Pregestational Diabetes Induces Fetal Coronary Artery Malformation via Reactive Oxygen Species Signaling

N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes

(2014) Hoda Moazzen et al.   Cardiovascular Diabetology

Early neonatal death and congenital left coronary abnormalities: Ostial atresia, stenosis and anomalous aortic origin

(2013) Daniela Laux et al.   Archives of Cardiovascular Diseases

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries

(2013) Xueying Tian et al.   CELL RESEARCH

Epicardial HIF signaling regulates vascular precursor cell invasion into the myocardium

(2013) Jiayi Tao et al.   DEVELOPMENTAL BIOLOGY

Regulation and therapeutic strategies of 4-hydroxy-2-nonenal metabolism in heart disease

(2013) V. R. Mali et al.   FREE RADICAL RESEARCH

Reactive Oxygen Species in Vascular Formation and Development

(2013) Yijiang Zhou et al.   Oxidative Medicine and Cellular Longevity

The Transcription Factors Tbx18 and Wt1 Control the Epicardial Epithelial-Mesenchymal Transition through Bi-Directional Regulation of Slug in Murine Primary Epicardial Cells

(2013) Makiko Takeichi et al.   PLoS One

Nitric Oxide Synthase-3 Promotes Embryonic Development of Atrioventricular Valves

(2013) Yin Liu et al.   PLoS One

The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress

(2012) Ying Wang et al.   ACTA PHARMACOLOGICA SINICA

Spectrum of congenital anomalies in pregnancies with pregestational diabetes

(2012) Ester Garne et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Endocardial Cells Form the Coronary Arteries by Angiogenesis through Myocardial-Endocardial VEGF Signaling

(2012) Bingruo Wu et al.   CELL

Genetic Cre-loxP Assessment of Epicardial Cell Fate Using Wt1-Driven Cre Alleles

(2012) Bin Zhou et al.   CIRCULATION RESEARCH

Epithelial-mesenchymal transitions: insights from development

(2012) J. Lim et al.   DEVELOPMENT

NOing the heart: Role of nitric oxide synthase-3 in heart development

(2012) Yin Liu et al.   DIFFERENTIATION

The arterial and cardiac epicardium in development, disease and repair

(2012) Adriana C. Gittenberger-de Groot et al.   DIFFERENTIATION

Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction

(2012) Yin Liu et al.   EUROPEAN HEART JOURNAL

Prepregnancy Body Mass Index and Congenital Heart Defects among Offspring: A Population-based Study

(2012) Nicolas L. Madsen et al.   Congenital Heart Disease

HIF-1α dysfunction in diabetes

(2011) Hariharan Thangarajah et al.   CELL CYCLE

Signaling During Epicardium and Coronary Vessel Development

(2011) José María Pérez-Pomares et al.   CIRCULATION RESEARCH

Diabetes-Induced Birth Defects: What Do We Know? What Can We Do?

(2011) E. Albert Reece   Current Diabetes Reports

Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2

(2011) J. A. Guadix et al.   DEVELOPMENT

WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways

(2011) Alexander von Gise et al.   DEVELOPMENTAL BIOLOGY

Congenital Heart Disease in Pregnancies Complicated by Maternal Diabetes Mellitus

(2011) Lukas A. Lisowski et al.   HERZ

Retinoic Acid and VEGF Delay Smooth Muscle Relative to Endothelial Differentiation to Coordinate Inner and Outer Coronary Vessel Wall Morphogenesis

(2010) Ana P. Azambuja et al.   CIRCULATION RESEARCH

Superoxide induced by a high-glucose concentration attenuates production of angiogenic growth factors in hypoxic mouse mesenchymal stem cells

(2010) T. Ishizuka et al.   JOURNAL OF ENDOCRINOLOGY

Coronary arteries form by developmental reprogramming of venous cells

(2010) Kristy Red-Horse et al.   NATURE

Endogenous retinoic acid regulates cardiac progenitor differentiation

(2010) S.-C. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoplastic coronary artery disease causing sudden death. Report of two cases and review of the literature

(2009) Fabio De Giorgio et al.   CARDIOVASCULAR PATHOLOGY

The Role of Hypoxia in Development of the Mammalian Embryo

(2009) Sally L. Dunwoodie   DEVELOPMENTAL CELL

Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin

(2009) Ofelia M Martínez-Estrada et al.   NATURE GENETICS

Diabetes mellitus and birth defects

(2008) Adolfo Correa et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Oxidative stress during diabetic pregnancy disrupts cardiac neural crest migration and causes outflow tract defects

(2008) Sarah C. Morgan et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

(2008) Bin Zhou et al.   NATURE