Article
Environmental Sciences
Ann M. Vuong, Cai Zhang, Aimin Chen
Summary: Neonicotinoids, a new class of insecticides, may have an impact on insulin and glucose homeostasis parameters, with certain chemicals such as imidacloprid and 5-hydroxy-imidacloprid showing negative associations with insulin levels. Sex, body mass index, and age may also modulate these associations.
Article
Psychology, Developmental
Peiyu Chen, Ana Baylin, Joyce Lee, Galit Levi Dunietz, Alejandra Cantoral, Martha Maria Tellez Rojo, Karen E. Peterson, Erica C. Jansen
Summary: The study examined the relationship between sleep duration, timing, and insulin resistance in Mexican adolescents. Shorter sleep duration and later sleep timing were both independently associated with higher insulin resistance, particularly among girls.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Article
Biochemistry & Molecular Biology
Michalina Gruszczynska, Anna Sadowska-Przytocka, Weronika Szybiak, Barbara Wieckowska, Katarzyna Lacka
Summary: Insulin resistance may play a role in the development of acne vulgaris, as indicated by this cohort study and systematic review. The findings suggest that insulin resistance is more common in acne vulgaris patients and should be considered as an independent factor in diagnosis and treatment.
Article
Endocrinology & Metabolism
Yan Li, Yiwen Wang, Hai Liu, Shaodi Zhang, Cuilian Zhang
Summary: This study explored the association between insulin resistance (IR) and ovarian sensitivity to exogenous gonadotropin (Gn) in women with polycystic ovary syndrome (PCOS). It was found that IR was negatively correlated with ovarian sensitivity. This provides new insights for individualized treatment in PCOS patients with IR undergoing assisted reproductive technology (ART).
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Minna F. Schleu, Beatriz Barreto-Duarte, Maria B. Arriaga, Mariana Araujo-Pereira, Ana Marice Ladeia, Bruno B. Andrade, Maria L. Lima
Summary: The study found that lower levels of VITD are strongly associated with increased insulin resistance in obese women. Different expression profiles of laboratory markers were observed according to 25(OH)D levels.
Article
Public, Environmental & Occupational Health
Yong Chen, Haobin Huang, Xiaowei He, Weiwei Duan, Xuming Mo
Summary: The study found a negative association between blood cobalt concentration and HOMA-IR in female adults, with no significant correlation in the overall population. Participants with the lowest cobalt levels showed a 2.74% increase in HOMA-IR compared to those with the highest cobalt levels, suggesting a potential non-linear relationship between blood cobalt and HOMA-IR.
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Mengxing Wang, Lerong Mei, Aoming Jin, Xueli Cai, Jing Jing, Suying Wang, Xia Meng, Shan Li, Tiemin Wei, Yongjun Wang, Yuesong Pan
Summary: The study found that in patients without diabetes, a high triglyceride glucose (TyG) index was associated with increased atherosclerotic burden and plaques in coronary, intra- and extracranial arteries. Compared with the homeostasis model assessment of insulin resistance (HOMA-IR), the TyG index was more strongly associated with intracranial atherosclerosis.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Endocrinology & Metabolism
Semi Zouiouich, Erikka Loftfield, Inge Huybrechts, Vivian Viallon, Panayiotis Louca, Emily Vogtmann, Philippa M. Wells, Claire J. Steves, Karl-Heinz Herzig, Cristina Menni, Marjo-Riitta Jarvelin, Rashmi Sinha, Marc J. Gunter
Summary: The study revealed that higher levels of HOMA-IR, CRP, and HbA(1c) were associated with lower gut microbiome diversity in both the NFBC1966 and TwinsUK cohorts. This association persisted even after adjusting for BMI and other variables.
Article
Endocrinology & Metabolism
Honglin Sun, Xiaona Chang, Nannan Bian, Yu An, Jia Liu, Song Leng, Guang Wang
Summary: Adipose tissue insulin resistance was strongly associated with serum uric acid levels and hyperuricemia regardless of BMI classification. In men with normal BMI, Adipo-IR, rather than HOMA-IR, was closely associated with hyperuricemia. These findings emphasize the critical role of adipose tissue insulin resistance in serum uric acid metabolism and hyperuricemia.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Huijie Huang, Ai Wang, Li Cong, Yingjuan Zeng
Summary: This study investigated the association between osteocalcin and insulin resistance in men with type 2 diabetes. The results showed an inverse correlation between osteocalcin and the TyG index, particularly in younger patients with lower BMI, poorer glycemic control, without hypertension or smoking.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Elizabeth J. Simpson, Buddhike Mendis, Mandy Dunlop, Hagen Schroeter, Catherine Kwik-Uribe, Ian A. Macdonald
Summary: This study investigated the effects of cocoa flavanols (CF) on insulin-mediated glucose uptake in overweight/obese females, and found that consuming high-flavanol cocoa drink did not improve fasting insulin sensitivity or insulin-mediated glucose uptake. Therefore, there is currently no evidence to support the recommendation of cocoa flavanol supplementation for glycemic control.
Article
Endocrinology & Metabolism
Fernanda Alvarado-Flores, Tomoko Kaneko-Tarui, William Beyer, Jacqueline Katz, Tianjiao Chu, Patrick Catalano, Yoel Sadovsky, Marie-France Hivert, Perrie O'Tierney-Ginn
Summary: Maternal insulin resistance during late pregnancy is associated with the expression of placental miRNA-3940-3p, suggesting a potential regulatory role of this miRNA in modulating maternal insulin resistance.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Leili Rahmatnezhad, Lida Moghaddam-Banaem, Tahereh Behroozi-Lak, Afshin Shiva, Javad Rasouli
Summary: This study aimed to assess the prevalence of insulin resistance (IR) in 4 phenotypes of PCOS, and its relationship with demographic, clinical, and paraclinical individual characteristics in a sample of Iranian PCOS patients. The results showed that PCOS phenotypes were significantly related to insulin resistance and HOMA-IR, with the highest levels observed in phenotype B.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Che-Wei Liao, Chih-Fu Wei, Mei-Huei Chen, Wu-Shiun Hsieh, Ching-Chun Lin, Pau-Chung Chen
Summary: Maternal shift work during pregnancy is associated with childhood overweight and insulin resistance.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Rheumatology
Gurkan Tarcin, Hasan Karakas, Sezgin Sahin, Hande Turan, Mehmet Yildiz, Yavuz Ozer, Fatih Haslak, Dilek Bingol Aydin, Amra Adrovic, Kenan Barut, Ozgur Kasapcopur, Oya Ercan
Summary: Children with juvenile systemic lupus erythematosus (jSLE) were found to have higher insulin resistance even after neutralizing the effects of contributing factors. The elevated insulin resistance in jSLE does not seem to be associated with corticosteroid use, disease duration, disease activity, or autoantibody levels.
CLINICAL RHEUMATOLOGY
(2022)