Interactions of amylinergic and melanocortinergic systems in the control of food intake and body weight in rodents

Implication of the melanocortin-3 receptor in the regulation of food intake

(2011) Boman G. Irani et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist

(2010) Shuwen He et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

“Weighing in” on synergy: Preclinical research on neurohormonal anti-obesity combinations

(2010) Jonathan D. Roth et al.   BRAIN RESEARCH

Combined amylin–leptin treatment lowers blood pressure and adiposity in lean and obese rats

(2010) R Seth et al.   INTERNATIONAL JOURNAL OF OBESITY

Melanocortin Signalling and the Regulation of Blood Pressure in Human Obesity

(2010) J. R. Greenfield   JOURNAL OF NEUROENDOCRINOLOGY

Enhanced Weight Loss Following Coadministration of Pramlintide With Sibutramine or Phentermine in a Multicenter Trial

(2010) Louis J. Aronne et al.   Obesity

Effect of MTII on food intake and brain c-Fos in melanocortin-3, melanocortin-4, and double MC3 and MC4 receptor knockout mice

(2010) Neil E. Rowland et al.   PEPTIDES

Brainstem mechanisms of amylin-induced anorexia

(2010) Catarina Soares Potes et al.   PHYSIOLOGY & BEHAVIOR

Multi-hormonal weight loss combinations in diet-induced obese rats: Therapeutic potential of cholecystokinin?

(2010) James L. Trevaskis et al.   PHYSIOLOGY & BEHAVIOR

Insights into amylin–leptin synergy

(2010) James L. Trevaskis et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Potent and Selective Agonism of the Melanocortin Receptor 4 With MK-0493 Does Not Induce Weight Loss in Obese Human Subjects: Energy Intake Predicts Lack of Weight Loss Efficacy

(2009) R Krishna et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mechanisms of Amylin/Leptin Synergy in Rodent Models

(2009) Victoria F. Turek et al.   ENDOCRINOLOGY

Interaction of Leptin and Amylin in the Long-term Maintenance of Weight Loss in Diet-induced Obese Rats

(2009) James L. Trevaskis et al.   Obesity

Sustained Weight Loss Following 12-Month Pramlintide Treatment as an Adjunct to Lifestyle Intervention in Obesity

(2008) S. R. Smith et al.   DIABETES CARE

Amylin-Mediated Restoration of Leptin Responsiveness in Diet-Induced Obesity: Magnitude and Mechanisms

(2008) James L. Trevaskis et al.   ENDOCRINOLOGY

Antiobesity effects of the β-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats

(2008) J D Roth et al.   INTERNATIONAL JOURNAL OF OBESITY

Discovery of Orally Bioavailable 1,3,4-Trisubstituted 2-Oxopiperazine-Based Melanocortin-4 Receptor Agonists as Potential Antiobesity Agents

(2008) Xinrong Tian et al.   JOURNAL OF MEDICINAL CHEMISTRY

Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies

(2008) J. D. Roth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA