Article
Psychiatry
Jieting Zhang, Cuimei Yang, Junhui Leng, Jinting Liu, Pingyuan Gong, Gianluca Esposito
Summary: The study found that Chinese incarcerated males have a relatively higher prevalence of childhood adversity and depressive symptoms. The GG genotype of OXTR rs2254298 is more vulnerable to the impact of childhood adversity on depressive symptoms compared to AA/AG carriers.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Psychiatry
Sunny H. Shin, Gabriela Ksinan Jiskrova, Tiffany Kimbrough, Karen Tabb Dina, Elizabeth Overall Lee, Carl E. Ayers
Summary: Exposure to adverse childhood experiences (ACEs) is associated with postpartum depression (PPD) symptoms, especially among low-income women. Screening for ACEs during prenatal checkups may help identify women at risk of depression and facilitate timely prevention and treatment efforts.
PSYCHIATRY RESEARCH
(2021)
Article
Psychiatry
Elaine Lowry, Amy McInerney, Norbert Schmitz, Sonya S. Deschenes
Summary: This study found that adverse childhood experiences (ACEs) may be associated with cognitive decline partly through depressive symptoms. It also confirmed previous research on the relationship between ACEs and systemic inflammation in adulthood.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Caiyi Zhang, Wei Wang, Yifei Pei, Ying Zhang, Chenlu He, Jingjing Wang, Xiuyin Gao, Hao Hou
Summary: The study found that uncertainty stress plays a key mediating role in connecting benevolent childhood experiences with depressive symptoms. Family relationships can buffer the impact of uncertainty stress on depressive symptoms. Therefore, increasing tolerance for uncertainty and improving family relationships are important ways to protect undergraduates from the impact of depressive symptoms.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Clinical Neurology
Dan Zhang
Summary: This study examines the associations between elder abuse and depressive symptoms among older adults in China and the moderating role of adverse childhood experiences (ACEs) on these relationships. The findings show that elder abuse is significantly associated with increased depressive symptoms, and ACEs moderate the link between elder abuse and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Geriatrics & Gerontology
Chao Li, Shiting Xiang
Summary: This study investigated the association and dose-response relationship between adverse childhood experiences (ACEs) and depressive symptoms in late life among Chinese older adults. It found a dose-response association between ACEs and the prevalence of depressive symptoms, and CRP partially mediated this association. Emphasizing interventions targeting individuals with ACE exposure may minimize the burden of late-life depression in China.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2023)
Article
Psychiatry
Eleonora Iob, Jessie R. Baldwin, Robert Plomin, Andrew Steptoe
Summary: This study suggests that the dysregulated function of the hypothalamic-pituitary-adrenal (HPA) axis might play a role in the relationship between adverse childhood experiences (ACEs) and depression, especially in individuals exposed to multiple ACEs. Lower cortisol levels in early adolescence were found to mediate the association between ACEs and elevated depressive symptoms in early adulthood, independent of genetic factors.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Family Studies
Mengtong Chen, Naiqi Tian, Qingsong Chang
Summary: This study aimed to examine the prevalence of adverse childhood experiences (ACEs) and their associations with depression among college students in Xiamen city, China. The findings revealed that over 35% of the participants reported experiencing at least one type of moderate to extreme childhood maltreatment, with those identifying as LGB reporting higher levels of ACE exposure. Higher levels of ACE exposure were associated with increased risks of depression among Chinese emerging adults. However, sexual identity did not significantly moderate the associations between ACEs and depression. These findings underscore the importance of early screening for ACEs, particularly among sexual minorities, and providing tailored interventions based on ecological backgrounds.
CHILD ABUSE & NEGLECT
(2022)
Article
Pediatrics
Joanne L. Andrade, Young-Rock Hong, Alexandra M. Lee, Darci R. Miller, Charlette Williams, Lindsay A. Thompson, Melissa A. Bright, Michelle Cardel
Summary: This study found a significant association between adverse childhood experiences (ACEs) and markers of obesity and cardiometabolic disease in Hispanic adolescents. Female participants with more reported ACEs were more likely to have higher BMI and body fat percentage, while male participants were more likely to have higher BMI, systolic blood pressure, and diastolic blood pressure. Further research is needed to understand the physiological mechanisms underlying these relationships.
