Article
Endocrinology & Metabolism
Xiaoxia Shen, Siyao He, Jinping Wang, Xin Qian, Hui Wang, Bo Zhang, Yanyan Chen, Hui Li, Guangwei Li
Summary: This study aimed to assess whether a higher insulin response increased the long-term risk of mortality in a non-diabetic population. The results showed that a higher post-load insulin response was significantly associated with a long-term increased risk of all-cause and CVD deaths.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Gastroenterology & Hepatology
Peter Konyn, Omar Alshuwaykh, Brittany B. Dennis, George Cholankeril, Aijaz Ahmed, Donghee Kim
Summary: Gallstone disease is an independent risk factor for NAFLD but is not associated with all-cause mortality in individuals with NAFLD. Screening for gallstone disease may help stratify the risk of all-cause mortality related to gallstone disease.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Geriatrics & Gerontology
Zhong-ming Cai, Man-man Zhang, Ren-qian Feng, Xu-dong Zhou, Hao-man Chen, Zhi-peng Liu, Yan-zhi Wu, Qun-li Lin, Sheng-lie Ye, Cheng-wei Liao, Xue-rong Huang, Le-qiu Sun, Bo Yang, Bei-lei Zhu
Summary: The study found a link between stress hyperglycemia and adverse outcomes in stroke patients, including increased risk of all-cause death, infectious complications, and dysfunction.
Article
Medicine, General & Internal
Donghee Kim, Richie Manikat, Anjiya Shaikh, George Cholankeril, Aijaz Ahmed
Summary: Depression in individuals with NAFLD is associated with increased risk of all-cause and cardiovascular mortality in the United States.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Cardiac & Cardiovascular Systems
Mei Qiu, Xu-Bin Wei, Wei Wei
Summary: Lin et al. conducted a network meta-analysis comparing SGLT2is and GLP1RAs in CV outcome trials, finding that SGLT2is were more effective in reducing HHF risk but not as effective in reducing CV death and ACM. Another meta-analysis directly comparing SGLT2is with GLP1RAs showed that SGLT2is were associated with lower risks of HHF, CV death, and ACM, suggesting that SGLT2is may be preferred over GLP1RAs in preventing CV and all-cause death in patients with T2D.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Gastroenterology & Hepatology
Donghee Kim, Peter Konyn, Keeryth K. Sandhu, Brittany B. Dennis, Amanda C. Cheung, Aijaz Ahmed
Summary: This study demonstrated that metabolic dysfunction-associated fatty liver disease (MAFLD) was associated with an increased risk of all-cause mortality in US adults, while non-alcoholic fatty liver disease (NAFLD) showed no association with all-cause mortality after adjusting for metabolic risk factors. Individuals who met the criteria for MAFLD but not NAFLD had a higher risk of all-cause mortality.
JOURNAL OF HEPATOLOGY
(2021)
Article
Endocrinology & Metabolism
Yahang Liu, Huilin Xu, Jun Li, Yating Yang, Jie Zhang, Xiaoqin Liu, Jiong Li, Yongfu Yu, Guoyou Qin
Summary: This study assessed the independent and combined impacts of visit-to-visit fasting blood glucose variability and mean fasting blood glucose level on all-cause mortality in patients with type 2 diabetes. The results showed that the coexistence of high glycaemic variability and high glucose level increased the risk of premature mortality, highlighting the importance of achieving normal and stable glucose levels simultaneously in glucose management.
DIABETES OBESITY & METABOLISM
(2022)
Article
Geriatrics & Gerontology
Naomi Hirota, Shinya Suzuki, Takuto Arita, Naoharu Yagi, Takayuki Otsuka, Takeshi Yamashita
Summary: The capability of predicting death using biological age determined by 12-lead ECG is comparable to chronological age (CA) among total patients, but shows a significant increase in predictive capability among patients aged 60-74 years old.
