarah Pontefract, Jamie Coleman, Richard Lilford, Neil Watson, Ann Slee, Antony Chuter, Jillian Beggs, Sarah Slight, James Mason, Lucy Yardley, Aziz Sheikh
Summary: This study aims to develop a complex ePrescribing-based Anti-Microbial Stewardship intervention (ePAMS+) and conduct a feasibility trial. ePAMS+ includes educational and organisational behavioural elements, plus guideline-based clinical decision support to aid optimal antimicrobial use in hospital inpatients. The study aims to evaluate the feasibility of ePAMS+ through qualitative and quantitative data collection and analysis, and provide data support for future large-scale trial design.
PILOT AND FEASIBILITY STUDIES
(2023)
Article
Health Care Sciences & Services
Tanya Pankhurst, Laurie Lucas, Steve Ryan, Chris Ragdale, Helen Gyves, Louise Denner, Ian Young, Laura Rathbone, Anwar Shah, Deborah McKee, Jamie J. Coleman, Felicity Evison, Jolene Atia, David Rosser, Mark Garrick, Richard Baker, Suzy Gallier, Simon Ball
Summary: This study aims to describe the benefits of implementing electronic observation charting in intensive care units (ICU). The study evaluated error reduction, time-savings, and costs associated with the transition from paper to digital records. Staff opinions were assessed during the COVID-19 pandemic to determine the efficacy of the electronic system.
Article
Health Care Sciences & Services
Kathrin Cresswell, Susan Hinder, Aziz Sheikh, Sarah Pontefract, Neil W. Watson, David Price, Andrew Heed, Jamie Coleman, Holly Ennis, Jillian Beggs, Antony Chuter, Robin Williams
Summary: This study aimed to understand the existing ePrescribing-based antimicrobial stewardship (AMS) practices in an English hospital. The findings showed that the prescribing and review processes of antimicrobials were characterized by competing priorities and uncertainty, with trade-offs between individual patient benefit and population health benefits. The design of ePrescribing-based interventions needs to consider the complexity of multiple actors and organizations involved, and interventions that reduce uncertainty and promote multidisciplinary collaboration are most likely to be effective in improving AMS practices.
JMIR FORMATIVE RESEARCH
(2023)
Article
Medical Informatics
Jennifer Cooper, Krishnarajah Nirantharakumar, Francesca Crowe, Amaya Azcoaga-Lorenzo, Colin Mccowan, Thomas Jackson, Aditya Acharya, Krishna Gokhale, Niluka Gunathilaka, Tom Marshall, Shamil Haroon
Summary: This study analyzed a large primary care database in England to investigate the prevalence and socio-demographic variation of cardiovascular, renal, and metabolic (CRM) conditions and mental health (MH) conditions. The study found variations in prevalence by sex and ethnicity, suggesting potential differences in clinical presentation and practice. It also highlighted the underrepresentation of undiagnosed conditions, particularly in mental health, in primary care data.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2023)
Review
Multidisciplinary Sciences
Alex Gough, Alice Sitch, Erica Ferris, Tom Marshall
Summary: This study aimed to provide a comprehensive systematic review and meta-analysis of within-subject variability in glycated haemoglobin (HbA1c) measurement. The results showed that HbA1c variability is higher in patients with diabetes and is associated with mean population HbA1c level. These findings highlight the importance of better understanding and accurate estimation of factors associated with HbA1c variability.
Article
Medicine, General & Internal
Sida Chen, Tom Marshall, Christopher Jackson, Jennifer Cooper, Francesca Crowe, Krish Nirantharakumar, Catherine L. Saunders, Paul Kirk, Sylvia Richardson, Duncan Edwards, Simon Griffin, Christopher Yau, Jessica K. Barrett
Summary: Multimorbidity, characterized by the coexistence of multiple chronic conditions, is a rising public health concern. This study utilized electronic primary care records from England to examine the associations between sociodemographic characteristics and the rate of disease progression. The findings indicate strong associations between social deprivation, gender, and age with disease diagnosis, which tend to attenuate with an increase in the number of preexisting conditions.
Article
Health Care Sciences & Services
Christel McMullan, Ameeta Retzer, Sarah E. Hughes, Olalekan Lee Aiyegbusi, Camilla Bathurst, Alan Boyd, Jamie Coleman, Elin Haf Davies, Alastair K. Denniston, Helen Dunster, Chris Frost, Rosie Harding, Amanda Hunn, Derek Kyte, Rebecca Malpass, Gary McNamara, Sandra Mitchell, Saloni Mittal, Philip N. Newsome, Gary Price, Anna Rowe, Wilma van Reil, Anita Walker, Roger Wilson, Melanie Calvert
Summary: This study developed an electronic platform for patients to report their symptoms and conducted usability testing with patient partners and research nurses. The results showed that most people with inflammatory conditions found it easy to report their symptoms using an app on their own device, and they liked the simplicity and responsiveness of the platform. Additionally, research nurses had positive feedback on the usability of the clinical dashboard.
JOURNAL OF PATIENT-REPORTED OUTCOMES
(2023)
Article
Medicine, Research & Experimental
Rachel Adams, Rachel Jordan, Peymane Adab, Tim Barrett, Sheriden Bevan, Lucy Cooper, Ingrid DuRand, Pollyanna Hardy, Nicola Heneghan, Kate Jolly, Sue Jowett, Tom Marshall, Margaret O'Hara, Kiran Rai, Hugh Rickards, Ruth Riley, Steven Sadhra, Sarah Tearne, Gareth Walters, Elizabeth Sapey
Summary: This study aims to reduce absenteeism and presenteeism among NHS staff through an employee health screening clinic, evaluating its clinical and cost-effectiveness through a randomized controlled trial. The trial will recruit 480 participants and evaluate a range of outcomes, including recruitment, referrals, and uptake of recommended services.
PILOT AND FEASIBILITY STUDIES
(2022)