Article
Endocrinology & Metabolism
Kieren J. Mather, Ashley H. Tjaden, Adam Hoehn, Kristen J. Nadeau, Thomas A. Buchanan, Steven E. Kahn, Silva A. Arslanian, Sonia Caprio, Karen M. Atkinson, Melanie Cree-Green, Kristina M. Utzschneider, Sharon L. Edelstein
Summary: The RISE Consortium successfully standardized the hyperglycemic clamp methodology across multiple study centers by implementing a two-stage clamp protocol and a centralized algorithm. The approach showed high precision and accuracy, with statistically significant but numerically small differences in achieved glucose concentrations observed across study centers.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Endocrinology & Metabolism
Weifeng Huang, Siwan Li, Jingyi Lu, Yun Shen, Yaxin Wang, Yufei Wang, Kaixuan Feng, Xiaoli Huang, Yan Zou, Linjie Hu, Yihan Lu, Jian Zhou, Yingchuan Li
Summary: This study evaluated the accuracy of the isCGM system in critically ill patients and found suboptimal overall accuracy, particularly in the hypoglycemic range. However, clinical accuracy was acceptable. Further research is needed to determine if the adjunctive use of isCGM can improve glucose management and health outcomes in critically ill patients.
Article
Pediatrics
Mohammed Abdul Wasiq, Sushree Smita Behura, Swaranjika Sahoo, Santosh Kumar Panda
Summary: The study aimed to assess the accuracy and reliability of continuous glucose monitoring (CGM) device in detecting hyperglycaemia during the postoperative period in neonates. Hourly glucose recordings by CGM device and six hourly glucometer glucose measurements were collected in ten surgical neonates. The results showed that CGM device had a sensitivity of 100%, specificity of 93.9%, positive predictive value of 88%, and negative predictive value of 100% for detecting hyperglycaemia. Clarke Error Grid Analysis also demonstrated a high degree of accuracy during the hyperglycaemia period. Conclusion: CGM device is a clinically reliable tool for managing hyperglycaemia in neonates during the postoperative period.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Chemistry, Analytical
Kai Sun, Siyang Liu, Jing Liu, Zhaoyang Ding, Yifei Jiang, Jicheng Zhang, Haobin Chen, Jiangbo Yu, Changfeng Wu, Daniel T. Chiu
Summary: The study introduces an external ratiometric calibration method to improve measurement accuracy of Pdot glucose transducers in implanted CGM systems. This method uses the ratio of oxygen concentrations to correct for signal deviations caused by tissue oxygen fluctuations, achieving higher accuracy glucose measurements.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Vanessa Moscardo, Alia Garcia, Jorge Bondia, Julian Diaz, Agustin Ramos-Prol, Paolo Rossetti
Summary: This study investigates the effect of alcohol consumption on the accuracy of a GOx-CGM in patients with T1D, and suggests that alcohol consumption can affect the accuracy of the CGM, potentially due to the ethanol-induced changes in pH.
Article
Agriculture, Dairy & Animal Science
Francesca Del Baldo, Alessia Diana, Claudia Canton, Nikolina Linta, Roberto Chiocchetti, Federico Fracassi
Summary: Skin thickness affects the accuracy of flash glucose monitoring system (FGMS) measurements, with better accuracy observed in dogs with thicker skin (>5 mm) and lower accuracy in dogs with thinner skin (<5 mm).
Review
Endocrinology & Metabolism
Virginia Bellido, Guido Freckman, Antonio Perez, Rodolfo J. Galindo
Summary: In recent years, there has been an increasing utilization of newer factory-calibrated CGM systems in hospitalized patients, improving the convenience and accuracy of glycemic monitoring. During the COVID-19 pandemic, CGM has been widely used in both intensive care unit and non-intensive care unit settings, with positive results. This review provides an updated assessment of the accuracy of newer CGMs in hospitalized patients, discusses standards for CGM accuracy metrics, examines potential interferences that may affect accuracy, and outlines the steps required for regulatory approval and future research in this field.
