4.7 Article

Racial Disparities in the Treatment of Depression in Low-Income Persons With Diabetes

Journal

DIABETES CARE
Volume 33, Issue 5, Pages 1050-1054

Publisher

AMER DIABETES ASSOC
DOI: 10.2337/dc09-1929

Keywords

-

Funding

  1. National Institutes of Health [R01-CA-92447, HL-67715, P01-DK-20593]
  2. Diversity Supplement Award
  3. National Institute of Diabetes and Digestive and Kidney Diseases [P60-DK-020593]

Ask authors/readers for more resources

OBJECTIVE - Individuals with diabetes are at higher risk for depression than the general population. Although depression can be treated with antidepressant medications, patients with diabetes and comorbid depression often go untreated. The goal of this study was to examine racial disparities in the treatment of depression with antidepressant medication in the southeastern U.S. RESEARCH DESIGN AND METHODS - Cross-sectional data were collected at baseline from 69,068 participants (71% African American, 60% female, and 82% with incomes <$25,000) recruited from community health centers and enrolled in the Southern Cohort Community Study (SCCS). The SCCS is a prospective epidemiological cohort study designed to explore causes of health disparities in adults aged 40-79 years. Binary logistic regression was used to identify factors associated with antidepressant use among those with diabetes (n = 14,279). RESULTS - Individuals with diagnosed diabetes (14,279) were classified with no depressive symptoms (54.7%), or with mild (24.2%), moderate (12.8%), or severe depressive symptoms (8.3%). After controlling for sex, age, insurance, income, education, BMI, smoking status, alcohol consumption, and level of depression, African Americans with diabetes were much less likely to report taking antidepressant medication than whites (adjusted odds ratio 0.32 [95% CI 0.29-0.35], P < 0.0001). CONCLUSIONS - Antidepressant use is much less common among African Americans than among whites with diabetes. Reasons for racial disparities in treatment of depressive symptoms are unclear but may include a combination of differential diagnosis and treatment by health professionals as well as cultural differences in seeking help for emotional distress.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Biology

Updated mortality analysis of the Mallinckrodt uranium processing workers, 1942-2012

Ashley P. Golden, Elizabeth D. Ellis, Sarah S. Cohen, Michael T. Mumma, Richard W. Leggett, Phillip W. Wallace, David Girardi, Janice P. Watkins, Roy E. Shore, John D. Boice

Summary: This study conducted dose-response analysis on the causes of death among early uranium processing workers and found a positive correlation between radiation dose and kidney cancer, and a negative correlation with lung cancer. Additionally, dust measurements were associated with lung diseases.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2022)

Article Biology

Validating the use of census data on education as a measure of socioeconomic status in an occupational cohort

Sarah S. Cohen, Michael T. Mumma, Elizabeth D. Ellis, John D. Boice

Summary: In occupational epidemiology studies, adjusting for smoking status or using a reliable surrogate such as socioeconomic status (SES) is crucial. However, sometimes data on smoking patterns or individual-level SES are not available in occupational cohorts. To address this issue, this study demonstrated a method to obtain and geocode residential address histories and linked them to area-level SES measures. The results showed that area-level SES measures can serve as a reliable surrogate when individual-level indicators are not available for statistical adjustment, especially in outcomes affected by lifestyle factors like smoking.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2022)

Article Biology

Sex-specific lung cancer risk among radiation workers in the million-person study and patients TB-Fluoroscopy

John D. Boice, Elizabeth D. Ellis, Ashley P. Golden, Lydia B. Zablotska, Michael T. Mumma, Sarah S. Cohen

Summary: The study found that the risk of radiation-induced lung cancer is nearly three times higher for women than for men. However, no similar gender differences were found among populations exposed to chronic or fractionated radiation. The analysis of various occupational cohorts showed little difference in gender-specific lung cancer risks.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2022)

Article Biology

Mortality among US military participants at eight aboveground nuclear weapons test series

John D. Boice, Sarah S. Cohen, Michael T. Mumma, Heidi Chen, Ashley P. Golden, Harold L. Beck, John E. Till