Article
Public, Environmental & Occupational Health
Hajin Jang, Rockli Kim, Jong-Tae Lee, Dong Hoon Lee, Edward L. Giovannucci, Hannah Oh
Summary: This study found a J-shaped association between body mass index (BMI) and mortality in Korean adults, meaning both underweight and overweight individuals had an increased risk of death. The association remained even after controlling for confounding factors such as fat-free mass. Abdominal obesity, as measured by waist circumference (WC), was also positively associated with mortality.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Yuxiong Chen, Siqin Feng, Zhen'ge Chang, Yakun Zhao, Yanbo Liu, Jia Fu, Yijie Liu, Siqi Tang, Yitao Han, Shuyang Zhang, Zhongjie Fan
Summary: This study examined the association between serum vitamin D levels and mortality in patients with nonalcoholic fatty liver disease (NAFLD), finding that higher levels of 25(OH)D were independently associated with reduced risk of all-cause and cardiovascular deaths.
Article
Ophthalmology
Bobeck S. Modjtahedi, Jun Wu, Tiffany Q. Luong, Nainesh K. Gandhi, Donald S. Fong, Wansu Chen
Summary: The severity of diabetic retinopathy is significantly associated with the future risk of cerebrovascular accident, myocardial infarction, congestive heart failure, and all-cause mortality in patients with type 2 diabetes mellitus. More severe retinopathy appears to carry a heightened risk for each outcome. Retinal information may provide valuable insights into patients' risk of future vascular disease and death.
Article
Nutrition & Dietetics
Heze Fan, Yuzhi Huang, Haoxuan Zhang, Xueying Feng, Zuyi Yuan, Juan Zhou
Summary: Malnutrition is a well-known risk factor for adverse outcomes in patients with cancer, cardiovascular disease, and chronic kidney disease. However, there is limited epidemiological evidence on its relationship with long-term all-cause mortality and cardiovascular death. This study found that objective nutritional scores, such as GNRI and PNI, were independently associated with increased risk of all-cause death and cardiovascular death. Furthermore, the PNI score showed the highest predictive value for all-cause mortality and cardiovascular death in the general population compared to other nutritional scores.
FRONTIERS IN NUTRITION
(2022)
Article
Urology & Nephrology
Wai H. Lim, Jenny H. C. Chen, Kimberley Minas, David W. Johnson, Maleeka Ladhani, Esther Ooi, Neil Boudville, Carmel Hawley, Andrea K. Viecelli, Matthew Roberts, Kate Wyburn, Rachael Walker, Monique Borlace, Helen Pilmore, Christopher E. Davies, Charmaine E. Lok, Armando Teixeira-Pinto, Germaine Wong
Summary: This study investigates the cause-specific mortality rates between male and female dialysis patients in Australia and New Zealand from 1998 to 2018. It found that female patients had a higher risk of all-cause mortality in the first 5 years after dialysis initiation, primarily due to mortality from infections and dialysis withdrawals.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2023)
Article
Gastroenterology & Hepatology
Chun-Han Lo, Peiyun Ni, Yan Yan, Wenjie Ma, Amit D. Joshi, Long H. Nguyen, Raaj S. Mehta, Paul Lochhead, Mingyang Song, Gary C. Curhan, Yin Cao, Andrew T. Chan
Summary: This study suggests that the use of PPIs is not associated with an increased risk of all-cause mortality and mortality due to major causes after accounting for protopathic bias.
Article
Endocrinology & Metabolism
Dae Kyu Kim, Gang Jee Ko, Yun Jin Choi, Kyung Hwan Jeong, Ju Young Moon, Sang Ho Lee, Hyeon Seok Hwang
Summary: Adequate glycemic control is crucial for improving clinical outcomes in hemodialysis patients with diabetes. This study found a linear relationship between HbA1c levels and the risk of all-cause mortality, with an earlier and more rapid increase in the risk of cardiovascular death.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2022)