JOURNAL OF PEDIATRICS
(2021)
Article
Psychiatry
Youngmi Kim, Haenim Lee, Aely Park
Summary: This study identified four distinct groups of ACEs, including Child Maltreatment, Household Dysfunction, Violence, and Low Adversity. It found that the Child Maltreatment class had a significantly higher risk of depressive symptoms compared to other ACEs groups, with self-esteem mediating the negative association.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Article
Geriatrics & Gerontology
Maureen Wilson-Genderson, Allison R. Heid, Francine Cartwright, Rachel Pruchno
Summary: The study found that adverse childhood experiences were associated with trajectories of depressive symptoms in late life, and individuals with multiple adverse childhood experiences were more likely to report fear and distress during Hurricane Sandy. Adverse childhood experiences were found to alter the response to traumatic events in adulthood.
AGING & MENTAL HEALTH
(2022)
Article
Family Studies
Sophia L. Roth, Krysta Andrews, Alina Protopopescu, Chantelle Lloyd, Charlene O'Connor, Bruno J. Losier, Ruth A. Lanius, Margaret C. McKinnon
Summary: The study found that adverse childhood experiences (ACEs) can predict negative mental health symptoms in adulthood, and this effect is mediated by symptoms of moral injury (MI) and moderated by difficulties with emotion regulation. These findings emphasize the importance of emotion regulation skills in protecting adult mental health.
CHILD ABUSE & NEGLECT
(2022)
Article
Public, Environmental & Occupational Health
Baojuan Ye, Qipeng Wang, Yanzhen Zhang, Qiang Yang
Summary: This study examined the mediating role of poor sleep quality and psychological inflexibility in the relationship between adverse childhood experiences and depressive symptoms among Chinese senior high school students during the COVID-19 pandemic. The findings suggest potential targets for prevention and intervention in adolescent depressive symptoms.
PSYCHOLOGY HEALTH & MEDICINE
(2023)
Article
Family Studies
Grace S. Hubel, Nada M. Goodrum, Beth L. Sundstrom
Summary: The study found that college students exposed to adverse childhood experiences are influenced by regulatory focus and patient activation in terms of their sexual health attitudes and behaviors. Exposure to ACEs was associated with greater prevention regulatory focus and lower patient activation.
CHILDREN AND YOUTH SERVICES REVIEW
(2021)
Article
Cardiac & Cardiovascular Systems
Sonya S. Deschenes, Mika Kivimaki, Norbert Schmitz
Summary: This study explored the potential mediators of the association between adverse childhood experiences (ACEs) and the risk of coronary heart disease (CHD) in adulthood. The findings revealed that depression symptoms, anxiety symptoms, and cardiometabolic dysregulations partially mediated the relationship between ACEs and CHD. Regular screening and treatment of psychological disorders and cardiometabolic dysregulations may help reduce the long-term health burden of ACEs.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Psychology, Clinical
Srividya N. Iyer, Ashok Malla, Aarati Taksal, Anika Maraj, Greeshma Mohan, Padmavati Ramachandran, Howard C. Margolese, Norbert Schmitz, Ridha Joober, Thara Rangaswamy
Summary: This study investigated the engagement of patients and families in early psychosis services in Canada and India, and found that patients and families in India had higher levels of engagement. Family engagement was found to be a predictor of patient disengagement in Canada, and maintaining family contact could benefit patient engagement regardless of cultural context.
PSYCHOLOGICAL MEDICINE
(2022)
Review
Endocrinology & Metabolism
Marzia Mohseni, Nanna Lindekilde, Genevieve Forget, Rachel J. Burns, Frans Pouwer, Norbert Schmitz, Sonya S. Deschenes
Summary: A systematic review found a positive association between high levels of trait anger/hostility and an increased risk of incident type 2 diabetes. However, there is insufficient evidence to confirm the association between anger/hostility and diabetes-related complications. Further longitudinal studies are needed to investigate this relationship.
CURRENT DIABETES REVIEWS
(2023)
Article
Psychiatry
Elaine Lowry, Amy McInerney, Norbert Schmitz, Sonya S. Deschenes
Summary: This study found that adverse childhood experiences (ACEs) may be associated with cognitive decline partly through depressive symptoms. It also confirmed previous research on the relationship between ACEs and systemic inflammation in adulthood.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2022)
Article
Clinical Neurology
Tea Teras, Suvi Rovio, Jaana Pentti, Jenny Head, Mika Kivimaki, Sari Stenholm
Summary: Increasing and decreasing sleep difficulties may be associated with accelerated decline in cognitive function during retirement transition and post-retirement.
Article
Medicine, General & Internal
Severine Sabia, Aline Dugravot, Damien Leger, Celine Ben Hassen, Mika Kivimaki, Archana Singh-Manoux
Summary: Sleep duration is associated with the incidence of chronic diseases and multimorbidity, but not with mortality. Long sleep duration at age 50 is not significantly associated with the risk of chronic disease.
Article
Public, Environmental & Occupational Health
Akankasha Sen, Anne-Sophie Brazeau, Sonya Deschenes, Hugo Ramiro Melgar-Quinonez, Norbert Schmitz
Summary: This study aims to evaluate the association between depression and ultra-processed food (UPF) consumption as risk factors for developing type 2 diabetes (T2D), and found that individuals with high depressive symptoms and high UPF consumption have a higher risk for T2D. Early management and monitoring of these risk factors may be essential for diabetes prevention.
PUBLIC HEALTH NUTRITION
(2023)
Letter
Cardiac & Cardiovascular Systems
Adam G. Tabak, Naveed Sattar, Mika Kivimaki
Meeting Abstract
Endocrinology & Metabolism
B. Byrne, A. McInerney, S. Deschenes
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Endocrinology & Metabolism
Sonya S. S. Deschenes, Amy McInerney, Finiki Nearchou, Brendan Byrne, Arie Nouwen, Norbert Schmitz
Summary: Depression and anxiety may increase the risk of progressing from prediabetes to type 2 diabetes. Individuals with combined prediabetes and elevated depressive symptoms are at the highest risk of developing diabetes.
Letter
Cardiac & Cardiovascular Systems
Pyry N. Sipila, Mika Kivimaki
Article
Psychiatry
Sally Mustafa, Ashok Malla, Greeshma Mohan, Ramachandran Padmavati, Thara Rangaswamy, Ridha Joober, Norbert Schmitz, Howard Margolese, Srividya N. Iyer
Summary: A longitudinal study compared the quality of life of individuals with first-episode psychosis in Chennai, India and Montreal, Canada. The study found that participants in Chennai had higher general life satisfaction and better social relations compared to those in Montreal. The findings highlight the importance of social support and symptom remission in improving quality of life in early intervention for psychosis.
SCHIZOPHRENIA RESEARCH
(2023)
Article
Psychiatry
Salome M. Xavier, Ashok Malla, Greeshma Mohan, Sally Mustafa, Ramachandran Padmavati, Thara Rangaswamy, Ridha Joober, Norbert Schmitz, Howard C. Margolese, Srividya N. Iyer
Summary: This study examines the impact of trust on psychosis treatment and compares two locations, Montreal, Canada and Chennai, India. The results show that patients and families in Chennai have higher levels of trust in healthcare providers, as well as in the healthcare and mental healthcare systems, compared to Montreal. These differences may be attributed to local cultural values and institutional structures and processes.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2023)
Article
Cell Biology
Andrew Sommerlad, Mika Kivimaki, Eric B. Larson, Susanne Roehr, Kokoro Shirai, Archana Singh-Manoux, Gill Livingston
Summary: The increasing number of people with dementia globally highlights the urgent need to reduce its scale and impact. Lifetime social participation may play a crucial role in reducing dementia risk and could have implications for individual behavior and public health policy. However, more research is needed to fully understand the causal relationship.
Article
Health Care Sciences & Services
Martina Raggi, Aline Dugravot, Linda Valeri, Marcos D. Machado-Fragua, Julien Dumurgier, Mika Kivimaki, Severine Sabia, Archana Singh-Manoux
Summary: Smoking in midlife is associated with social inequalities in dementia at older ages, and part of the social inequalities in dementia is mediated by smoking.
LANCET REGIONAL HEALTH-EUROPE
(2022)