Summary: This study tracked the survival status of 114,270 nuclear weapons test participants for up to 65 years. The results showed that most atomic veterans were enlisted men who served in the Navy at the PPG and were born before 1930. The study found no statistically significant radiation associations with mortality among the participants.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2022)

Article Biology

Mortality among workers at the Los Alamos National Laboratory, 1943-2017

John D. Boice, Sarah S. Cohen, Michael T. Mumma, Ashley P. Golden, Sara C. Howard, David J. Girardi, Elizabeth Dupree Ellis, Michael B. Bellamy, Lawrence T. Dauer, Caleigh Samuels, Keith F. Eckerman, Richard W. Leggett

Summary: The study analyzed the mortality experience of 26,328 workers first employed at Los Alamos National Laboratory between 1943 and 1980, with majority being hired before 1960. Most workers had a college degree, and a significant percentage were female, white, and Hispanic. The study found little evidence of radiation increasing the risk of lung cancer or leukemia, but esophageal cancer was associated with radiation and plutonium intakes were linked to an increase in bone cancer. Non-radiation related health issues were also observed among Hispanic workers.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2022)

Article Endocrinology & Metabolism

Energy balance in hypothalamic obesity in response to treatment with a once-weekly GLP-1 receptor agonist

Ashley H. Shoemaker, Heidi J. Silver, Maciej Buchowski, James C. Slaughter, Jack A. Yanovski, Clinton Elfers, Christian L. Roth, M. Jennifer Abuzzahab

Summary: Treatment with a GLP1RA can decrease food intake but also lead to a disproportionate decrease in total energy expenditure compared to changes in body composition.

INTERNATIONAL JOURNAL OF OBESITY (2022)

Article Biology

A million persons, a million dreams: a vision for a national center of radiation epidemiology and biology

John D. Boice, Brian Quinn, Isaf Al-Nabulsi, Armin Ansari, Paul K. Blake, Steve R. Blattnig, Emily A. Caffrey, Sarah S. Cohen, Ashley P. Golden, Kathryn D. Held, Derek W. Jokisch, Richard W. Leggett, Michael T. Mumma, Caleigh Samuels, John E. Till, Sergei Y. Tolmachev, R. Craig Yoder, Joey Y. Zhou, Lawrence T. Dauer

Summary: Epidemiological studies of radiation-exposed populations are crucial for establishing human safety standards and shaping public health policies. The Million Person Study (MPS) focuses on examining health effects following chronic radiation exposure and has provided some insights into the potential risks associated with low-level exposure. Future collaborations and the establishment of a National Center for Radiation Epidemiology and Biology are envisioned for a more comprehensive evaluation of radiation effects.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2022)

Article Biology

Mortality among medical radiation workers in the United States, 1965-2016

John D. Boice, Sarah S. Cohen, Michael T. Mumma, Sara C. Howard, R. Craig Yoder, Lawrence T. Dauer

Summary: This study investigated the radiation risks among medical radiation workers and found an increased risk for lung cancer, particularly among male workers. However, there were no statistically significant radiation associations with other specific causes of death such as leukemia and ischemic heart disease.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2023)

Article Biology

Mortality from leukemia, cancer and heart disease among US nuclear power plant workers, 1957-2011

John D. Boice, Sarah S. Cohen, Michael T. Mumma, Derek A. Hagemeyer, Heidi Chen, Ashley P. Golden, R. Craig Yoder, Lawrence T. Dauer

Summary: The Million Person Study of Low-Dose Health Effects aims to examine the radiation risk for chronic exposures received gradually over time among nuclear power plant workers. Prolonged exposure to radiation was found to increase the risk of leukemia other than CLL among NPP workers, but there was little evidence for a radiation association with all solid cancers, lung cancer, or ischemic heart disease. Increased precision is expected as different cohorts within the MPS are combined for analysis.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2022)

Article Clinical Neurology

Leveraging cardiac magnetic resonance imaging to assess skeletal muscle progression in Duchenne muscular dystrophy

Jacob A. Kaslow, Andrew G. Sokolow, Thomas Donnelly, Maciej S. Buchowski, Bruce M. Damon, Larry W. Markham, W. Bryan Burnette, Jonathan H. Soslow

Summary: Duchenne muscular dystrophy (DMD) is a progressive muscle disease that affects heart and lung function. This study aimed to investigate the relationship between cardiac magnetic resonance imaging (CMR) and functional assessments such as quantitative muscle testing (QMT), spirometry, and accelerometry in patients with DMD. The results showed that imaging of the upper extremity muscles had the strongest correlations with accelerometry, QMT, and spirometry.

