Identification and Saturable Nature of Signaling Pathways Induced by Metreleptin in Humans: Comparative Evaluation of In Vivo, Ex Vivo, and In Vitro Administration

Leptin's Role in Lipodystrophic and Nonlipodystrophic Insulin-Resistant and Diabetic Individuals

(2013) Hyun-Seuk Moon et al.   ENDOCRINE REVIEWS

Effects of Lipid-Lowering Drugs on Irisin in Human Subjects In Vivo and in Human Skeletal Muscle Cells Ex Vivo

(2013) Ioanna Gouni-Berthold et al.   PLoS One

Selective capacity of metreleptin administration to reconstitute CD4+T-cell number in females with acquired hypoleptinemia

(2013) Giuseppe Matarese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leptin, a neuroendocrine mediator of immune responses, inflammation, and sickness behaviors

(2012) Elizabeth D. Carlton et al.   HORMONES AND BEHAVIOR

The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy males

(2011) Emil Wolsk et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Angiotensin II Type-1 Receptor-JAK/STAT Pathway Mediates the Induction of Visfatin in Angiotensin II-Induced Cardiomyocyte Hypertrophy

(2011) Liang Chang et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Efficacy of Metreleptin in Obese Patients With Type 2 Diabetes: Cellular and Molecular Pathways Underlying Leptin Tolerance

(2011) H.-S. Moon et al.   DIABETES

Targeting Curcusomes to Inflammatory Dendritic Cells Inhibits NF-κB and Improves Insulin Resistance in Obese Mice

(2011) Suman Kumar Yekollu et al.   DIABETES

Amylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C2C12 muscle and AML12 liver cell lines

(2011) H.-S. Moon et al.   DIABETOLOGIA

Hypoxia reduces the response of human adipocytes towards TNFα resulting in reduced NF-κB signaling and MCP-1 secretion

(2011) S Famulla et al.   INTERNATIONAL JOURNAL OF OBESITY

Leptin Deficiency Causes Insulin Resistance Induced by Uncontrolled Diabetes

(2010) J. P. German et al.   DIABETES

Leptin and Amylin Act in an Additive Manner to Activate Overlapping Signaling Pathways in Peripheral Tissues: In vitro and ex vivo studies in humans

(2010) H.-S. Moon et al.   DIABETES CARE

Leptin in human physiology and therapeutics

(2010) Tina A. Dardeno et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Prolactin Enhances Insulin-like Growth Factor I Receptor Phosphorylation by Decreasing Its Association with the Tyrosine Phosphatase SHP-2 in MCF-7 Breast Cancer Cells

(2010) Kristopher C. Carver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipodystrophy: pathophysiology and advances in treatment

(2010) Christina G. Fiorenza et al.   Nature Reviews Endocrinology

Pharmacokinetics of Subcutaneous Recombinant Methionyl Human Leptin Administration in Healthy Subjects in the Fed and Fasting States

(2008) Jean L Chan et al.   CLINICAL PHARMACOKINETICS