The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita

Conditional depletion of mast cells has no impact on the severity of experimental epidermolysis bullosa acquisita

(2015) Anika Kasprick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Severe adult-onset asthma: A distinct phenotype

(2013) Marijke Amelink et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

B Cells, Dendritic Cells, and Macrophages Are Required To Induce an Autoreactive CD4 Helper T Cell Response in Experimental Epidermolysis Bullosa Acquisita

(2013) H. Iwata et al.   JOURNAL OF IMMUNOLOGY

Methylprednisolone Blocks Autoantibody-Induced Tissue Damage in Experimental Models of Bullous Pemphigoid and Epidermolysis Bullosa Acquisita through Inhibition of Neutrophil Activation

(2013) Lars Hellberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Emerging treatments for pemphigoid diseases

(2013) Ralf J. Ludwig et al.   TRENDS IN MOLECULAR MEDICINE

Genome-wide mapping of gene–microbiota interactions in susceptibility to autoimmune skin blistering

(2013) Girish Srinivas et al.   Nature Communications

Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway

(2013) Gang Li et al.   PLoS Genetics

Retinoic-Acid-Receptor-Related Orphan Nuclear Receptor Alpha Is Required for Natural Helper Cell Development and Allergic Inflammation

(2012) Timotheus Y.F. Halim et al.   IMMUNITY

Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen

(2012) Misa Hirose et al.   JOURNAL OF AUTOIMMUNITY

Recombinant IL-6 treatment protects mice from organ specific autoimmune disease by IL-6 classical signalling-dependent IL-1ra induction

(2012) Unni Krishna S.R.L. Samavedam et al.   JOURNAL OF AUTOIMMUNITY

Pemphigoid diseases

(2012) Enno Schmidt et al.   LANCET

Marketed therapeutic antibodies compendium

(2012) Janice M. Reichert   mAbs

Transcription factor RORα is critical for nuocyte development

(2012) See Heng Wong et al.   NATURE IMMUNOLOGY

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

(2011) Abbas Dehghan et al.   CIRCULATION

Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection

(2011) Jessica L. Werner et al.   INFECTION AND IMMUNITY

Black Patients of African Descent and HLA-DRB1*15:03 Frequency Overrepresented in Epidermolysis Bullosa Acquisita

(2011) Coralie Zumelzu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

(2011) Laura A. Solt et al.   NATURE

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

(2011) John C Chambers et al.   NATURE GENETICS

PI3K  Plays a Critical Role in Neutrophil Activation by Immune Complexes

(2011) S. Kulkarni et al.   Science Signaling

Identification of SR3335 (ML-176): A Synthetic RORα Selective Inverse Agonist

(2010) Naresh Kumar et al.   ACS Chemical Biology

In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes*

(2010) Beatrice Haimovich et al.   CRITICAL CARE MEDICINE

FcγRIIA and FcγRIIIB Are Required for Autoantibody-Induced Tissue Damage in Experimental Human Models of Bullous Pemphigoid

(2010) Xinhua Yu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon Cancer

(2010) Ji Min Lee et al.   MOLECULAR CELL

Differential Association of Circadian Genes with Mood Disorders: CRY1 and NPAS2 are Associated with Unipolar Major Depression and CLOCK and VIP with Bipolar Disorder

(2010) Virginia Soria et al.   NEUROPSYCHOPHARMACOLOGY

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle

(2010) S. Raichur et al.   NUCLEIC ACIDS RESEARCH

Pathogenicity of IgG subclass autoantibodies to type VII collagen: Induction of dermal–epidermal separation

(2009) Andreas Recke et al.   JOURNAL OF AUTOIMMUNITY