4.5 Article

Severe leucopenia associated with Sitagliptin use

Journal

DIABETES RESEARCH AND CLINICAL PRACTICE
Volume 91, Issue 2, Pages E30-E32

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.diabres.2010.10.004

Keywords

Dipeptidil-peptidase 4 enzyme; Sitagliptin; Type 2 diabetes; Immunological effects

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We report the case of a type 2 diabetes subject who developed severe leucopenia associated with treatment with the dipeptidil-peptidase 4 enzyme inhibitor Sitagliptin and highlights DPP4 inhibitors as a possible cause of unexplained hematolgical abnormalities in patients receiving DPP4-inhibitor treatment. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

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