Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice

RBP4 Activates Antigen-Presenting Cells, Leading to Adipose Tissue Inflammation and Systemic Insulin Resistance

(2014) Pedro M. Moraes-Vieira et al.   Cell Metabolism

Transthyretin Induces Insulin-like Growth Factor I Nuclear Translocation Regulating Its Levels in the Hippocampus

(2014) Marta Vieira et al.   MOLECULAR NEUROBIOLOGY

Plasma Retinol-Binding Protein 4 (RBP4) Levels and Risk of Coronary Heart Disease

(2013) Qi Sun et al.   CIRCULATION

Genetic dissection of retinoid esterification and accumulation in the liver and adipose tissue

(2013) Nuttaporn Wongsiriroj et al.   JOURNAL OF LIPID RESEARCH

Diabetes: a 21st century challenge

(2013) Paul Z Zimmet et al.   Lancet Diabetes & Endocrinology

Clinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy

(2012) Elizabeth J. Ackermann et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Fenretinide Ameliorates Insulin Resistance and Fatty Liver in Obese Mice

(2012) In-uk Koh et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Novel function of transthyretin in pancreatic alpha cells

(2012) Yu Su et al.   FEBS LETTERS

Fenretinide Prevents Lipid-induced Insulin Resistance by Blocking Ceramide Biosynthesis

(2012) Benjamin T. Bikman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Expression of Transthyretin in Leptin-Deficientob/obMice is not Causative for Their Major Phenotypic Abnormalities

(2012) C. Rendenbach et al.   JOURNAL OF NEUROENDOCRINOLOGY

Retinol-Binding Protein 4 Induces Inflammation in Human Endothelial Cells by an NADPH Oxidase- and Nuclear Factor Kappa B-Dependent and Retinol-Independent Mechanism

(2012) K. M. Farjo et al.   MOLECULAR AND CELLULAR BIOLOGY

Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism

(2012) J. Norseen et al.   MOLECULAR AND CELLULAR BIOLOGY

Suppression of retinol-binding protein 4 with RNA oligonucleotide prevents high-fat diet-induced metabolic syndrome and non-alcoholic fatty liver disease in mice

(2011) Yi Tan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Retinol-Binding Protein 4 Is Associated With Prediabetes in Adults From the General Population: The Cooperative Health Research in the Region of Augsburg (KORA) F4 Study

(2011) C. Meisinger et al.   DIABETES CARE

Suppression of choroid plexus transthyretin levels by antisense oligonucleotide treatment

(2010) Merrill D. Benson et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Retinol-Binding Protein-4 in Women With Untreated Essential Hypertension

(2009) A. Solini et al.   AMERICAN JOURNAL OF HYPERTENSION

Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis

(2009) Frederic Preitner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats

(2009) D. M. Erion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice

(2008) Nimesh Mody et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effect of Fenretinide and Low-Dose Tamoxifen on Insulin Sensitivity in Premenopausal Women at High Risk for Breast Cancer

(2008) H. Johansson et al.   CANCER RESEARCH

An RBP4 promoter polymorphism increases risk of type 2 diabetes

(2008) M. van Hoek et al.   DIABETOLOGIA