NEUROMUSCULAR DISORDERS (2022)

Letter Cardiac & Cardiovascular Systems

Physical Activity, Sedentary Time, and Heart Failure Risk in Low-Income Black and White Adults Living in the Southeastern United States

Sarah H. Brown, Meng Xu, Rachel S. Chang, Sarah S. Cohen, Elvis A. Akwo, Debra D. Dixon, Loren Lipworth, Deepak K. Gupta

CIRCULATION-HEART FAILURE (2022)

Article Biology

Mortality among Tennessee Eastman Corporation (TEC) uranium processing workers, 1943-2019

John D. Boice, Sarah S. Cohen, Michael T. Mumma, Ashley P. Golden, Sara C. Howard, David J. Girardi, Elizabeth D. Ellis, Michael B. Bellamy, Lawrence T. Dauer, Keith F. Eckerman, Richard W. Leggett

Summary: This study investigates the health effects of uranium exposure on female workers during World War II. The results suggest that inhalation of uranium dust may increase the risk of lung cancer and other respiratory diseases, but the impact of radiation on lung cancer risk is not significant.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2023)

Article Oncology

Associations of Dietary Intakes of Carotenoids and Vitamin A with Lung Cancer Risk in a Low-Income Population in the Southeastern United States

Yan Sun, Jie Wu, Hyung-Suk Yoon, Maciej S. Buchowski, Hui Cai, Stephen A. Deppen, Mark D. Steinwandel, Wei Zheng, Xiao-Ou Shu, William J. Blot, Qiuyin Cai

Summary: This study examined the associations between dietary intake of carotenoids and vitamin A and lung cancer risk among low-income African Americans and European Americans. The results showed a positive association between dietary vitamin A intake and lung cancer risk among current smokers, as well as racial-specific associations with adenocarcinoma risk among African Americans. This study contributes to understanding the role of nutrient intake and lung cancer risk among underrepresented populations.

CANCERS (2022)

Article Pediatrics

Spirometry correlates with physical activity in patients with Duchenne muscular dystrophy

Jacob A. Kaslow, Andrew G. Sokolow, Thomas Donnelly, Maciej S. Buchowski, Larry W. Markham, William Bryan Burnette, Jonathan. H. Soslow

Summary: Current studies have mainly focused on respiratory decline and loss of ambulation as indicators of skeletal muscle strength loss in Duchenne muscular dystrophy (DMD). However, this study found that measures of lung function, specifically forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1), showed a strong correlation with functional muscle assessments such as accelerometry and quantitative muscle testing (QMT). Maximal expiratory pressure (MEP) and FVC demonstrated the most robust correlations with total QMT.

PEDIATRIC PULMONOLOGY (2023)

Article Biology

Third mortality follow-up of the Mallinckrodt uranium processing workers, 1942-2019

Cato M. Milder, Sara C. Howard, Elizabeth D. Ellis, Ashley P. Golden, Sarah S. Cohen, Michael T. Mumma, Richard W. Leggett, Benjamin French, Lydia B. Zablotska, John D. Boice

Summary: This third follow-up study of Mallinckrodt uranium processors reinforced the findings of previous studies. The workers showed an excess of brain cancers compared to the general US population, although no radiation dose-response relationship was detected. The association between radiation and kidney cancer persisted, but it may be attributed to the low number of cases at higher doses. Silica dust exposure was associated with nonmalignant kidney disease, but there was no evidence of a dose-response relationship.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2023)

No Data Available