ENDOCRINE PRACTICE
(2023)
Review
Chemistry, Analytical
Elena Munoz Fabra, Jose-Luis Diez, Jorge Bondia, Alejandro Jose Laguna Sanz
Summary: CGM monitoring during exercise periods is less accurate and can impact CGM-based treatments for diabetes patients. Most papers did not provide accuracy metrics that differentiated between exercise and rest (non-exercise) periods, hindering comparative data analysis.
Article
Multidisciplinary Sciences
Chavis Srichan, Wachirun Srichan, Pobporn Danvirutai, Chanachai Ritsongmuang, Amod Sharma, Sirirat Anutrakulchai
Summary: This study reports a non-invasive and accurate method for continuous blood glucose monitoring using a multiple photonic band near-infrared sensor. The model achieved high accuracy and precision for diabetes classification, as well as real-time blood glucose monitoring with minimal error. The proposed model is computationally cheaper and less complex compared to previous works.
SCIENTIFIC REPORTS
(2022)
Article
Endocrinology & Metabolism
Madhini Sivasubramanian, Parizad Avari, Clare Gilbert, Louise Doodson, Kate Morgan, Nick Oliver, Pratik Shah
Summary: This study evaluates the accuracy of continuous glucose monitoring (CGM) and its impact on quality of life in children with hyperinsulinaemic hypoglycaemia (HH). The results show that CGM is feasible and clinically acceptable in children with HH, particularly in detecting hypoglycaemia, and its use leads to significant improvement in quality of life.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Satish K. Garg, Mark Kipnes, Kristin Castorino, Timothy S. Bailey, Halis Kaan Akturk, John B. Welsh, Mark P. Christiansen, Andrew K. Balo, Sue A. Brown, Jennifer L. Reid, Stayce E. Beck
Summary: The study evaluated the accuracy and safety of a seventh generation Dexcom CGM in adults with diabetes. Results showed single-digit MARD values with sensors placed on the arm or abdomen, indicating high accuracy.
DIABETES TECHNOLOGY & THERAPEUTICS
(2022)
Article
Chemistry, Analytical
Janis R. Schierbauer, Svenja Guenther, Sandra Haupt, Rebecca T. Zimmer, Beate E. M. Zunner, Paul Zimmermann, Nadine B. Wachsmuth, Max L. Eckstein, Felix Aberer, Harald Sourij, Othmar Moser
Summary: Continuous glucose monitoring (CGM) is an important part of diabetes management, but there is limited data on sensor performance during rapid consumption of different liquids. This study found that the Dexcom G6 CGM system accurately detects glucose during liquid solution challenges in normoglycemic individuals, but sensor performance is influenced by different solutions in people without diabetes.
Article
Chemistry, Analytical
Sissel Banner Lundemose, Christian Laugesen, Ajenthen Gayathri Ranjan, Kirsten Norgaard
Summary: This study assessed the accuracy of three latest factory-calibrated CGM systems in both aerobic exercise and daily life scenarios. The results showed that Dexcom G6 and Guardian 4 demonstrated superior accuracy compared to Freestyle Libre 2 in both exercise and daily life situations.
Article
Endocrinology & Metabolism
Shridhara Alva, Ronald Brazg, Kristin Castorino, Mark Kipnes, David R. Liljenquist, Hanqing Liu
Summary: This study evaluated the performance of the FreeStyle Libre (R) 3 continuous glucose monitoring system (FSL3) and compared it to different reference glucose values. The results showed that the FSL3 demonstrated accurate performance during the 14-day sensor wear period.
Article
Physiology
Xiaoyuan Zhang, Fenghua Sun, Waris Wongpipit, Wendy Y. J. Huang, Stephen H. S. Wong
Summary: The study found that the accuracy of FreeStyle Libre flash glucose monitoring (FGM) was clinically acceptable during postprandial rest and different walking conditions in overweight/obese young adults.
FRONTIERS IN PHYSIOLOGY
(2021)